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UID:174@biocityturku.fi
DTSTART;TZID=Europe/Helsinki:20191107T141500
DTEND;TZID=Europe/Helsinki:20191107T150000
DTSTAMP:20231013T060739Z
URL:https://biocityturku.fi/events/biocity-guest-seminar-neuropilin-1-is-a
 -novel-target-for-snake-venoms-with-distinct-functions-on-different-types-
 of-vasculature/
SUMMARY:BioCity Guest seminar: Neuropilin-1 is a novel target for snake ven
 oms with distinct functions on different types of vasculature
DESCRIPTION:Prof. Johannes Eble\, University of Münster\, Germany\nNeuropi
 lin-1 is a novel target for snake venoms with distinct functions on differ
 ent types of vasculature.\n\nHost: Jyrki Heino (jyrki.heino@utu.fi)\n\nCof
 fee/tea served at 14:00\n\nDr. Johannes Eble is Professor of Biochemistry 
 and the Head of the Institute of Physiological Chemistry and Pathobiochemi
 stry at the University of Münster\, Germany. His research is focused on c
 ollagen- and laminin-binding integrins\, especially in the vasculature sys
 tem. The integrin-mediated interaction of cells with extracellular matrix 
 is of great importance for vasculature development and is often altered in
  pathological conditions such as inflammation and tumor formation. Profess
 or Eble's laboratory also studies how naturally occurring integrin inhibit
 ors could be translated into medical practices. Professor Eble has publish
 ed nearly 150 research articles.\n\nSelected recent publications\nOliveira
 \, L.S.\; Estevão-Costa\, M.I.\; Alvarenga\, V.G.\; Vivas-Ruiz\, D.E.\; Y
 arleque\, A.\; Lima\, A.M.\; Cavaco\, A.\; Eble\, J.A.\; Sanchez\, E.F. At
 roxlysin-III\, A Metalloproteinase from the Venom of the Peruvian Pit Vipe
 r Snake Bothrops atrox (Jergón) Induces Glycoprotein VI Shedding and Im
 pairs Platelet Function. Molecules 2019\, 24\, 3489.\n\nLima\, A.M.\, C
 avaco\, A.M.\, Fraga-Silva\, R.A.\, Eble\, J.A.\, Stergiopulos\, N. From P
 atients to Platelets and Back Again: Pharmacological Approaches to Glycopr
 otein VI\, a Thrilling Antithrombotic Target with Minor Bleeding Risks. Th
 romb Haemost. 2019. doi: 10.1055/s-0039-1695770.\n\nNiland S\, Eble JA. Ne
 uropilins in the Context of Tumor Vasculature. Int J Mol Sci. 2019\;20(3)
 :639. doi:10.3390/ijms20030639\n\nRezaei\, M.\, Cavaco\, A.M.\, Seebach\, 
 J.\, Niland\, S.\, Zimmermann\, J.\, Hanschmann\, EM.\, Hallmann\, R.\, He
 rmann Schillers H. and Eble\, JA. Signals of the Neuropilin-1–MET Axis a
 nd Cues of Mechanical Force Exertion Converge to Elicit Inflammatory Activ
 ation in Coherent Endothelial Cells. J Immunol 2019\, 202 (5) 1559-1572\; 
 DOI: https://doi.org/10.4049/jimmunol.1801346
CATEGORIES:BiocityTurku events
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TZID:Europe/Helsinki
X-LIC-LOCATION:Europe/Helsinki
BEGIN:STANDARD
DTSTART:20191027T030000
TZOFFSETFROM:+0300
TZOFFSETTO:+0200
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