Past Events
#February
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
February 7th at 15:00
Hybrid event
Lauren 1 – Medisiina D / Zoom
Sanna Iivanainen, Oulu University Hospital & University of Oulu
The prognostic role of peripheral blood inflammatory markers in advanced cancer patients treated with immune checkpoint inhibitors.
Gabriela Martínez Chacón, Åbo Academi University
Targeting M1-ubiquitination in inflammation-induced cancer
Zoom Meeting ID: 692 0798 1823
Passcode: 646152
Cancer Research Seminars are jointly organized by Turku Cancer Research Society (TCRS), FICAN West and Cancer Research Unit/UTU
“Cancer Research Seminar: Iivanainen and Martínez Chacón”February 7th at 15:00
Hybrid event
Lauren 1 – Medisiina D / Zoom
Sanna Iivanainen, Oulu University Hospital & University of Oulu
The prognostic role of peripheral blood inflammatory markers in advanced cancer patients treated with immune checkpoint inhibitors.
Gabriela Martínez Chacón, Åbo Academi University
Targeting M1-ubiquitination in inflammation-induced cancer
Zoom Meeting ID: 692 0798 1823
Passcode: 646152
Cancer Research Seminars are jointly organized by Turku Cancer Research Society (TCRS), FICAN West and Cancer Research Unit/UTU
February 7th at 14:00 – 15:00 (Finland time)
Virtual event
Luke O’Neill, Trinity College Dublin:
Adventures in Immunometabolism Research
Host: Riitta Lahesmaa (rilahes@utu.fi )
Registration latest February 6th at: https://link.webropolsurveys.com/S/C196B12841386EFF
Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience. For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.
Luke O’Neill is Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute at Trinity College Dublin, Ireland. He is a world expert on innate immunity and inflammation. His main research interests include Toll-like receptors, Inflammasomes and Immunometabolism. He is listed by Thompson Reuters/ Clarivates in the top 1% of immunologists in the world, based on citations per paper. Professor O’Neill is co-founder of Sitryx, which aims to develop new medicines for inflammatory diseases. Another company he co-founded, Inflazome was recently acquired by Roche.
He was awarded the Royal Dublin Society / Irish Times Boyle Medal for scientific excellence, the Royal Irish Academy Gold Medal for Life Sciences, The Society for Leukocyte Biology (SLB) Dolph O. Adams award, the European Federation of Immunology Societies Medal, the Milstein Award of the International Cytokine and Interferon Society and the Landsteiner Award from the Austrian Academy of Sciences. He is a member of the Royal Irish Academy, EMBO (European Molecular Biology Organisation) and a Fellow of the Royal Society.
References
Ryan DG, O’Neill LAJ Krebs Cycle Reborn in Macrophage Immunometabolism. Annu Rev Immunol. 2020 Jan 27. doi: 10.1146/annurev-immunol-081619-104850
O’Neill LAJ, Netea MG. BCG-induced trained immunity: can it offer protection against COVID-19? Nat Rev Immunol. 2020 Jun;20(6):335-337. doi: 10.1038/s41577-020-0337-y.
Hooftman A, Angiari S, Hester S, Corcoran SE, Runtsch MC, Ling C, Ruzek MC, Slivka PF, McGettrick AF, Banahan K, Hughes MM, Irvine AD, Fischer R, O’Neill LAJ. The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation. Cell Metab. 2020 Sep 1;32(3):468-478.e7. doi: 10.1016/j.cmet.2020.07.016.
Runtsch MC, Angiari S, Hooftman A, Wadhwa R, Zhang Y, Zheng Y, Spina JS, Ruzek MC, Argiriadi MA, McGettrick AF, Mendez RS, Zotta A, Peace CG, Walsh A, Chirillo R, Hams E, Fallon PG, Jayamaran R, Dua K, Brown AC, Kim RY, Horvat JC, Hansbro PM, Wang C, O’Neill LAJ.Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages. Cell Metab. 2022 Mar 1;34(3):487-501.e8. doi: 10.1016/j.cmet.2022.02.002.
Hooftman A, O’Neill LAJ.Nanoparticle asymmetry shapes an immune response. Nature. 2022 Jan;601(7893):323-325. doi: 10.1038/d41586-021-03806-7.
“Immunology Seminar: O’Neill”
February 7th at 14:00 – 15:00 (Finland time)
Virtual event
Luke O’Neill, Trinity College Dublin:
Adventures in Immunometabolism Research
Host: Riitta Lahesmaa (rilahes@utu.fi )
Registration latest February 6th at: https://link.webropolsurveys.com/S/C196B12841386EFF
Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience. For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.
Luke O’Neill is Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute at Trinity College Dublin, Ireland. He is a world expert on innate immunity and inflammation. His main research interests include Toll-like receptors, Inflammasomes and Immunometabolism. He is listed by Thompson Reuters/ Clarivates in the top 1% of immunologists in the world, based on citations per paper. Professor O’Neill is co-founder of Sitryx, which aims to develop new medicines for inflammatory diseases. Another company he co-founded, Inflazome was recently acquired by Roche.
He was awarded the Royal Dublin Society / Irish Times Boyle Medal for scientific excellence, the Royal Irish Academy Gold Medal for Life Sciences, The Society for Leukocyte Biology (SLB) Dolph O. Adams award, the European Federation of Immunology Societies Medal, the Milstein Award of the International Cytokine and Interferon Society and the Landsteiner Award from the Austrian Academy of Sciences. He is a member of the Royal Irish Academy, EMBO (European Molecular Biology Organisation) and a Fellow of the Royal Society.
References
Ryan DG, O’Neill LAJ Krebs Cycle Reborn in Macrophage Immunometabolism. Annu Rev Immunol. 2020 Jan 27. doi: 10.1146/annurev-immunol-081619-104850
O’Neill LAJ, Netea MG. BCG-induced trained immunity: can it offer protection against COVID-19? Nat Rev Immunol. 2020 Jun;20(6):335-337. doi: 10.1038/s41577-020-0337-y.
Hooftman A, Angiari S, Hester S, Corcoran SE, Runtsch MC, Ling C, Ruzek MC, Slivka PF, McGettrick AF, Banahan K, Hughes MM, Irvine AD, Fischer R, O’Neill LAJ. The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation. Cell Metab. 2020 Sep 1;32(3):468-478.e7. doi: 10.1016/j.cmet.2020.07.016.
Runtsch MC, Angiari S, Hooftman A, Wadhwa R, Zhang Y, Zheng Y, Spina JS, Ruzek MC, Argiriadi MA, McGettrick AF, Mendez RS, Zotta A, Peace CG, Walsh A, Chirillo R, Hams E, Fallon PG, Jayamaran R, Dua K, Brown AC, Kim RY, Horvat JC, Hansbro PM, Wang C, O’Neill LAJ.Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages. Cell Metab. 2022 Mar 1;34(3):487-501.e8. doi: 10.1016/j.cmet.2022.02.002.
