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UID:486@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20180921T140000
DTEND;TZID=Europe/Helsinki:20180921T150000
DTSTAMP:20231013T063550Z
URL:https://biocityturku.fi/events/complifesci-seminar-niemi-and-belogurov
 /
SUMMARY:CompLifeSci Seminar:  Jarmo Niemi and Georgiy Belogurov
DESCRIPTION:Dr. Jarmo Niemi\, Department of Biochemistry\, University of Tu
 rku: “Genome mining for the unknown – identifying biosynthetic genes f
 or C-nucleosides”\nand\nDr. Georgiy Belogurov\, Department of Biochemist
 ry\, University of Turku: “Unraveling the mechanism of RNA polymerase tr
 anslocation along the DNA”\n\nCoffee at 13:45\n\nDr. Jarmo Niemi started
  working with anthracycline biosynthesis in 1985\, in the Finnish pharmace
 utical company Leiras\, and has continued it since\, except for 1995-1998\
 , when working in a project concerning high-throughput screening methods f
 or peptide receptor agonists. His Ph. D. thesis was about "Hybrid Anthracy
 cline Antibiotics: Analysis and Application of Rhodomycin Biosynthetic Gen
 es from Streptomyces purpurascens". He now works in the Department of Bioc
 hemistry at the University of Turku\, with "Antibiotic Biosynthetic Engine
 ering"\, or ABE. The ABELAB wishes to promote research on microbial natura
 l products and contribute to the field with three major lines of investiga
 tions. We wish to conduct basic research on the biochemistry and biosynthe
 sis of natural products\, and understand at the molecular level how these 
 complex molecules are made. This requires a multidisciplinary approach usi
 ng genomics and bioinformatics\, molecular biology and structural biology 
 to provide detailed answers to the research questions. One key to the succ
 ess of natural products has been the incredible diversity of metabolites t
 hat Streptomyces are able to produce\, which has helped them to survive in
  a competitive ecological niche. In order to understand how these molecule
 s have come into existence in the first place\, we have conducted several 
 studies on the evolution of secondary metabolism using phylogenetic analys
 es and protein engineering.\n\nDr. Georgi Belogurov obtained Master of Sci
 ence in chemistry degree from the Department of Chemistry Lomonosov Moscow
  State University\, Moscow\, Russia in 1997. He then moved to the Universi
 ty of Turku\, Turku\, Finland\, were he made PhD (1997-2005) in the resear
 ch team led by Prof. Reijo Lahti. Georgi’s PhD research was dedicated to
  studies of transmembrane cation transporters. He then moved to the Ohio S
 tate University\, Columbus\, Ohio\, USA to make his postdoc (2006-2009) in
  the research team led by Prof. Irina Artsimovitch. Georgi’s postdoctora
 l work was dedicated to studies of prokaryotic transcription and transcrip
 tion inhibitors. In 2009 Georgi returned to the University of Turku\, Depa
 rtment of Biochemistry to set up his own research team. Dr. Belogurov labo
 ratory studies the mechanistic aspect of prokaryotic and eukaryotic transc
 ription by biochemical and biophysical methods.\n\n&nbsp\;
CATEGORIES:BiocityTurku events
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TZID:Europe/Helsinki
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DTSTART:20180325T040000
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