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UID:914@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20260521T144500
DTEND;TZID=Europe/Helsinki:20260521T160000
DTSTAMP:20260417T112808Z
URL:https://biocityturku.fi/events/fican-west-guest-lecture/
SUMMARY:FICAN West Guest Lecture
DESCRIPTION:21st May at 14:45-16:00\nOnsite event\nin Säätiö lecture hal
 l\, Medisiina D\n\nCory Abate-Shen\, Ph.D.\, Columbia University\nHow circ
 ulating tumor cells find their way to distant sites — studying metastasi
 s in genetically engineered mouse models\n\nHost: Maria Sundvall (mahesu@u
 tu.fi)\n\nDr. Abate-Shen is an internationally recognized leader in genito
 urinary malignancies. Her innovative studies of genetically engineered mou
 se models for these cancers have led to the discovery of new biomarkers fo
 r early detection\, as well as advances in cancer prevention and treatment
 . Her studies of castration-resistant prostate cancer led to the identific
 ation of lineage plasticity as a key mechanism of drug resistance\, and he
 r investigations of prostate cancer metastasis have elucidated new mechani
 sms of metastasis as well as potential new targets for treating bone metas
 tasis.\n\nGet to know the speaker:\nAbate-Shen Lab | Department of Molecul
 ar Pharmacology and Therapeutics\nhttps://systemsbiology.columbia.edu/news
 /cory-abate-shen-elected-to-national-academy-of-sciences\n\n&nbsp\;\n\nSel
 ected publications\n\nArriaga JM\, Ronaldson-Bouchard K\, Picech F\, Nunes
  de Almeida F\, Afari S\, Chhouri H\, Vunjak-Novakovic G\, Abate-Shen C. I
 n vivo genome-wide CRISPR screening identifies CITED2 as a driver of prost
 ate cancer bone metastasis. Oncogene. 2024 Apr\;43(17):1303-1315.\n\nVasci
 aveo A\, Arriaga JM\, de Almeida FN\, …\, Rubin MA\, Shen MM\, Califano 
 A\, Abate-Shen C. OncoLoop: A Network-Based Precision Cancer Medicine Fram
 ework. Cancer Discov. 2023 Feb 6\;13(2):386-409.\n\nPapachristodoulou A\, 
 Rodriguez-Calero A\, …\, Mitrofanova A\, Dutta A\, Abate-Shen C. NKX3.1 
 Localization to Mitochondria Suppresses Prostate Cancer Initiation. Cancer
  Discov. 2021 Sep\;11(9):2316-2333.\n\nArriaga JM\, Panja S\, Alshalalfa M
 \, …\, Rabadan R\, Sims PA\, Mitrofanova A\, Abate-Shen C. A MYC and RAS
  co-activation signature in localized prostate cancer drives bone metastas
 is and castration resistance. Nat Cancer. 2020 Nov\;1(11):1082-1096.
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CATEGORIES:Other events
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