BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//wp-events-plugin.com//7.2.3.1//EN
BEGIN:VEVENT
UID:693@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20241128T123000
DTEND;TZID=Europe/Helsinki:20241128T133000
DTSTAMP:20241125T091140Z
URL:https://biocityturku.fi/events/cellcom-seminar-prof-rachel-lennon/
SUMMARY:CellCom Seminar: Prof. Rachel Lennon
DESCRIPTION:28th November at 12:30-13:30\nOnsite event\nin Biocity building
 \, Åbo Akademi 3rd floor Biochemistry seminar room\, A-side\n\nProf. Rach
 el Lennon\, Director of the Wellcome Trust Centre for Cell-Matrix Research
 \, University of Manchester\, UK\nToo much turnover - basement membrane dy
 namics in disease \n\nHost: Johanna Ivaska (johanna.ivaska@utu.fi)\n\nCoff
 ee and pulla will be served beforehand\, so please arrive a few minutes ea
 rlier. First come\, first served.\n\nProf. Lennon is available on Thursday
  for scientific discussions. If you would like to book a meeting with her\
 , please contact Johanna Ivaska (johanna.ivaska@utu.fi). Also\, Rachel wil
 l be Jasmin Kaivola's PhD opponent on Friday 29th of November in Calonia (
 Cal I auditorium) at 12.00.\n\n&nbsp\;\n\nUnderstanding mechanisms of glom
 erular disease\, the leading cause of kidney disease in adults and childre
 n. The glomerular capillary wall is a highly sophisticated filtration barr
 ier that comprises specialised endothelial cells\, the glomerular basement
  membrane and specialised epithelial cells known as podocytes. Basement me
 mbrane regulation is fundamentally required for barrier integrity. The Len
 non lab have developed proteomic methods to resolve the cell adhesion-matr
 ix interface and have interrogated ultrastructure using serial block-face 
 scanning electron microscopy. Using a combination of in vitro systems (glo
 merular cell coculture\, kidney organoids) and animal models (mouse\, zebr
 afish) they seek to understand mechanisms of glomerular barrier injury and
  repair.\n\n&nbsp\;\n\nSelected publications\n\nStark Z\, Byrne AB\, Samps
 on MG\, Lennon R\, Mallett AJ. A guide to gene-disease relationships in ne
 phrology. Nat Rev Nephrol. 2024 Oct 23. doi: 10.1038/s41581-024-00900-7.\n
 \nTian P\, Koudis NM\, Morais MRPT\, Pickard A\, Fresquet M\, Adamson A\, 
 Derby B\, Lennon R. Collagen IV assembly is influenced by fluid flow in ki
 dney cell-derived matrices. Cells Dev. 2024 Sep\;179:203923. doi:0.1016/j.
 cdev.2024.203923.\n\nChew C\, Brand OJ\, Yamamura T\, Lawless C\, Morais M
 RPT\, Zeef L\, Lin IH\, Howell G\, Lui S\, Lausecker F\, Jagger C\, Shaw T
 N\, Krishnan S\, McClure FA\, Bridgeman H\, Wemyss K\, Konkel JE\, Hussell
  T\, Lennon R. Kidney resident macrophages have distinct subsets and multi
 functional roles. Matrix Biol. 2024 Mar\;127:23-37. doi: 10.1016/j.matbio.
 2024.02.002.\n\nMorais MRPT\, Tian P\, O'cualain R\, Lawless C\, Lennon R.
  Protocol to characterize basement membranes during kidney development usi
 ng mass spectrometry-based label-free quantitative proteomics. STAR Protoc
 . 2023 Dec 15\;4(4):102741. doi: 10.1016/j.xpro.2023.102741.\n\nHewitt RJ\
 , Puttur F\, Gaboriau DCA\, Fercoq F\, Fresquet M\, Traves WJ\, Yates LL W
 alker SA\, Molyneaux PL\, Kemp SV\, Nicholson AG\, Rice A\, Roberts E\, Le
 nnon R\, Carlin LM\, Byrne AJ\, Maher TM\, Lloyd CM. Lung extracellular ma
 trix modulates KRT5+ basal cell activity in pulmonary fibrosis. Nat Commun
 . 2023 Sep 27\;14(1):6039. doi: 10.1038/s41467-023-41621-y.
ATTACH;FMTTYPE=image/jpeg:https://biocityturku.fi/wp-content/uploads/CellC
 om-thumbnail.jpg
CATEGORIES:Other events
END:VEVENT
BEGIN:VTIMEZONE
TZID:Europe/Helsinki
X-LIC-LOCATION:Europe/Helsinki
BEGIN:STANDARD
DTSTART:20241027T030000
TZOFFSETFROM:+0300
TZOFFSETTO:+0200
TZNAME:EET
END:STANDARD
END:VTIMEZONE
END:VCALENDAR