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UID:441@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20191212T120000
DTEND;TZID=Europe/Helsinki:20191212T130000
DTSTAMP:20231013T063134Z
URL:https://biocityturku.fi/events/frontiers-of-science-mechanics-and-mech
 anisms-of-vascular-tissue-architecture-and-homeostasis/
SUMMARY:Frontiers of Science: Mechanics and mechanisms of vascular tissue a
 rchitecture and homeostasis
DESCRIPTION:Prof. Cecilia Sahlgren\, Subject of Cell Biology\, Åbo Akademi
  University\, Finland\; Department of Biomedical Engineering\; Eindhoven U
 niversity of Technology\, the Netherlands\nMechanics and mechanisms of vas
 cular tissue architecture and homeostasis\n\nHost: Jyrki Heino (jyheino@ut
 u.fi)\n\n&nbsp\;\n\nCecilia Sahlgren is a professor of cell biology and b
 iomedical engineering at Åbo Akademi University and Eindhoven University 
 of Technology. Her research focuses on the fundamental molecular mechanis
 ms guiding cell fate and cell organization in stem cell differentiation\, 
 tissue formation and disease.\n\nCecilia obtained her PhD at Åbo Akademi 
 University in 2003\, focusing on intermediate filaments as signaling media
 tors. During her postdoctoral work at Karolinska Institutet (Stockholm\, S
 weden) 2005-2008\, she studied the role of Notch signaling in hypoxia-rela
 ted cancer cell characteristics. She then returned to Finland to establish
  the Cell Fate Lab at the Turku Centre for Biotechnology focusing on Notch
  in cancer and stem cell differentiation. Together with her collaborators\
 , she also worked on developing nanoparticles to target Notch for cancer t
 herapy and modulation of cell differentiation.\n\nIn 2013\, she moved to t
 he Eindhoven University of Technology (TU/e\, the Netherlands)\, first as 
 an assistant professor and subsequently full professor in Biomedical Engin
 eering. At TU/e\, her group has created technological platforms\, such as 
 organ-on-chip devices\, to study cell fate decisions in the vasculature an
 d in tumors\, combined with computational modeling to predict Notch mechan
 osensitivity.\n\nIn 2016\, she returned to Finland to become professor of 
 cell biology at Åbo Akademi University. In 2017\, she was awarded an ERC 
 Consolidator Grant to investigate the interplay of mechanical forces and c
 ell signaling in the vasculature and to clarify their effects on blood ves
 sel architecture. Currently\, her interdisciplinary research group combine
 s cell biological techniques\, bioengineering and mathematical modeling to
  understand the signaling mechanisms controlling cell fate in stem cell di
 fferentiation and disease in order to generate new strategies for regenera
 tive medicine and cancer therapy.
CATEGORIES:BiocityTurku events
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TZID:Europe/Helsinki
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DTSTART:20191027T030000
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