Hooftman A, O’Neill LAJ.Nanoparticle asymmetry shapes an immune response. Nature. 2022 Jan;601(7893):323-325. doi: 10.1038/d41586-021-03806-7.
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
February 1st at 11:15
Hybrid event
Lauren 1 / Zoom
Spring 2023 program
Jukka Hytönen
Lyme borreliosis: a comprehensive approach
Zoom: https://utu.zoom.us/j/67311220029
“Infections and Immunity Seminar: Hytönen”February 1st at 11:15
Hybrid event
Lauren 1 / Zoom
Spring 2023 program
Jukka Hytönen
Lyme borreliosis: a comprehensive approach
#January
January 27th, time tba
Virtual event
Matthieu Bourgery, University of Turku
Small RNAs in skeletal tissue homeostasis and fracture healing
Tapio Lönnberg, University of Turku
Single-cell and spatially resolved sequencing
Chair: Kamila Pulawska
https://utu.zoom.us/j/62415869446
“IPP Seminar: Bourgery and Lönnberg”January 27th, time tba
Virtual event
Matthieu Bourgery, University of Turku
Small RNAs in skeletal tissue homeostasis and fracture healing
Tapio Lönnberg, University of Turku
Single-cell and spatially resolved sequencing
Chair: Kamila Pulawska
January 26th at 12:00
On-site event
Visiting Centre Joki
Welcome to the InFLAMES Research Flagship’s Corporate Corner titled Immunoprofiling and Immunodrug development.
In the event, you will hear the latest news of immunoprofiling and immunodrug development from company and research representatives. We have a great list of speakers from InFLAMES, Genomill, Auria Services, Aurlide, Orion, Misvik Biology, FICAN West, Valo Therapeutics and The Finnish Research Impact Foundation. In the end, the panel debate will discuss the promotion of industrial and academic cooperation.
The event starts with lunch at 11:45 and there is time for networking after the official programme at 16:00.
Hosts of the event are Professor Riitta Lahesmaa, Turku Bioscience Centre, University of Turku and Professor of Practice Timo Veromaa, University of Turku
Take a look at the preliminary program
“InFLAMES Corporate Corner”January 26th at 12:00
On-site event
Visiting Centre Joki
Welcome to the InFLAMES Research Flagship’s Corporate Corner titled Immunoprofiling and Immunodrug development.
In the event, you will hear the latest news of immunoprofiling and immunodrug development from company and research representatives. We have a great list of speakers from InFLAMES, Genomill, Auria Services, Aurlide, Orion, Misvik Biology, FICAN West, Valo Therapeutics and The Finnish Research Impact Foundation. In the end, the panel debate will discuss the promotion of industrial and academic cooperation.
The event starts with lunch at 11:45 and there is time for networking after the official programme at 16:00.
Hosts of the event are Professor Riitta Lahesmaa, Turku Bioscience Centre, University of Turku and Professor of Practice Timo Veromaa, University of Turku
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
January 25th at 12:00
On-site event
Medisiina D, Säätiö lecture hall
LIFE is part of the University of Turku thematic research profile Health, Diagnostics and Drug Development, funded by the Academy of Finland. LIFE focuses on multigenerational health pathways for lifelong health. It has high scientific and public health importance and an innovative strategy to identify novel methods for early prediction, treatment and prevention of major non-communicable diseases that pose the highest public health burden globally.
Join us in January to meet the new tenure track professors and learn about the selected highlights of LIFE infrastructure!
Click here to register: https://link.webropolsurveys.com/S/8EB654DD2451D2FC
Programme
12.00 Lunch in Tiedonkolu (between Majakkahospital and Medisiina D)
12.45 Vice Dean Markus Juonala – Opening words
13.00 Associate Professor Georgi Belogurov
13.20 Senior Research Fellow Otto Kauko
13.40 Associate Professor in Internal Medicine Tuomas Kiviniemi
14.00 Associate Professor in Surgery Peter Boström
14.20 Coffee and networking break
14.45 Introduction to LIFE research infrastructures
- Single Cell Omics – Senior Research Fellow Tapio Lönnberg
- Biostatistics – Biostatistician Terhi Kolari
- Centre for Population Health – Professor Olli Raitakari/Associate Professor Linnea Karlsson
15.15 Keynote lecture – Professor Jeroen Bax Turku PET Centre and Leiden University Medical Center
16.00 Discussion and the event ends
Welcome!
This event is organised in collaboration with Faculty of Medicine, Faculty of Technology, Turku Bioscience Centre and Turku PET Centre.
“Research Faculty meets LIFE!”January 25th at 12:00
On-site event
Medisiina D, Säätiö lecture hall
LIFE is part of the University of Turku thematic research profile Health, Diagnostics and Drug Development, funded by the Academy of Finland. LIFE focuses on multigenerational health pathways for lifelong health. It has high scientific and public health importance and an innovative strategy to identify novel methods for early prediction, treatment and prevention of major non-communicable diseases that pose the highest public health burden globally.
Join us in January to meet the new tenure track professors and learn about the selected highlights of LIFE infrastructure!
Click here to register: https://link.webropolsurveys.com/S/8EB654DD2451D2FC
Programme
12.00 Lunch in Tiedonkolu (between Majakkahospital and Medisiina D)
12.45 Vice Dean Markus Juonala – Opening words
13.00 Associate Professor Georgi Belogurov
13.20 Senior Research Fellow Otto Kauko
13.40 Associate Professor in Internal Medicine Tuomas Kiviniemi
14.00 Associate Professor in Surgery Peter Boström
14.20 Coffee and networking break
14.45 Introduction to LIFE research infrastructures
- Single Cell Omics – Senior Research Fellow Tapio Lönnberg
- Biostatistics – Biostatistician Terhi Kolari
- Centre for Population Health – Professor Olli Raitakari/Associate Professor Linnea Karlsson
15.15 Keynote lecture – Professor Jeroen Bax Turku PET Centre and Leiden University Medical Center
16.00 Discussion and the event ends
Welcome!
This event is organised in collaboration with Faculty of Medicine, Faculty of Technology, Turku Bioscience Centre and Turku PET Centre.
