5^th December at 10:00
Onsite event
in Ministeri auditorium, BioCity 1^st floor

Coffee, with tea and buns served at 9.45

Prof. Dr. Med. Rudolf Leube, RTWH Aachen University, Germany
Intermediate filaments: Fine tuners of epithelial tissue plasticity

Host: Diana Toivola (diana.toivola@abo.fi)

Prof. Leube is very well known for his research work on different cellular and molecular aspects of the biology of intermediate filaments in different tissues and model systems. His work has revealed seminal work for example on the dynamic movements of these cytoskeletal proteins using high-resolution live cell imaging methods.  Do not miss this opportunity to learn from a leading expert in cytoskeletal biology. https://www.moca.rwth-aachen.de

Selected publications

Plasticity of cytoplasmic intermediate filament architecture determines cellular functions. Schwarz N, Leube RE. Curr Opin Cell Biol. 2023 Dec;85:102270. doi: 10.1016/j.ceb.2023.102270.

A keratin code defines the textile nature of epithelial tissue architecture. Di Russo J, Magin TM, Leube RE. Curr Opin Cell Biol. 2023 Dec;85:102236. doi: 10.1016/j.ceb.2023.102236..

Intermediate filament network perturbation in the C. elegans intestine causes systemic dysfunctions. Geisler F, Remmelzwaal S, Jankowski V, Schmidt R, Boxem M, Leube RE. Elife. 2023 Jun 7;12:e82333. doi: 10.7554/eLife.82333.

Synaptoporin and parathyroid hormone 2 as markers of multimodal inputs to the auditory brainstem. Reuss S, Linsmayer D, Balmaceda-Braun J, von Rittberg J, Mitz S, Disque-Kaiser U, Usdin T, Leube RE. J Chem Neuroanat. 2023 Jul;130:102259. doi: 10.1016/j.jchemneu.2023.102259.

Quantitative mapping of keratin networks in 3D. Windoffer R, Schwarz N, Yoon S, Piskova T, Scholkemper M, Stegmaier J, Bönsch A, Di Russo J, Leube RE. Elife. 2022 Feb 18;11:e75894. doi: 10.7554/eLife.75894.

Combining Image Restoration and Traction Force Microscopy to Study Extracellular Matrix-Dependent Keratin Filament Network Plasticity. Yoon S, Windoffer R, Kozyrina AN, Piskova T, Di Russo J, Leube RE. Front Cell Dev Biol. 2022 May 11;10:901038. doi: 10.3389/fcell.2022.901038. eCollection 2022.

Regulation of keratin network dynamics by the mechanical properties of the environment in migrating cells. Pora A, Yoon S, Dreissen G, Hoffmann B, Merkel R, Windoffer R, Leube RE. Sci Rep. 2020 Mar 12;10(1):4574. doi: 10.1038/s41598-020-61242-5.