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UID:251@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20190708T110000
DTEND;TZID=Europe/Helsinki:20190708T120000
DTSTAMP:20231013T061536Z
URL:https://biocityturku.fi/events/receptor-programme-seminar-by-professor
 -harriet-wikman-kocher-university-medical-center-hamburg-eppendorf-germany
 /
SUMMARY:Receptor Programme seminar by Professor Harriet Wikman-Kocher (Univ
 ersity Medical Center Hamburg-Eppendorf\, Germany)
DESCRIPTION:Title: Liquid biopsy approaches in brain metastasis research\
 nHosts: Harri Härmä (harri.harma@utu.fi) and Jukka Westermarck (jukka.we
 stermarck@bioscience.fi)\n\nBiography: PhD from University of Helsinki in 
 2000. Group leader since 2005 and Professor since 2016 at Department of Tu
 mor Biology\, University Hospital Hamburg-Eppendorf\, Germany. Original ar
 ticles: 69\, review articles: 10.\n\nThe main research interest of Profess
 or Wikman-Kocher´s group is to understand the biology behind the differen
 t steps of the metastatic cascade. They are interested in finding genes an
 d pathways important for these processes and to investigate their function
 s by using both patient material as well as cell-culture based model syste
 ms. In particular\, they are interested in investigating genetic factors l
 eading to early dissemination (i.e. research on circulating and disseminat
 ed tumor cells) of both lung and breast tumors\, and to better understand 
 the site-specific metastasis such as brain metastasis formation in various
  epithelial tumors. Their aim is to use these markers in liquid biopsy spe
 cimens in order to improve cancer diagnostics and also treatment of cancer
  patients.\n\nSelected publications:\n\n 	Riebensahm et al. Clonality of C
 irculating Tumor Cells in Breast Cancer Brain Metastases Patients. Breast 
 Cancer Res. In press\, 2019\n 	Hanssen et al. Frequency of Circulating Tum
 or Cells (CTC) in Patients with Brain Metastases: Implications as a Risk A
 ssessment Marker in Oligo-Metastatic Disease. Cancers 10(12): 527\, 2018\n
  	Berger et al. Identification of a High-Level MET Amplification in CTCs a
 nd cfTNA of an ALK-Positive NSCLC Patient Developing Evasive Resistance to
  Crizotinib. J Thorac Oncol. 13(12): e243-246\, 2018\n 	Hohensee et al. PT
 EN mediates the cross talk between breast and glial cells in brain metasta
 ses leading to rapid disease progression. Oncotarget 8(4):6155-6168\, 2016
 \n 	Werner et al.  Suppression of early hematogenous dissemination of hu
 man breast cancer cells to bone marrow by retinoic Acid-induced 2. Cancer 
 Discov. 5(5):506-519\, 2015\n
CATEGORIES:BiocityTurku events
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