Mitoosi, Medisiina D, Turku
January 25th at 11:15
Hybrid event
Mitoosi and Meioosi / Zoom
Alex-Mikael Barkoff (He), title TBA
Henrik Elenius (Salmi), title TBA
Organized live at Medisiina D and via Zoom: https://utu.zoom.us/j/69915597198
The purpose of the seminar series is to give dissertation researchers and young researchers the opportunity to present their research and its results. At the same time, researchers have the opportunity to practice their presentation skills and receive feedback on their research. This series of seminars has a long tradition and dates back to the time of Mikro and has now been continued here on the premises of Medisiina D with a slightly wider coverage. The last day of the seminar series is reserved for the so-called Young Scientist progress report presentations, where slightly younger researchers can present for example their Master’s thesis research.
You are mostly welcome to come follow the seminars and to support the prospects of our unit of Infections and Immunity! In case of any questions, please contact the organizers Natalie nattom@utu.fi or Heidi: heidi.kunnasranta@utu.fi.
“Prospects of Infections and Immunity: Barkoff and Elenius”January 25th at 11:15
Hybrid event
Mitoosi and Meioosi / Zoom
Alex-Mikael Barkoff (He), title TBA
Henrik Elenius (Salmi), title TBA
Organized live at Medisiina D and via Zoom: https://utu.zoom.us/j/69915597198
The purpose of the seminar series is to give dissertation researchers and young researchers the opportunity to present their research and its results. At the same time, researchers have the opportunity to practice their presentation skills and receive feedback on their research. This series of seminars has a long tradition and dates back to the time of Mikro and has now been continued here on the premises of Medisiina D with a slightly wider coverage. The last day of the seminar series is reserved for the so-called Young Scientist progress report presentations, where slightly younger researchers can present for example their Master’s thesis research.
You are mostly welcome to come follow the seminars and to support the prospects of our unit of Infections and Immunity! In case of any questions, please contact the organizers Natalie nattom@utu.fi or Heidi: heidi.kunnasranta@utu.fi.
Aurum, Argentum auditorium, Henrikinkatu 2, Turku
January 24th at 10:00-17:00
Hybrid event
Argentum auditorium, Aurum / Zoom
Flyer
This one day seminar will address sustainability, featuring biofuels, energy storage, solar cells and carbon dioxide fixation. Participation is free but registration is mandatory (https://tinyurl.com/SusSolChem). A Zoom link for on-line participation is provided with registration. Participants are invited to present their work and compete for the best poster prize.
The speakers include:
Reko Leino (ÅA) Opening Words
Timo Repo (UH) Fixation of carbon dioxide for added-value materials
Liji Sobhana (MetGen) METNIN™ Lignin refining technology for sustainable bio-based products’
Jan-Henrik Smått (ÅA) Solar cells (surface and sol-gel chemistry)
Tapio Salmi (ÅA) Small molecule, catalysis & biofuel
More information
https://www.rsc.org/events/detail/75392/sustainable-solutions
and detailed program for the event
https://biocityturku.fi/wp-content/uploads/2023/01/RSC_seminar_24012023_RMx.pdf
The event has been organized by the Royal Society of Chemistry-Finland Local section and Åbo Akademi
“Sustainable Solutions in Chemical Sciences”January 24th at 10:00-17:00
Hybrid event
Argentum auditorium, Aurum / Zoom
Flyer
This one day seminar will address sustainability, featuring biofuels, energy storage, solar cells and carbon dioxide fixation. Participation is free but registration is mandatory (https://tinyurl.com/SusSolChem). A Zoom link for on-line participation is provided with registration. Participants are invited to present their work and compete for the best poster prize.
The speakers include:
Reko Leino (ÅA) Opening Words
Timo Repo (UH) Fixation of carbon dioxide for added-value materials
Liji Sobhana (MetGen) METNIN™ Lignin refining technology for sustainable bio-based products’
Jan-Henrik Smått (ÅA) Solar cells (surface and sol-gel chemistry)
Tapio Salmi (ÅA) Small molecule, catalysis & biofuel
More information
https://www.rsc.org/events/detail/75392/sustainable-solutions
and detailed program for the event
https://biocityturku.fi/wp-content/uploads/2023/01/RSC_seminar_24012023_RMx.pdf
The event has been organized by the Royal Society of Chemistry-Finland Local section and Åbo Akademi
#December
December 16th at 13:00
Virtual event in Zoom
Autumn 2022 program
Mari Lehti
Late Chromatoid Body Protein TSSK2 Associates with EIF3A in Mouse Elongating Spermatids
Maria Sundvall, University of Turku
Introduction of the Cancer Research Unit at the Institute of Biomedicine & SUMO pathway as a therapeutic target in cancer
Chair/concluding remarks: Donata Ponikwicka-Tyszko
https://utu.zoom.us/j/64196971456
Bimonthly Integrative Physiology and Pharmacology (IPP) seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks. IPP seminar series is organized and coordinated by Juho-Antti Mäkelä (jasmak@utu.fi) and Noora Kotaja (nookot@utu.fi).
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T-Hospital, Haartman Lecture Hall, Savitehtaankatu 1, Turku
December 13th at 15:30
On-site event
Haartman Hall, T-hospital, TYKS
Flyer
15.30 Ilmo Leivo, Professor of Pathology (emeritus), Faculty of Medicine, University of Turku
16.15 Hanna Taipaleenmäki, Professor of Musculoskeletal Oncology, Faculty of Medicine, Ludwig-Maximilians-University (LMU) Munich
17.00 The winner of the PhD thesis of the year award
17.15 Discussion and closing
17.30 Dinner
20.00 The end of the Seminar afternoon
Register at latest December 5th
https://link.webropolsurveys.com/S/A18F612C54AA859F
Only a limited number (60) of registrations will be accepted for the dinner using the first come, first serve principle. If you need to cancel your participation for the dinner, please, inform mertor@utu.fi immediately. All registrants for dinner will be contacted by email during the week 49.
Sponsors: Bristol Myers Squibb and Sirpa & Markku Jalkanen Foundation
December 13th at 14:00
Virtual event
Luke O’Neill, Trinity College Dublin
Adventures in Immunometabolism research
Host: Riitta Lahesmaa (rilahes@utu.fi)
Registration latest December 12th at:
https://link.webropolsurveys.com/S/C196B12841386EFF
Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience. For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.
Luke O’Neill is Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute at Trinity College Dublin, Ireland. He is a world expert on innate immunity and inflammation. His main research interests include Toll-like receptors, Inflammasomes and Immunometabolism. He is listed by Thompson Reuters/ Clarivates in the top 1% of immunologists in the world, based on citations per paper. Professor O’Neill is co-founder of Sitryx, which aims to develop new medicines for inflammatory diseases. Another company he co-founded, Inflazome was recently acquired by Roche.
He was awarded the Royal Dublin Society / Irish Times Boyle Medal for scientific excellence, the Royal Irish Academy Gold Medal for Life Sciences, The Society for Leukocyte Biology (SLB) Dolph O. Adams award, the European Federation of Immunology Societies Medal, the Milstein Award of the International Cytokine and Interferon Society and the Landsteiner Award from the Austrian Academy of Sciences. He is a member of the Royal Irish Academy, EMBO (European Molecular Biology Organisation) and a Fellow of the Royal Society.
