BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN BEGIN:VEVENT UID:46@biocityturku.fi DTSTART;TZID=Europe/Helsinki:20231214T120000 DTEND;TZID=Europe/Helsinki:20231214T130000 DTSTAMP:20231127T093647Z URL:https://biocityturku.fi/events/frontiers-of-science-md-tuomas-tammela/ SUMMARY:Frontiers of Science and after-seminar lunch: MD Tuomas Tammela DESCRIPTION:December 14th at 12:00\nOn-site event\nPresidentti auditorium\n Autumn 2023 program\n\nMD Tuomas Tammela\, Sloan Kettering Institute\; Mem orial Sloan Kettering Cancer Center\, US\nFunctional interrogation of intr a-tumoral heterogeneity\nHost: Klaus Elenius (klaele@utu.fi)\n\nCoffee at 11:45!\n\nInstead of having a sandwich before the seminar\, BioCity Turku wants to thank all the people who have joined us to listen to the Frontier s of Science seminars during 2023\, and welcome you all for lunch! Let’s have a lunch all together in BioCity lobby after the seminar at 13:00!\n\ nAs always\, no need to register to the seminar\, but if you want to join for the lunch please register at latest 10 December: https://link.webropol surveys.com/S/6A9778FB474466DA\n\n \;\n\nThe Tammela lab is interested in understanding the remarkable phenotypic heterogeneity of cancer cells within tumors. We approach this question using a combination of sophistica ted genetically engineered mouse models\, single-cell approaches\, tracing and ablation of distinct tumor cell lineages\, CRISPR-mediated gene regul ation\, and advanced imaging techniques. We utilize the exceptional resour ces developed by our MSK collaborators\, such as organoids and xenografts\ , for the translation of our findings into new treatments for human cancer . Our goal is to discover pathways that drive distinct cellular phenotypes and to develop new therapeutic concepts aimed at reducing cellular hetero geneity in tumors.\n\n \;\n\nSelected publications\n\nM Kim\, M Panagi otakopoulou\, C Chen\, SB Ruiz\, K Ganesh\, T Tammela\, ...\, 2023. Micro- engineering and nano-engineering approaches to investigate tumour ecosyste ms. Nature Reviews Cancer\, 1-19\n\nSR Torborg\, Z Li\, JE Chan\, T Tammel a. 2022. Cellular and molecular mechanisms of plasticity in cancer. Trends in Cancer 8 (9)\, 735-746\n\nMarjanovic ND\, Hofree M\, Chan JE\, … \, Rekhtman N\, Massion PP\, Poirier JT\, Mazutis L\, Li R\, Lee JH\, Amon A\ , Rudin CM\, Jacks T\, Regev A\, Tammela T. (2020). Emergence of a High-Pl asticity Cell State during Lung Cancer Evolution. Cancer Cell\, 38(2):229- 246\n\n \;\n\nGeneral information\n\n You can download and save all t he autumn 2023 FoS-seminars to your calendar from here: https://seafile.ut u.fi/d/44a70f80ac1e46a9ad0a/\n Registration is not needed\, participation list is circulated in the audience\n If you are a student and later wish to get a certificate of attendance from the Frontier of Science seminars\ , print out the seminar diary and after the seminar ask the BioCity coordi nator to sign it https://seafile.utu.fi/d/44a70f80ac1e46a9ad0a/\n Please note that any audio or video recording of the seminars is strictly forbidd en.\n Autumn 2023 FoS image credits to Anna-Mari Haapanen-Saaristo: Part of anoxia study of Eutardigrade species Macrobiotus Ripperi labelled with commercial fluorescent dyes\, image acquired on 3i CSU-W1 Spinning disk wi th 40x objective\n\n \;\n\n \; ATTACH;FMTTYPE=image/jpeg:https://biocityturku.fi/wp-content/uploads/2023/ 08/fos2023autumn_400px-nelio1.webp CATEGORIES:BiocityTurku events,Frontiers of Science END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:STANDARD DTSTART:20231029T030000 TZOFFSETFROM:+0300 TZOFFSETTO:+0200 TZNAME:EET END:STANDARD END:VTIMEZONE END:VCALENDAR