Event Details

5^th May at 11.00
Onsite event
in Aud. Biochemistry, BioCity 3rd floor

Prof. Karl Munger, Tufts University, Dept. of Biomedical Sciences, Boston, USA
Cracking the HPV Cancer Code: Oncoproteins and Tumor Suppressor Networks

Host: John Eriksson (john.eriksson@bioscience.fi)

Coffee, tea, and sweet buns served from 10:45

We are delighted to welcome Prof. Karl Munger, a leading authority to define our understanding of the molecular basis of HPV-driven cancer. His work has been instrumental in establishing how HPV oncoproteins, particularly E6 and E7, disable key tumor suppressors such as RB and p53, reprogram cell cycle control, and induce genomic instability. More recently, his research has uncovered how HPV targets additional regulatory axes, including PTPN14-mediated differentiation control and major signaling pathways such as Hippo, Wnt, and NOTCH, revealing a far more integrated and systems-level logic of carcinogenesis. By combining molecular virology, cell biology, and advanced genetic and functional models (including in vivo papillomavirus systems), Prof. Munger has helped reshape our understanding of how viral proteins rewire host cellular networks to drive malignant transformation.

The seminar will provide a state-of-the-art overview of HPV carcinogenesis, from foundational mechanisms to emerging concepts defining the next phase of the field. If you would like to meet with Prof. Munger during his visit, please contact John Eriksson (john.eriksson@bioscience.fi).

We look forward to seeing you at the seminar!