References
Ryan DG, O’Neill LAJ Krebs Cycle Reborn in Macrophage Immunometabolism. Annu Rev Immunol. 2020 Jan 27. doi: 10.1146/annurev-immunol-081619-104850
O’Neill LAJ, Netea MG. BCG-induced trained immunity: can it offer protection against COVID-19? Nat Rev Immunol. 2020 Jun;20(6):335-337. doi: 10.1038/s41577-020-0337-y.
Hooftman A, Angiari S, Hester S, Corcoran SE, Runtsch MC, Ling C, Ruzek MC, Slivka PF, McGettrick AF, Banahan K, Hughes MM, Irvine AD, Fischer R, O’Neill LAJ. The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation. Cell Metab. 2020 Sep 1;32(3):468-478.e7. doi: 10.1016/j.cmet.2020.07.016.
Runtsch MC, Angiari S, Hooftman A, Wadhwa R, Zhang Y, Zheng Y, Spina JS, Ruzek MC, Argiriadi MA, McGettrick AF, Mendez RS, Zotta A, Peace CG, Walsh A, Chirillo R, Hams E, Fallon PG, Jayamaran R, Dua K, Brown AC, Kim RY, Horvat JC, Hansbro PM, Wang C, O’Neill LAJ.Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages. Cell Metab. 2022 Mar 1;34(3):487-501.e8. doi: 10.1016/j.cmet.2022.02.002.
Hooftman A, O’Neill LAJ.Nanoparticle asymmetry shapes an immune response. Nature. 2022 Jan;601(7893):323-325. doi: 10.1038/d41586-021-03806-7.
December 12th at 09:00
Virtual event
The universities in Turku launched in autumn 2021 a joint webinar series focusing on technology and sustainable development. Aboa Tech Talks will highlight new technologies and innovative technological research that can offer solutions to the complex global challenges of our time.
The sixth Aboa Tech Talks – Batteries Enabling a Sustainable Future webinar is open to everyone interested, including representatives from industry, government, the third sector, researchers and students. UTU will moderate the event and the language is English.
Webinar will be recorded and made publicly available. The previous Aboa Tech Talks -recordings can be seen in Turku Tech Campus webpages (link below)
Program and Speakers
09.00 Yagut Allahverdiyeva-Rinne, UTU, Welcome and introduction
09.10 Pekka Peljo, UTU, Pathways towards designing flow batteries for sustainable stationary energy storage
09.30 Kirsi Jalkanen, Akkurate, Battery digitalization for remote diagnostics
09.50 Heikki Saariluoma, TUAS, Additive manufacturing of metallic thermal management components for Li-ion batteries
10.10 Johan Bobacka, ÅAU, From lithium to sodium-ion batteries
More information from Yagut Allahverdiyeva-Rinne (allahve@utu.fi) and Maija Lespinasse (miholm@utu.fi)
No registration needed – just join the webinar!
https://utu.zoom.us/j/65904291945
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December 2nd at 13:00
Virtual event in Zoom
Autumn 2022 program
Pekka Roivas
Inhibition of Cancerous PP2A Inhibitor Proteins – Novel Targets for Cancer Therapy
Arghavan Jahandideh
Molecular Imaging of Myocarditis and Inflammatory Cardiomyopathy
Chair: Marika Karikoski
https://utu.zoom.us/j/64196971456
The Integrative Physiology and Pharmacology (IPP) seminar series is organized and coordinated by Juho-Antti Mäkelä (jasmak@utu.fi) and Noora Kotaja (nookot@utu.fi). We would like to encourage everybody to contact us if you or your supervisees want to give a presentation to share a great scientific story with the rest of us. Feedback is also always welcome. Attending these seminars is a great opportunity to get to better know the people around you and what they are doing.
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#November
PharmaCity Auditorium, Itäinen Pitkäkatu 4B, Turku
The event is in Finnish only
23s Marraskuuta klo 12:00-18:00
Hybriditapahtuma
Pha1 luentosali, Pharmacity / ja Zoom
Ohjelmalehtinen
Lääkekeksintöjä Suomen Turusta maailmalle
Tervetuloa Turun yliopiston biolääketieteen laitoksen, Suomen farmakologiyhdistyksen ja Organonin järjestämään symposiumiin
ILMOITTAUTUMINEN paikanpäälle saapuville 16.11.2022 mennessä (rekisteröitymislinkki täällä)
ETÄOSALLISTUMINEN ilman ilmoittautumista Zoomissa (katso linkki täältä)
TIEDUSTELUT professori Ullamari Pesonen ullamari.pesonen@utu.fi, puh. 050-524 8959
Ohjelma
Pj. Sanna Janhunen
12.00 Lauri Kangas: Ura ja elämänkaari
12:20 Mika Scheinin: Biomarkkereita ja lääkevaikutuskohteita
12:40 Antti Haapalinna: Aika Orionilla
13:00 Olavi Pelkonen: Medipolar/Farmos yhteishankkeet
13:20 Pirkko Härkönen: Ospemifeeni-projektin varhaisvaiheet
13:40 KAHVI
Pj. Eriika Savontaus
14:20 Marcel van Duin: Organon and Forendo together
14:40 Matti Poutanen: Yliopisto-yritysyhteistyö lääkekehityksessä
15:00 Mia Bengström: Terveysalan yhteistyö Suomessa
15:20 Kalervo Väänänen: Lääkealan koulutus ja tutkimus Turussa
15:40 Ullamari Pesonen: Lääkekehityksen tulevaisuus Turussa ja maailmalla
16:00 SFY 2021 väitöskirjapalkinnon saajan esitys
16:20 Päätössanat 16.30 – 18.00 VIINIÄ JA JUUSTOJA
Alhopuro auditorium, Medisiina D, Kiinamyllynkatu 10, Turku
November 22nd at 11:00-17:00
On-site event
Medisiina D, Alhopuro-hall and lobby
Flyer
What happens when health, culture and technology meet?
This event will bring people together and enable true encounters between the campus experts, researchers and collaboration partners. The event will strengthen the Health Campus Turku ethos and collaboration ties and highlight the achievements and accomplishments of the year 2022. At the campus fair and open day, you can visit the laboratory and simulation facilities at Medisiina D, meet several life science companies showcasing their products and learn about the different ongoing projects at the three campuses: Health Campus, TechCampus and Culture Campus.
Our captivating guest speaker Hanna Meretoja will tell us about Narrative Agency as the glue connecting literature and well-being together. In her recently published novel, Elotulet, her own firsthand experiences are intertwined with philosophical reflections. She is a professor of comparative literature at the University of Turku. She has studied cultural narratives, philosophical connections of literature and storification of trauma and disease.
