BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN BEGIN:VEVENT UID:748@biocityturku.fi DTSTART;TZID=Europe/Helsinki:20251211T120000 DTEND;TZID=Europe/Helsinki:20251211T130000 DTSTAMP:20251117T111055Z URL:https://biocityturku.fi/events/frontiers-of-science-prof-marco-demaria / SUMMARY:Frontiers of Science: Prof. Marco Demaria DESCRIPTION:11th December at 12:00\nOnsite event\nin Presidentti auditorium \, BioCity\nAutumn 2025 program\n\nProf. Marco Demaria\, University of Gro ningen\, The Netherlands\nHeterogeneity in cellular senescence: from mecha nisms to interventions\n\nHost: Gennady Yegutkin (genyeg@utu.fi)\n\n \ ;\n\nNo coffee nor sandwiches this time\, but lunch instead!\n\nBioCity Tu rku wants to thank all its people from the great 2025 which was full of gr eat events and good vibes. After Prof. Demaria’s talk there is lunch ser ved in BioCity 1st floor lobby. There are seats for 150 first ones to regi ster and we hope many of you can make it.\n\nRegister here: https://link.w ebropolsurveys.com/S/A24F2F06197BBA30\n\n \;\n\nDr Demaria is an assoc iate professor in Cellular Ageing and his research is focused towards iden tifying novel mechanisms and biomarkers associated to senescent cells. His laboratory has also a strong interest to characterize the pro-disease fun ctions of senescent cells induced during aging and by anti-cancer therapie s. A major goal is to exploit these findings for the development of rejuve nating interventions. In 2018 he co-founded a start-up company\, Cleara Bi otech\, devoted to develop anti-senescence drugs.\n\n \;\n\nSelected p ublications\n\nPharmacological CDK4/6 inhibition promotes vulnerability to lysosomotropic agents in breast cancer. Nehme J\, Maassen S\, Bravaccini S\, Zanoni M\, Gianni C\, De Giorgi U\, Soto-Gamez A\, Altulea A\, Gheorgh e T\, Wang B\, Demaria M. EMBO J. 2025 Feb 10\n\nGuidelines for minimal in formation on cellular senescence experimentation in vivo. Ogrodnik M\, Car los Acosta J\, Adams PD\, d'Adda di Fagagna F\, …\, Scharffetter-Kochane k K\, Sedivy JM\, Sikora E\, Witwer K\, von Zglinicki T\, Yun MH\, Grillar i J\, Demaria M. Cell. 2024 Aug 8\;187(16):4150-4175\n\nConverting cell de ath into senescence by PARP1 inhibition improves recovery from acute oxida tive injury. Nehme J\, Mesilmany L\, Varela-Eirin M\, Brandenburg S\, Altu lea A\, Lin Y\, Gaya da Costa M\, Seelen M\, Hillebrands JL\, van Goor H\, Saab R\, Akl H\, Prevarskaya N\, Farfariello V\, Demaria M.Nat Aging. 202 4 Jun\;4(6):771-782\n\nThe Quest to Define and Target Cellular Senescence in Cancer. Wang B\, Demaria M. Cancer Res. 2021 Dec 15\;81(24):6087-6089.\ n\n \;\n\nGeneral information\n\n You can download and save all the a utumn 2025 FoS-seminars to your calendar from here: https://seafile.utu.fi /d/44a70f80ac1e46a9ad0a/\n Registration is not needed\, participation lis t is circulated in the audience\n If you are a student and later wish to get a certificate of attendance from the Frontier of Science seminars\, pr int out the seminar diary and after the seminar ask the BioCity coordinato r to sign it https://seafile.utu.fi/d/44a70f80ac1e46a9ad0a/\n Please note that any audio or video recording of the seminars is strictly forbidden.\ n Autumn 2025 image credits to Kari Kaunisto: Sahlberg family collections \, Biodiversity unit\, University of Turku\n\n \; ATTACH;FMTTYPE=image/jpeg:https://biocityturku.fi/wp-content/uploads/demar ia-500px.jpg CATEGORIES:Frontiers of Science END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:STANDARD DTSTART:20251026T030000 TZOFFSETFROM:+0300 TZOFFSETTO:+0200 TZNAME:EET END:STANDARD END:VTIMEZONE END:VCALENDAR