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UID:655@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20241002T120000
DTEND;TZID=Europe/Helsinki:20241002T130000
DTSTAMP:20240923T085858Z
URL:https://biocityturku.fi/events/biocity-turku-guest-seminar-prof-makoto
 -suematsu/
SUMMARY:BioCity Turku Guest Seminar: Prof. Makoto Suematsu
DESCRIPTION:2nd October at 12:00\nOnsite event\nin Presidentti auditorium\,
  BioCity\n\nProf. Makoto Suematsu\, Keio University WPI-Bio2Q Research Cen
 ter\, Japan\nImaging metabolomics in humanized experimental platforms: Tra
 nslation to control cancer and neurodegenerative diseases\n\nHost: Bilal A
 ndrabi (sbaand@utu.fi)\n\nCoffee and sandwich at 11:45. First come first s
 erved!\n\n&nbsp\;\n\nImaging metabolomics provides multi-dimensional imagi
 ng information and includes imaging mass spectroscopy (IMS)\, surface-enha
 nced Raman spectroscopy (SERS) and magnetic resonance imaging and spectros
 copy (MRI/MRS). Two-dimensional visualization of small molecular metabolit
 es in cancer or ischemic damages by IMS and SERS require rapid frozen prot
 ocols to get meaningful interpretation in experimental medicine. We have u
 tilized super-immunodeficient NOG mice which allow engraftment of patient-
 derived cells or tissues to examine alterations in metabolic systems in vi
 vo by IMS or SERS (1-4). These techniques also benefit clinical applicatio
 n of needle-biopsied or post-operative frozen tissue to predict prognosis 
 of solid cancers (3\, 4). We have recently set up imaging metabolomics tec
 hnology to examine development of patient-derived cancer cells or neural d
 isease models in mice or common marmoset\, a non-human primate (5-7): Amon
 g them\, ultra-high field MRI (UHF-MRI) which enables to chase time histor
 y of spatio-temporal alterations in disease regions without euthanasia. I 
 would like to introduce the “humanized” experimental platforms and to 
 discuss how to apply these methods for future collaboration.\n\n&nbsp\;\n\
 nSelected publications\n\nKubo A\, et al. Antioxidants (2023)\nParas M\, e
 t al. Science (2024)\nYamamoto T\, et al. Cancer Research (2024)\nSato K\,
  et al. Lab Animal (2024)\n\n&nbsp\;\n\nBioCity Turku Guest Seminars are F
 rontiers of Science -level events with world-famous scientists giving the 
 talks. The speakers are distinguished scientists in their own field of res
 earch and they invoke interest among the wide audience. This BioCity Turku
  Guest Seminar is organized by BioCity Turku\, Turku Bioscience Centre and
  InFLAMES Flagship.\n\n&nbsp\;
ATTACH;FMTTYPE=image/jpeg:https://biocityturku.fi/wp-content/uploads/sumem
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CATEGORIES:BiocityTurku events
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