October 28^th at 15:00
On-site event
Medisiina D, Lauren 2

Tero Aittokallio, InFLAMES visiting professor
Predictive modelling of treatment responses in hematological malignancies

Professor Tero Aittokalllio is currently working as a group leader in Oslo University Hospital, Institute for Cancer Research and University of Oslo, Oslo Centre for Biostatistics and Epidemiology. He is also a Group Leader in Institute for Molecular Medicine Finland (FIMM), University of Helsinki. His group has expertise in integrating multi-omics profiling and clinical information from cancer patients using mathematical and statistical approaches such as machine learning and network modeling. Tero’s research profile can be found here: https://ous-research.no/aittokallio/

Selected publications

Zhao Z, Wang S, Zucknick M, Aittokallio T. Tissue-specific identification of multi-omics features for pan-cancer drug response prediction. iScience 2022;25:104767. doi: 10.1016/j.isci.2022.104767

Ianevski A, Giri AK, Aittokallio T. Fully-automated and ultra-fast cell-type identification using specific marker combinations from single-cell transcriptomic data. Nature Communications 2022; 13: 1246. http://doi.org/10.1038/s41467-022-28803-w.

Cichońska A, Ravikumar B, Allaway RJ, Wan F, Park S, Isayev O, Li S, Mason M, Lamb A, Tanoli Z, Jeon M, Kim S, Popova M, Capuzzi S, Zeng J, Dang K, Koytiger G, Kang J, Wells CI, Willson TM; IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium, Oprea TI, Schlessinger A, Drewry DH, Stolovitzky G, Wennerberg K, Guinney J, Aittokallio T. Crowdsourced mapping of unexplored target space of kinase inhibitors. Nature Communications 2021;12:3307. doi: 10.1038/s41467-021-23165-1.

Akimov Y, Bulanova D, Timonen S, Wennerberg K, Aittokallio T. Improved detection of differentially represented DNA barcodes for high-throughput clonal phenomics. Molecular Systems Biology 2020; 16: e9195. doi.org/10.15252/msb.20199195

Ianevski A, Lahtela J, Javarappa KK, Sergeev P, Ghimire BR, Gautam P, Vähä-Koskela M, Turunen L, Linnavirta N, Kuusanmäki H, Kontro M, Porkka K, Heckman CA, Mattila P, Wennerberg K, Giri AK, Aittokallio T.  Patient-tailored design for selective co-inhibition of leukemic cell subpopulations. Science Advances 2020; 7: eabe4038, DOI: 10.1126 / sciadv.abe4038