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UID:736@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20250306T150000
DTEND;TZID=Europe/Helsinki:20250306T160000
DTSTAMP:20250225T133156Z
URL:https://biocityturku.fi/events/cellcom-seminar-voojis/
SUMMARY:CellCom Seminar: Voojis
DESCRIPTION:6th March at 15:00\nOnsite event\nin ÅA Farmaci Lecture Hall\,
  3rd floor\, BioCity\n\nProf. Marc Vooijs\, Maastricht University\, the Ne
 therlands\nUnlocking a New Regulatory Switch in NOTCH Signaling:  Decidin
 g Between Activation and Inactivation\n\nHost: Päivi Koskinen (paivi.kosk
 inen@utu.fi)\n\nCoffee\, tea and buns served at 14:45.\n\n&nbsp\;\n\nJoin 
 us for an inspiring seminar by Prof. Marc Vooijs\, whose research is foc
 used on mechanistic insight into signal transduction by NOTCH family prote
 ins and their context-dependent role in stem cells\, cancer development a
 nd treatment response with an emphasis on tumor microenvironment and hypox
 ia. He has alsoestablished patient-derived 3D cell models to study thera
 peutic resistance mechanisms under both normal and hypoxic conditions. 
 For more information: https://www.maastrolab.com/marc-vooijs-lab\n\n&nbsp
 \;\n\nSelected recent publications\n\nSánchez-Castillo A et al. Sertral
 ine/chloroquine combination therapy to target hypoxic and immunosuppressiv
 e serine/glycine synthesis-dependent glioblastomas. Oncogenesis 13\, 39\
 , 2024. DOI: 10.1038/s41389-024-00540-3\n\nHoosemans L\, Vooijs M\, Hoeb
 en A. Opportunities and challenges of small molecule inhibitors in gliobla
 stoma treatment: Lessons learned from clinical trials. Cancers 16\, 3021
 \, 2024. DOI: 10.3390/cancers16173021\n\nGiuranno L et al. Enhanced ra
 diation sensitivity\, decreased DNA damage repair\, and differentiation de
 fects in airway stem cells derived from patients with chronic obstructive 
 pulmonary disease. Stem Cells Transl Med 13\, 927-939\, 2024. DOI: 10
 .1093/stcltm/szae043\n\nHounjet J et al. The DMT1 isoform lacking the ir
 on-response element regulates normal and malignant hematopoiesis via NOTCH
  pathway activation. FEBS Lett 598\, 1506-1512\, 2024. DOI: 10.1002/1
 873-3468.14870
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CATEGORIES:Other events
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TZID:Europe/Helsinki
X-LIC-LOCATION:Europe/Helsinki
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DTSTART:20241027T030000
TZOFFSETFROM:+0300
TZOFFSETTO:+0200
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