BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN BEGIN:VEVENT UID:858@biocityturku.fi DTSTART;TZID=Europe/Helsinki:20260203T140000 DTEND;TZID=Europe/Helsinki:20260203T150000 DTSTAMP:20260202T100118Z URL:https://biocityturku.fi/events/immunology-seminar-makinen/ SUMMARY:Immunology Seminar: Mäkinen DESCRIPTION:3rd February at 14-15\nVirtual event\nin Zoom\nFlyer\n\n \; \n\nTaija Mäkinen\, University of Helsinki\nLymphatic vasculature as a gu ardian of tissue homeostasis and inflammation\n\nHost: Professor Riitta La hesmaa (rilahes@utu.fi)\n\nLink to join the seminar: https://utu.zoom.us/j /69783530648\n\nRegister for the Immunology Seminar Series email list to g et calendar invitations to the online seminars: https://link.webropolsurve ys.com/S/D29C32AA6E8A2F7A\n\nImmunology seminar series is jointly organise d by the Finnish Society for Immunology\, InFLAMES Flagship and Turku Bios cience. For further information contact Anne Lahdenperä  (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi)\, University of Turku.\n\n \;\n\n Taija Mäkinen obtained her PhD from the University of Helsinki and comple ted postdoctoral training at the Max Planck Institute of Neurobiology in M artinsried\, Germany. She previously served as a group leader at the Cance r Research UK London Research Institute (now the Francis Crick Institute) and later as Professor at Uppsala University. In 2024\, she returned to Fi nland and currently serves as Director of the Wihuri Research Institute an d Professor at the Faculty of Medicine\, University of Helsinki. Her resea rch focuses on the mechanisms regulating the lymphatic vascular system and its roles in health and disease.\n\n \;\n\nSelected publications\n\nK raft M\, Schoofs H\, Petkova M\, Andrade J\, Grosso AR\, Benedito R\, De R oo AK\, Boon LM\, Vikkula M\, Kapp FG\, Hägerling R\, Potente M\, Mäkine n T. Angiopoietin-TIE2 feedforward circuit promotes PIK3CA-driven venous m alformations. Nat Cardiovasc Res. 2025 Jul\;4(7):801-820. doi: 10.1038/s44 161-025-00655-9.\n\nSchoofs H\, Daubel N\, Schnabellehner S\, Grönloh MLB \, Palacios Martínez S\, Halme A\, Marks AM\, Jeansson M\, Barcos S\, Bra kebusch C\, Benedito R\, Engelhardt B\, Vestweber D\, Gaengel K\, Linsenme ier F\, Schürmann S\, Saharinen P\, van Buul JD\, Friedrich O\, Smith RS\ , Majda M\, Mäkinen T. Dynamic cytoskeletal regulation of cell shape supp orts resilience of lymphatic endothelium. Nature. 2025 May\;641(8062):465- 475. doi: 10.1038/s41586-025-08724-6.\n\nPetkova M\, Kraft M\, Stritt S\, Martinez-Corral I\, Ortsäter H\, Vanlandewijck M\, Jakic B\, Baselga E\, Castillo SD\, Graupera M\, Betsholtz C\, Mäkinen T. Immune-interacting ly mphatic endothelial subtype at capillary terminals drives lymphatic malfor mation. J Exp Med. 2023 Apr 3\;220(4):e20220741. doi: 10.1084/jem.20220741 .\n\nHernández Vásquez MN\, Ulvmar MH\, González-Loyola A\, Kritikos I\ , Sun Y\, He L\, Halin C\, Petrova TV\, Mäkinen T. Transcription factor F OXP2 is a flow-induced regulator of collecting lymphatic vessels. EMBO J. 2021 Jun 15\;40(12):e107192. doi: 10.15252/embj.2020107192.\n\nMartinez-Co rral I\, Zhang Y\, Petkova M\, Ortsäter H\, Sjöberg S\, Castillo SD\, Br ouillard P\, Libbrecht L\, Saur D\, Graupera M\, Alitalo K\, Boon L\, Vikk ula M\, Mäkinen T. Blockade of VEGF-C signaling inhibits lymphatic malfor mations driven by oncogenic PIK3CA mutation. Nat Commun. 2020 Jun 8\;11(1) :2869. doi: 10.1038/s41467-020-16496-y. ATTACH;FMTTYPE=image/jpeg:https://biocityturku.fi/wp-content/uploads/ISS-T humbnailMakinen-03022026.png CATEGORIES:BiocityTurku events,Other events END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:STANDARD DTSTART:20251026T030000 TZOFFSETFROM:+0300 TZOFFSETTO:+0200 TZNAME:EET END:STANDARD END:VTIMEZONE END:VCALENDAR