Program and registration (at latest 14 Novebmer):
https://www.healthcampusturku.fi/news/health-campus-goes-art-and-technology-22-11-2022/
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
November 21st at 15:00
On-site event
BioCity Presidentti auditorium
Welcome to join Immunology Centre’s Kick-off Seminar. It will be held at Biocity President auditorium 21 November at 15:00-17:00 with dinner at 17:00-19:00. The event is free of charge.
Registration (click ‘ilmoittaudu tapahtumaan’):
https://www.utu.fi/fi/ajankohtaista/tapahtumat/immunology-centre-kick-off-seminar
The Hospital District of Southwest Finland (VSSHP) has chosen the Turku Immunology Centre as its unit of excellence. The Centre, which was established at the end of 2021, was also selected to the Roadmap for Research Infrastructures of the University of Turku. The Turku Immunology Centre is a joint centre of the Faculty of Medicine and Turku Bioscience Centre of the University of Turku and the Hospital District of Southwest Finland. It is strongly connected to the InFLAMES Flagship.
More about the centre: https://immunologycentre.fi/
November 18th at 13:00
Virtual event in Zoom
Autumn 2022 program
Ali Benkherouf
Sleep and Hoppiness: Discovery and Pharmacological Characterization of GABA(A) Receptor Modulators from Humulus lupulus
Matthieu Bourgery
Small RNAs in Skeletal Tissue Homeostasis and Fracture Healing
Chair: Arttu Junnila
https://utu.zoom.us/j/64196971456
The Integrative Physiology and Pharmacology (IPP) seminar series is organized and coordinated by Juho-Antti Mäkelä (jasmak@utu.fi) and Noora Kotaja (nookot@utu.fi). We would like to encourage everybody to contact us if you or your supervisees want to give a presentation to share a great scientific story with the rest of us. Feedback is also always welcome. Attending these seminars is a great opportunity to get to better know the people around you and what they are doing.
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Mitoosi, Medisiina D, Turku
November 16th at 11:15
Hybrid event
Medisiina D Mitoosi / Zoom
Sanja Vanhatalo
The Microbiome in Appendicolith Appendicitis
Organized live at Medisiina D and via Zoom: https://utu.zoom.us/j/65468116085
The purpose of the seminar series is to give dissertation researchers and young researchers the opportunity to present their research and its results. At the same time, researchers have the opportunity to practice their presentation skills and receive feedback on their research. This series of seminars has a long tradition and dates back to the time of Mikro and has now been continued here on the premises of Medisiina D with a slightly wider coverage.
You are mostly welcome to come follow the seminars and to support the prospects of our unit of Infections and Immunity! In case of any questions, please contact Aapo Knuutila (aajukn@utu.fi)
“Prospects of Infections and Immunity”November 16th at 11:15
Hybrid event
Medisiina D Mitoosi / Zoom
Sanja Vanhatalo
The Microbiome in Appendicolith Appendicitis
Organized live at Medisiina D and via Zoom: https://utu.zoom.us/j/65468116085
The purpose of the seminar series is to give dissertation researchers and young researchers the opportunity to present their research and its results. At the same time, researchers have the opportunity to practice their presentation skills and receive feedback on their research. This series of seminars has a long tradition and dates back to the time of Mikro and has now been continued here on the premises of Medisiina D with a slightly wider coverage.
You are mostly welcome to come follow the seminars and to support the prospects of our unit of Infections and Immunity! In case of any questions, please contact Aapo Knuutila (aajukn@utu.fi)
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
November 11th at 09:00
On-site event
Arje Scheinin auditorium, Dentalia
Prof. Jochen Schwenk, KTH Stockholm, Sweden
The dynamic architecture of the circulating proteome in health and disease
Host: Urpo Lamminmäki (urplammi@utu.fi)
Dr. Jochen Schweck is a professor of translational proteomics in the School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH, Stockholm. He is the scientific director of the Affinity Proteomics unit at Science for Life Laboratory (SciLifeLab) and his research group is associated to the Human Protein Atlas project. He acts as a chairman of HUPO’s Human Plasma Proteome project. His research interests include e.g., affinity-based plasma proteomics, translational biomarker discovery, multiplex immunoassay development and biostatistics.
Selected recent publications
Wesolowska-Andersen et al., “Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals : An IMI DIRECT study,” CELL REPORTS MEDICINE, vol. 3, no. 1, 2022.
- Yang et al., “Genetic Landscape of the ACE2 Coronavirus Receptor,” Circulation, vol. 145, no. 18, s. 1398-1411, 2022
Wu et al., “Elevated circulating follistatin associates with an increased risk of type 2 diabetes,” Nature Communications, vol. 12, no. 1, 2021.
Roxhed et al., “Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2,” Nature Communications, vol. 12, no. 1, 2021.
Bar et al., “A reference map of potential determinants for the human serum metabolome,” Nature, vol. 588, no. 7836, s. 135-140, 2020.
Suhre, M. I. McCarthy och J. M. Schwenk, “Genetics meets proteomics : perspectives for large population-based studies,” Nature reviews genetics, 2020.
“InFLAMES Seminar: Schwenk”November 11th at 09:00
On-site event
Arje Scheinin auditorium, Dentalia
Prof. Jochen Schwenk, KTH Stockholm, Sweden
The dynamic architecture of the circulating proteome in health and disease
Host: Urpo Lamminmäki (urplammi@utu.fi)
Dr. Jochen Schweck is a professor of translational proteomics in the School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH, Stockholm. He is the scientific director of the Affinity Proteomics unit at Science for Life Laboratory (SciLifeLab) and his research group is associated to the Human Protein Atlas project. He acts as a chairman of HUPO’s Human Plasma Proteome project. His research interests include e.g., affinity-based plasma proteomics, translational biomarker discovery, multiplex immunoassay development and biostatistics.
Selected recent publications
Wesolowska-Andersen et al., “Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals : An IMI DIRECT study,” CELL REPORTS MEDICINE, vol. 3, no. 1, 2022.
- Yang et al., “Genetic Landscape of the ACE2 Coronavirus Receptor,” Circulation, vol. 145, no. 18, s. 1398-1411, 2022
Wu et al., “Elevated circulating follistatin associates with an increased risk of type 2 diabetes,” Nature Communications, vol. 12, no. 1, 2021.
Roxhed et al., “Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2,” Nature Communications, vol. 12, no. 1, 2021.
Bar et al., “A reference map of potential determinants for the human serum metabolome,” Nature, vol. 588, no. 7836, s. 135-140, 2020.
