BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN BEGIN:VEVENT UID:534@biocityturku.fi DTSTART;TZID=Europe/Helsinki:20231205T140000 DTEND;TZID=Europe/Helsinki:20231205T150000 DTSTAMP:20231127T094634Z URL:https://biocityturku.fi/events/immunology-seminar-eliisa-kekalainen/ SUMMARY:Immunology Seminar: Eliisa Kekäläinen DESCRIPTION:December 5th at 14:00\nVirtual event\n\nEliisa Kekäläinen\, T ranslational Immunology Research Program\, University of Helsinki &\; H US Diagnostic Center\, Helsinki University Hospital\nThe thymus\, thymopoi esis\, and thymic pathologies - relevant only in rare diseases?\nHost: Rii tta Lahesmaa ( rilahes@utu.fi )\n\nRegister latest Dec 4th at https://link .webropolsurveys.com/S/A9FF7AB612EC68AE\n\nImmunology seminar series is jo intly organised by the Finnish Society for Immunology\, InFLAMES Flagship and Turku Bioscience. For further information contact Anne Lahdenperä  ( ankahy@utu.fi ) or Riitta Lahesmaa ( rilahes@utu.fi )\, University of Turk u.\n\n \;\n\nEliisa Kekäläinen\, M.D. Ph.D.\, research group is base d at the University of Helsinki\, and is part of Translational Immunology Research Program. Eliisa Kekäläinen has wide interest in immunodeficienc y diagnostics and immunological tolerance. Her research focuses especially on the primary immunological organ the thymus. She is interested in how e .g. common viral infections and hematopoietic stem cell transplantation af fect thymus function\, how they could better measure thymopoiesis in clini cal situations\, and what kind of pathological processes in the thymus lea d to immunodysregulation in autoimmune diseases such as myasthenia gravis. Eliisa Kekäläinen works also at the HUS Diagnostic Center Clinical Micr obiology and Immunology (Helsinki University Hospital) where she mainly fo cuses on immunodeficiency laboratory diagnostics.\n\n \;\n\nSelected p ublications\n\nIlonen I\, Kytö V\, Kekäläinen E. Health Consequences of Thymus Removal in Adults. N Engl J Med. 2023 Nov 2\;389(18):1725-1726. do i: 10.1056/NEJMc2310640. PMID: 37913515.\n\nMyllynen C\, Sarkkinen J\, Atu la S\, Tienari P\, Kekäläinen E\, Laakso SM. A skewed ratio of free ligh t chains is more common in patients with late-onset than early-onset myast henia gravis. Immunol Lett. 2023 Aug\;260:81-88. doi: 10.1016/j.imlet.2023 .07.001. Epub 2023 Jul 4. PMID: 37414259.\n\nSarkkinen J\, Dunkel J\, Tuul asvaara A\, Huuskonen A\, Atula S\, Kekäläinen E\, Laakso SM. Ectopic ge rminal centers in the thymus accurately predict prognosis of myasthenia gr avis after thymectomy. Mod Pathol. 2022 Sep\;35(9):1168-1174. doi: 10.1038 /s41379-022-01070-2. Epub 2022 Mar 25. PMID: 35338262\; PMCID: PMC9424113. \n\nHetemäki I\, Kaustio M\, Kinnunen M\, Heikkilä N\, Keskitalo S\, … \,  Otava U\, Syrjänen J\, Saarela J\, Varjosalo M\, Kekäläinen E. Los s-of-function mutation in IKZF2 leads to immunodeficiency with dysregulate d germinal center reactions and reduction of MAIT cells. Sci Immunol. 2021 Nov 26\;6(65):eabe3454. doi: 10.1126/sciimmunol.abe3454. Epub 2021 Nov 26 . PMID: 34826260.14 ATTACH;FMTTYPE=image/jpeg:https://biocityturku.fi/wp-content/uploads/2023/ 11/general-molecules-thumbnail.jpg CATEGORIES:Other events END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:STANDARD DTSTART:20231029T030000 TZOFFSETFROM:+0300 TZOFFSETTO:+0200 TZNAME:EET END:STANDARD END:VTIMEZONE END:VCALENDAR