Immunology Seminar
When
Event Details
November 3rd at 14:00-15:00
Online event
in Zoom
Flyer
Vijay Kuchroo, Director, The Gene Lay Institute of Institute of Immunology and Inflammation
Briahm and Women’s Hospital and Harvard Medical School, Boston
Role of TIM-3 in regulating stem-like T cells and anti-tumor immunity
Host: Riitta Lahesmaa (rilahes@utu.fi)
Link to seminar: https://utu.zoom.us/j/62229630803
Register for the Immunology Seminar Series email list to get calendar invitation to the online seminar: https://link.webropolsurveys.com/S/D29C32AA6E8A2F7A
Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience. For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.
Dr. Vijay Kuchroo is the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School and Senior Scientist at Brigham and Women’s Hospital. Vijay Kuchroo is also an Institute member of the Broad Institute of Harvard and MIT, a senior investigator at Klarman Cell Observatory project and Food Allergy Scientific Initiative (FASI) project. He is the founding Director of the Gene Lay Institute of Immunology and Inflammation at Harvard Medical School, Brigham and Women’s Hospital and Mass General Hospital, Boston.
His major research interests include autoimmune diseases – particularly the role of co-stimulation – the genetic basis of experimental autoimmune encephalomyelitis and multiple sclerosis, and cell surface molecules and regulatory factors that regulate induction of T cell tolerance and dysfunction. His laboratory has made several transgenic mice that serve as animal models for human multiple sclerosis. His laboratory also first described TIM family of genes and identified Tim-3 as an inhibitory receptor expressed on T cells, which is now being exploited for cancer immunotherapy. He was first to describe the development of a highly pathogenic Th17 cells which has been shown to induce multiple different autoimmune diseases in humans. A paper describing development of Th17 authored by Dr. Kuchroo has been one of the highest cited papers in Immunology. More recently, we have begun to study the impact of neuroimmune interactions at the barrier surfaces in the induction and regulation of tissue inflammation.