Suhre, M. I. McCarthy och J. M. Schwenk, “Genetics meets proteomics : perspectives for large population-based studies,” Nature reviews genetics, 2020.
Wikgren lecture room, BioCity 1st floor, Tykistökatu 6, Turku
November 8th at 10:15
On-site event
Auditorium Wikgren, BioCity ground floor
Martin Alexander López, University of Liège, Belgium
The interplay of the alternative NFkB signalling pathway and the circadian rhythm in liver homeostasis
Host: Eeva-Liisa Eskelinen (eeva-liisa.eskelinen@utu.fi)
November 4th at 13:00
Virtual event in Zoom
Autumn 2022 program
Kirsi Ketola, University of Eastern Finland
Neuronal Stem Cell-like Lineage Reprogramming in Prostate Cancer
Pekka Ruusuvuori, University of Turku
Ai-driven Analysis of Histopathology Images
Chair: Karoliina Kajander
https://utu.zoom.us/j/64196971456
The Integrative Physiology and Pharmacology (IPP) seminar series is organized and coordinated by Juho-Antti Mäkelä (jasmak@utu.fi) and Noora Kotaja (nookot@utu.fi). We would like to encourage everybody to contact us if you or your supervisees want to give a presentation to share a great scientific story with the rest of us. Feedback is also always welcome. Attending these seminars is a great opportunity to get to better know the people around you and what they are doing.
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November 4th at 09:00
Virtual event
Flyer
The universities in Turku launched in autumn 2021 a joint webinar series focusing on technology and sustainable development. Aboa Tech Talks will highlight new technologies and innovative technological research that can offer solutions to the complex global challenges of our time.
No need to register to the event, just join the Zoom!
https://aboakademi.zoom.us/j/62344281840
Aboa Tech Talks – Sustainable use of biomass
09:00 Welcome and introduction, Johan Bobacka (ÅA)
09:10 Novel materials from trees towards medical applications, Chunlin Xu (ÅA)
09:30 Unlocking the potential of algae for a sustainable bioproduction, Yagut Allahverdiyeva-Rinne (TY)
09:50 From biomass to biogas, Andreas Willfors (Novia)
10.10 Development and utilization of biocomposites and bioplastics, Liisa Lehtinen (TuAMK)
10:30 From waste to value – Biomass fractionation, Lari Vähäsalo (CH-Bioforce)
10:50 Discussion
11:00 End
Novemer 3rd at 15:00
Virtual event
Johanna Ivaska, FCI K. Albin Johansson Research Professor, University of Turku
Cancer cells crossing borders
Click here to join the meeting
Cancer Research Seminars are jointly organized by Turku Cancer Research Society TCRS, FICAN West and Cancer Research Unit/UTU
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
November 2nd at 15:00
On-site event
Säätiö lecture hall, Medisiina D
Lassi Liljeroos, Roche
Moving from academia to pharma industry: what’s different, what’s similar and is it for me?
This is the first lecture of Inside Industry lecture series. Join for a sneak peek into what working for the industry is really like, as told directly by experts in the field themselves. First up is Personalised healthcare and genome profiling partner from Roche, Lassi Liljeroos.
Coffee and baked goods are served before the seminar
November 1st at 14:00
Virtual event
Clarissa Campbell, Research Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM)
Reciprocal interactions between Metabolism and Immunity
Host: Riitta Lahesmaa (rilahes@utu.fi )
Registration at latest October 31st
https://link.webropolsurveys.com/S/93424EB9FFCA7C25
Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience. For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.
Clarissa Campbell studied Biology with a minor in Genetics at the Federal University of Rio de Janeiro (UFRJ) and subsequently earned a master’s degree from the Oswaldo Cruz Foundation (FIOCRUZ) investigating how bacterial molecules exert immunomodulatory effects on mammalian cells via nuclear receptors, a topic she would continue to explore throughout her career. She joined the Tri-Institutional Immunology and Microbial Pathogenesis Program at Weill Cornell Medical College in New York as a graduate student where she specialized in mucosal immunology and regulatory T (Treg) cell biology. After obtaining her PhD, Clarissa remained under the mentorship of Dr. Alexander Rudensky at Memorial Sloan Kettering Cancer Center to continue her work on host- commensal interactions and pursue broader scientific questions bridging the fields of immunology and metabolism. Her research has characterized a circuit whereby microbial metabolites including short-chain fatty acids and secondary bile acids facilitate the differentiation of peripherally induced Treg cells, which in turn suppress immune responses to colonization and preserve a niche for a group of intestinal bacteria. More recently, she found that a bile acid-sensing nuclear receptor contributes to the cell-intrinsic responsiveness of effector T cells to fasting. Clarissa Campbell joined CeMM as a principal investigator in July 2021. Her lab is interested in investigating how changes in microbial and organismal metabolism contribute to regulate immune cell function.
Selected papers
Michaels AJ, Campbell C, Bou-Puerto R, Rudensk AY. Nuclear receptor LXRβ controls fitness and functionality of activated T cells. J Exp Med 2021 Apr 5;218(4):e20201311.
Campbell C, Marchildon F, Michaels AJ, Takemoto N, van der Veeken J, Schizas M, Pritykin Y, Leslie CS, Intlekofer AM, Cohen P, Rudensky AY. FXR mediates T cell-intrinsic responses to reduced feeding during infection. Proc Natl Acad Sci USA. 2020 Dec 29;117(52):33446-33454.
Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin W-B, Guo C-J, Violante S, Ramos RJ, Cross JR, Kadaveru K, Hambor J, Rudensky AY. Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells. Nature. 2020 May;581(7809):475-479.
Campbell C, Dikiy S, Bhattarai SK, Chinen T, Matheis F, Calafiore M, Hoyos B, Hanash A, Mucida D, Bucci V, Rudensky AY. Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance. Immunity. 2018 Jun 19;48(6):1245-1257.e9.
Arpaia N, Campbell C, Fan X, Dikiy S, van der Veeken J, deRoos P, Liu H, Cross JR, Pfeffer K, Coffer PJ, Rudensky AY. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature. 2013 Dec 19;504(7480):451-5.
#October
Medisiina D, Lauren 2 lecture hall, Kiinamyllynkatu 10, Turku
October 28th at 15:00
On-site event
Medisiina D, Lauren 2
Tero Aittokallio, InFLAMES visiting professor
Predictive modelling of treatment responses in hematological malignancies
Professor Tero Aittokalllio is currently working as a group leader in Oslo University Hospital, Institute for Cancer Research and University of Oslo, Oslo Centre for Biostatistics and Epidemiology. He is also a Group Leader in Institute for Molecular Medicine Finland (FIMM), University of Helsinki. His group has expertise in integrating multi-omics profiling and clinical information from cancer patients using mathematical and statistical approaches such as machine learning and network modeling. Tero’s research profile can be found here: https://ous-research.no/aittokallio/
Selected publications
Zhao Z, Wang S, Zucknick M, Aittokallio T. Tissue-specific identification of multi-omics features for pan-cancer drug response prediction. iScience 2022;25:104767. doi: 10.1016/j.isci.2022.104767
Ianevski A, Giri AK, Aittokallio T. Fully-automated and ultra-fast cell-type identification using specific marker combinations from single-cell transcriptomic data. Nature Communications 2022; 13: 1246. http://doi.org/10.1038/s41467-022-28803-w.
