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UID:444@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20191031T120000
DTEND;TZID=Europe/Helsinki:20191031T130000
DTSTAMP:20231013T063135Z
URL:https://biocityturku.fi/events/frontiers-od-science-lipid-metabolism-c
 onnecting-the-dots/
SUMMARY:Frontiers of Science: Lipid metabolism: connecting the dots
DESCRIPTION:Dr. Anne-Claude Gavin\, EMBL\, Heidelberg\, Germany\nLipid meta
 bolism: connecting the dots\n\nHost: Karolina Pavic (karolina.pavic@utu.fi
 )\n\nAnne-Claude Gavin studied biology/biochemistry at the University of G
 eneva\, achieving a PhD in biology under the supervision of Dr Sabine Scho
 rderet-Slatkine. She then moved to the European Molecular Biology Laborato
 ry in Heidelberg to study the biochemical mechanisms that regulate the pro
 gression of the cell cycle with Dr. Angel Nebreda. In 2000\, she joined th
 e biotech company Cellzome as a funding scientist and Director of the Mole
 cular and Cell Biology division\, applying systems biology approaches to c
 haracterize cellular networks involved in human pathologies. Since 2005\, 
 she has run her own group in the Structural and Computational Biology Unit
  at the European Molecular Biology Laboratory\, where she has pioneered no
 vel (bio)chemical methods to map cellular protein-lipid interaction networ
 ks. Her group has a strong research interest in the study of lipid metabol
 ism and the regulation of cellular membranes homeostasis\, with a special 
 focus on the machinery involved in the creation and maintenance of lipid g
 radients in eukaryotic cells\, and the study of mechanisms by which lipid 
 signatures are sensed and “read” by effector proteins. From 2019\, she
  leads her group at the CMU in Geneva\, as a Louis-Jeantet professor.\n\nS
 elected publications\nChiapparino A.\, Maeda K\, Turei D.\, Saez-Rodriguez
  J. and Gavin A.C. (2016). The orchestra of lipid-transfer proteins at the
  crossroads between metabolism and signalling. Prog. Lipid Res. 61\, 30-39
 .\n\nKöberlin M.S.\, Snijder B. ‡\, Heinz L.X.\, Baumann C.L.\, Fauster
  A.\, Vladimer G.I.\, Gavin A.C. and Superti-Furga G. (2015). A conserved 
 circular network of coregulated lipids modulates innate immune responses. 
 Cell 162\, 170-183.\n\nSaliba A.E.\, Vonkova I.\, Gavin A.C. (2015). The s
 ystematic analysis of protein–lipid interactions comes of age. Nat. Rev.
  Mol. Cell Biol. 16\, 753-761.\n\nSaliba A.E.*\, Vonkova I.*\, Ceschia S.\
 , Findlay G.M.\, Maeda K.\, Tischer C.\, Deghou S.\, van Noort V.\, Bork P
 .\, Pawson T.\, Ellenberg J. and Gavin A.C. (2014). A quantitative liposom
 e microarray to systematically characterize protein-lipid interactions. Na
 t. Methods 11\, 47-50.\n\nMaeda K.\, Poletto M.\, Chiapparino A. and Gavin
  A.C. (2014). A generic protocol for the purification and characterization
  of water-soluble protein–lipid complexes. Nat. Protoc. 9\, 2256-2266.\n
 \nMaeda K.\, Anand K.\, Chiapparino A.\, Kumar A.\, Poletto M.\, Kaksonen 
 M. and Gavin A.C. (2013). Interactome map uncovers phosphatidylserine tran
 sport by a family of oxysterol-binding proteins. Nature 501\, 257-261.\n\n
 Haberkant P.\, Raijmakers R.\, Wildwater M.\, Sachsenheimer T.\, Brügger 
 B.\, Maeda K.\, Houweling M.\, Gavin A.C.\, Schultz C.\, van Meer G.\, Hec
 k A.J. and Holthuis J.C. (2013). In vivo profiling and visualization of ce
 llular protein-lipid interactions using bifunctional fatty acids. Angew Ch
 em Int Ed Engl\, 52\, 4033-4038.
CATEGORIES:BiocityTurku events
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DTSTART:20191027T030000
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