FICAN Seminar
FICAN Seminar
May 25th at 15:00
Online event
in Teams
Kaapo Seppälä, Tampere University, Tampere University Hospital
Molecular profiling and patient-derived cancer organoids – towards clinical applications
This time the seminar is organized by FICAN Mid. The seminar will be held online and is open to everyone interested in cancer research.
Click here for more details and to join the meeting
Novel tools to aid decision-making in challenging clinical decisions are required, and precision medicine holds great promise in delivering improvements to progressing cancers. Applications to steer oncological management have been largely based on genomic targeting of the drugs, but only less than third of patients benefit from genomically targeted approach, and the success is highly context-depending. Functional precision oncology models such as patient derived organoid technology enable individualized cell culture and personalized testing for each tumor. Organoids may serve as a clinical tool to guide traditional primary tumor NGS interpretation, and facilitate in vitro response prediction to therapy. Data-intensive models for tumor microenvironment co-culture and combination pharmacotyping are needed.