Cichońska A, Ravikumar B, Allaway RJ, Wan F, Park S, Isayev O, Li S, Mason M, Lamb A, Tanoli Z, Jeon M, Kim S, Popova M, Capuzzi S, Zeng J, Dang K, Koytiger G, Kang J, Wells CI, Willson TM; IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium, Oprea TI, Schlessinger A, Drewry DH, Stolovitzky G, Wennerberg K, Guinney J, Aittokallio T. Crowdsourced mapping of unexplored target space of kinase inhibitors. Nature Communications 2021;12:3307. doi: 10.1038/s41467-021-23165-1.
Akimov Y, Bulanova D, Timonen S, Wennerberg K, Aittokallio T. Improved detection of differentially represented DNA barcodes for high-throughput clonal phenomics. Molecular Systems Biology 2020; 16: e9195. doi.org/10.15252/msb.20199195
Ianevski A, Lahtela J, Javarappa KK, Sergeev P, Ghimire BR, Gautam P, Vähä-Koskela M, Turunen L, Linnavirta N, Kuusanmäki H, Kontro M, Porkka K, Heckman CA, Mattila P, Wennerberg K, Giri AK, Aittokallio T. Patient-tailored design for selective co-inhibition of leukemic cell subpopulations. Science Advances 2020; 7: eabe4038, DOI: 10.1126 / sciadv.abe4038
JOKI Visitor Centre, Lemminkäisenkatu 12, Turku
October 24th at 12:00-16:00
on-site event
Visiting Centre Joki, Cave
Put your multidisciplinary hat on and be ready for a crash!
In this event Health, Diagnostics and Drug Development (HDDD) Thematic collaboration will introduce itself to Health Campus Turku, and vice versa. Come along for a fun and relaxed yet informative afternoon accompanied by a tasty menu. You get to meet researchers and experts from many different disciplines, expand your own network and quite possibly walk away with new ideas for collaboration.
In the key note speech, The online space is for humans – and so must be the data, we will dive head first into the world of data and learn why data is not just for engineers. Our captivating guest speaker, Katariina Kari, will share her expertese on data and knowledge graphs by telling us why it is essential to understand the language of our intended target audience when communicating online, whether internally or externally. Most of our work and communication today happens online, and growingly so. Why should we care about data and how does a more human friendly data serve our collaboration partners and internally, our organization. Katariina Kari is the lead ontologist at Inter IKEA Systems. Katariina holds a Master in Science and Master in Music specialising in semantic web and guiding humankind to the digital age. Katariina makes use of varied semantic web technologies to realise knowledge graphs across many domains, especially lifestyle and e-commerce.
Program
12.00 Lunch and opening of the event
Markus Juonala, Health Campus Turku research working group leader
Jyrki Heino, HDDD chair of executive committee
12.30 Key note speech
Katariina Kari, Lead Ontologist, Inter IKEA Systems B.V.
The online space is for humans – and so must be the data
13.00 Introducing Health Campus Turku
Leena Setälä, VSSHP Director of Development
What is Health Campus Turku – organisation and research
Janne Lahtiranta, TScP Network Manager
TERTTU Collaboration Service
14.00 Prime networking moment – don’t walk away empty handed!
Tuomas Riihimäki in piano, together with bubbles and snacks
14.30 Introducing Health, Diagnostics and Drug Development thematic collaboration
Jyrki Heino, HDDD chair of executive committee
Health Communication
Jukka Westermarck, Turku Bioscience Research Director
Clinical Disease Biomarkers
Niina Junttila, HDDD vice-chair of executive committee
New STN funded project: Right to belong
15.30 Wrap up – How can we benefit from each other, if at all?
Leena Setälä, VSSHP Director of Development
16.00 The event ends
Registration to the event is open until Monday 17 October
https://link.webropolsurveys.com/S/B4ED8AA50D87D56A
Please note that the registration is binding.
However, if you have to cancel you participation please inform Maija Lespinasse (miholm@utu.fi)
Thematics TeamUp is a continuous series of informal networking events for researchers and collaborators interested in the different topics. The networking events are hosted by the six thematic collaborations of the University of Turku.
https://www.utu.fi/en/research/thematic-collaborations-in-research/team-up
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October 24th–25th
hybrid event
Viikki Campus, Biocentre 2, Hall 2041, Helsinki / streaming
The Molecular Regulatory Networks of Life (R’Life) Academy Programme organizes its 3rd Annual Seminar on 25–26 October 2022 at Viikki Campus. The seminar will start at 12:00 on the first day and conclude by 14:00 on the second day. The themes of the seminar are connections between different levels of regulatory networks and implementing and combining new research methods. The event will be held in English.
Molecular Regulatory Networks of Life (R’Life) Academy Programme explores how various mechanisms create links between different parts of the genome and gene networks and how these links regulate life functions. The programme aims to yield key information on networks that regulate the function of cells, tissues, and individuals. The R’Life Academy Programme Annual Seminar provides an excellent possibility to hear about ongoing research in the programme.
In addition to presentations by R’Life reseachers, on the first seminar day, we will have a keynote presentation by Omer Bayraktar from Sanger Institute, Cambridge, UK and on the second day by Fernanda Pinheiro from Human Technopole, Italy.
We also invite all interested postgraduate students working in the field of molecular biology to attend the seminar and to bring a poster to the seminar to present their work. We encourage PhD students both working in the R’Life projects and in other research groups and projects to attend.
The seminar is open to everybody interested in molecular biology. Attending the seminar is free of charge and participants are expected to cover their own travel costs.
Please register at the latest by 17 October to attend the seminar and by 30 September if you are a postgraduate student bringing a poster.
https://www.lyyti.fi/reg/rlife2022
More information regarding the event
https://www.aka.fi/suomen-akatemian-toiminta/ajankohtaista/tapahtumat/rlife-academy-programme-annual-seminar/
October 24th–25th
hybrid event
Viikki Campus, Biocentre 2, Hall 2041, Helsinki / streaming
The Molecular Regulatory Networks of Life (R’Life) Academy Programme organizes its 3rd Annual Seminar on 25–26 October 2022 at Viikki Campus. The seminar will start at 12:00 on the first day and conclude by 14:00 on the second day. The themes of the seminar are connections between different levels of regulatory networks and implementing and combining new research methods. The event will be held in English.
