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UID:816@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20250925T160000
DTEND;TZID=Europe/Helsinki:20250925T170000
DTSTAMP:20250918T082239Z
URL:https://biocityturku.fi/events/cellcom-seminar-andersson/
SUMMARY:CellCom Seminar: Andersson
DESCRIPTION:25th September at 16:00\nOnsite event\nin Auditorium Biologi\, 
 BioCity 2nd floor\n\nAssoc. Prof. Emma Andersson\, Karolinska Institute\, 
 Sweden\nTitle TBA\n\nHost: Cecilia Sahlgren (cecilia.sahlgren@abo.fi)\n\nC
 offee\, tea and buns served at 15:45\n\n&nbsp\;\n\nJoin us for an inspirin
 g seminar by Assoc. Prof. Emma Andersson. Dr. Andersson is a group leader 
 at the Department of Cell and Molecular Biology\, Karolinska Institute\, S
 weden. Her research focuses on the molecular mechanisms that guide the acq
 uisition of cell identity and organ architecture\, as well as how genetic 
 mutations lead to developmental defects. Her lab has developed several nov
 el molecular and biological tools to study RNA interference\, genetic dise
 ase (i.e.\, Alagille Syndrome)\, and organ system-specific lineage segrega
 tion. The Andersson Lab has made seminal discoveries relating to the molec
 ular mechanisms by which missense mutations in the Notch ligand Jagged1 le
 ad to morphological and functional defects in the liver\, vasculature\, an
 d the organ of Corti. Most recently\, they have uncovered how ectodermal t
 issues compartmentalize during development by combining genetic manipulati
 on of ectodermal progenitors in single-cell resolution with next-generatio
 n sequencing.\n\n&nbsp\;\n\nSelected publications\n\nde Haan et al.\, 2025
 \, “Ectoderm barcoding reveals neural and cochlear compartmentalization
 ” Science\n\nKosek et al.\, 2025\, Mapping effective microRNA pairing 
 beyond the seed using abasic modifications” Nucleic Acids Research\n\nM
 asek et al.\, 2024\, "Jag1 Insufficiency Alters Liver Fibrosis via T Cell 
 and Hepatocyte Differentiation Defects”\, EMBO Molecular Medicine\n\nde
  Haan et al.\, 2024\, “Jag1 represses Notch activation in lateral suppor
 ting cells and inhibits an outer hair cell fate in the medial compartment 
 of the developing cochlea” Development\n\nHankeova et al.\, 2022\, “
 Sex differences and risk factors for bleeding in Alagille syndrome”\, E
 MBO Molecular Medicine\n\nMangold et al.\, 2022\, “Murine neural plate t
 argeting by in utero nano-injection (NEPTUNE)”\, JoVE\n\nAndersson et a
 l.\, 2018\, “Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 
 Missense Mutations” Gastroenterology
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CATEGORIES:Other events
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TZID:Europe/Helsinki
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DTSTART:20250330T040000
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