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UID:457@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20200206T120000
DTEND;TZID=Europe/Helsinki:20200206T130000
DTSTAMP:20231013T063210Z
URL:https://biocityturku.fi/events/frontiers-of-science-connecting-cell-me
 tabolism-with-dna-damage-response/
SUMMARY:Frontiers of Science: Connecting cell metabolism with DNA Damage Re
 sponse
DESCRIPTION:Prof. Marco Foiani\, IFOM\, The FIRC Institute of Molecular Onc
 ology\, Milan Italy &amp\; University of Milan\, Italy\nConnecting cell me
 tabolism with DNA Damage Response\n\nHost: Jukka Westermarck (jukwes@utu.f
 i)\n\nMarco Foiani is Professor of Molecular Biology at the University of 
 Milan and\, since 2009\, Scientific Director of IFOM\, an international ca
 ncer center that hosts 20 groups and 300 scientists. Prof. Foiani has stu
 died different cellular processes (translational\, chromosome replication\
 , DNA recombination\, DNA repair\, DNA topology\, transcription\, autophag
 y and nuclear envelope dynamics) and regulatory pathways (translational co
 ntrol\, cell cycle\, checkpoint\, sumo and ubiquitin pathways\, protein ac
 etylation\, gene gating) using a variety of approaches (biochemical\, gene
 tic\, imaging\, genomic\, molecular biology). His major contributions are 
 within the fields of chromosome dynamics and genome integrity. His work ha
 s contributed to elucidate the ATR and ATM-dependent checkpoint processes 
 controlling the interfaces between DNA replication\, recombination\, trans
 cription and DNA topology and preventing abnormal chromosome transitions.\
 n\n&nbsp\;\n\nReferences\n\nA model of DNA damage response activation at s
 talled replication forks by SPRTN.\nBruhn C\, Foiani M. Nat Commun. 2019 D
 ec 12\;10(1):5671\n\nCombination of Hypoglycemia and Metformin Impairs Tum
 or Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axi
 s.\nElgendy M\, Cirò M\, Hosseini A\, Weiszmann J\, Mazzarella L\, Ferrar
 i E\, Cazzoli R\, Curigliano G\, DeCensi A\, Bonanni B\, Budillon A\, Peli
 cci PG\, Janssens V\, Ogris M\, Baccarini M\, Lanfrancone L\, Weckwerth W\
 , Foiani M\, Minucci S. Cancer Cell. 2019 May 13\;35(5):798-815.e5\n\nAn E
 rror-Prone Polymerase in the Fight against Cancer.\nAchar YJ\, Foiani M. C
 ell. 2019 Mar 7\;176(6):1241-1243\n\nA Mad2-Mediated Translational Regulat
 ory Mechanism Promoting S-Phase Cyclin Synthesis Controls Origin Firing an
 d Survival to Replication Stress.\nGay S\, Piccini D\, Bruhn C\, Ricciardi
  S\, Soffientini P\, Carotenuto W\, Biffo S\, Foiani M. Mol Cell. 2018 May
  17\;70(4):628-638.e5\n\nPP2A Controls Genome Integrity by Integrating Nut
 rient-Sensing and Metabolic Pathways with the DNA Damage Response.\nFerrar
 i E\, Bruhn C\, Peretti M\, Cassani C\, Carotenuto WV\, Elgendy M\, Shubas
 si G\, Lucca C\, Bermejo R\, Varasi M\, Minucci S\, Longhese MP\, Foiani M
 . Mol Cell. 2017 Jul 20\;67(2):266-281.e4
CATEGORIES:BiocityTurku events
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TZID:Europe/Helsinki
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BEGIN:STANDARD
DTSTART:20191027T030000
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