Molecular Regulatory Networks of Life (R’Life) Academy Programme explores how various mechanisms create links between different parts of the genome and gene networks and how these links regulate life functions. The programme aims to yield key information on networks that regulate the function of cells, tissues, and individuals. The R’Life Academy Programme Annual Seminar provides an excellent possibility to hear about ongoing research in the programme.
In addition to presentations by R’Life reseachers, on the first seminar day, we will have a keynote presentation by Omer Bayraktar from Sanger Institute, Cambridge, UK and on the second day by Fernanda Pinheiro from Human Technopole, Italy.
We also invite all interested postgraduate students working in the field of molecular biology to attend the seminar and to bring a poster to the seminar to present their work. We encourage PhD students both working in the R’Life projects and in other research groups and projects to attend.
The seminar is open to everybody interested in molecular biology. Attending the seminar is free of charge and participants are expected to cover their own travel costs.
Please register at the latest by 17 October to attend the seminar and by 30 September if you are a postgraduate student bringing a poster.
https://www.lyyti.fi/reg/rlife2022
More information regarding the event
https://www.aka.fi/suomen-akatemian-toiminta/ajankohtaista/tapahtumat/rlife-academy-programme-annual-seminar/
October 21st at 13:00
Virtual event in Zoom
Autumn 2022 program
Maxwell Miner
Emerging Radiopharmaceuticals for PET Imaging Gliomas and 3D Printing Fillable Phantom Subjects
Konrad Patyra
Novel Molecular Mechanisms of Thyroid Disorders: From Human Diseases to Mouse Models
Chair: Milja Arponen
https://utu.zoom.us/j/64196971456
The Integrative Physiology and Pharmacology (IPP) seminar series is organized and coordinated by Juho-Antti Mäkelä (jasmak@utu.fi) and Noora Kotaja (nookot@utu.fi). We would like to encourage everybody to contact us if you or your supervisees want to give a presentation to share a great scientific story with the rest of us. Feedback is also always welcome. Attending these seminars is a great opportunity to get to better know the people around you and what they are doing.
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Alhopuro auditorium, Medisiina D, Kiinamyllynkatu 10, Turku
October 10th at 09:45
On-site event
Medisiina D, Alhopuro lecture hall
In October, Corporate Corner will explore and discover novel collaboration opportunities with Bayer Nordic. We will improve partnership awareness and inspire exchange between academia and industry. During the event, researchers can present their ideas, findings or technology to Bayer representatives for possible further collaboration. The event will be held in Medisiina D. Everyone interested is welcome to participate in the morning session to learn about Bayer interests and focus areas.
Program
Morning session – open for everyone registered to the event
Venue: Alhopuro lecture hall, Medisiina D, Kiinamyllynkatu 10
Moderator: Thomas Westerholm
9.45 Registration & Coffee
10.15 Welcome and Bayer introduction
Rector Jukka Kola, Bayer Nordic CEO Christiane Temminghoff
10.35 Bayer functional focus areas & needed competences
Tomi Penttilä, Manja Ahola, Tarja Jalava
11.15 Discussions on opportunities in University-Corporate Collaboration
Christiane Temminghoff/Jukka Kola, Manja Ahola/Reko Leino, Tomi Penttilä/Vesa Taatila
Parallel afternoon sessions
Medisiina D and Visitor and Innovation Centre Joki at Lemminkäisenkatu 12 B
- 00 – 16.00 One-on-One discussions and pitches of researchers with pre-selected topics in Medisiina D
- 00 – 15.00 Discussion about Bayer recruitment opportunities in Medisiina D
- 00 – 16.00 Pharma R&D Simulation Workshop in Joki
16:00 Event concludes
Register for the morning event and 1:1 discussions
More information about Bayer interest areas (pdf)
Important information about confidentiality and IPR (Word document)
More information on Corporate Corner
The deadline for registering for discussions is 12 September, but you can register for the morning session before 3 October.
October 7th at 14:00
Virtual event in Zoom
Autumn 2022 program
Changing career from Academy to Industry:
Suvi Ruohonen, Sanofi
Working in medical affairs in a global pharmaceutical company
Niina Saarinen-Aaltonen, Organon
Working as a scientist in a pharmaceutical company
Chair: Juho-Antti Mäkelä
https://utu.zoom.us/j/64196971456
The Integrative Physiology and Pharmacology (IPP) seminar series is organized and coordinated by Juho-Antti Mäkelä (jasmak@utu.fi) and Noora Kotaja (nookot@utu.fi). We would like to encourage everybody to contact us if you or your supervisees want to give a presentation to share a great scientific story with the rest of us. Feedback is also always welcome. Attending these seminars is a great opportunity to get to better know the people around you and what they are doing.
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Alhopuro auditorium, Medisiina D, Kiinamyllynkatu 10, Turku
October 4th at 15:00
Hybrid event
Alhopuro Hall, Medisiina D
Gautier Follain, University of Turku
A closer look at the extravasation step of circulating tumor cells
On-line participation link: https://utu.zoom.us/j/65087190064
Passcode: 020919
Meeting ID: 650 8719 0064
Cancer Research Seminars are jointly organized by Turku Cancer Research Society TCRS, FICAN West and Cancer Research Unit/UTU
October 4th at 14:00
Virtual event
William Agace, Lund University and Danish Technical University
Intestinal dendritic cell diversity and function
Medisiina D, Lauren 2 lecture hall, Kiinamyllynkatu 10, Turku
October 4th at 11:00
On-site event
Lauren 2, Medisiina D
Coffee, tea and sandwiches are served before the seminar
Aled Clayton, Cardiff University, UK
InFLAMES Visiting Professor career talk
InFLAMES also organizes an informal lunch meeting for early career scientists with Professor Clayton immediately after his career talk at 12 in Medisiina D Blokki 1. Please register separately for this event here: https://link.webropol.com/s/lunch-aled-clayton
Prof. Clayton established the first group focused on investigating the roles of extracellular vesicles (exosomes) in the UK. The group has published highly cited articles in relation to vesicles, their roles in subverting immune responses, in controlling the cancer microenvironment and as potential disease biomarkers. He has published some of the seminal articles of the EV field with a h-index of 45 (>18 000 citations).
He is interested in understanding the mechanisms by which vesicle biogenesis and secretion is controlled, and the impact such vesicles have on the development and progression of cancer; particularly focusing on prostate cancer. Developing tools and assays to quantify nano-vesicles in biological fluid specimens is also an important aspect of the group’s activities.
Although his main focus is in cancer biology, he collaborates broadly with researchers in Cardiff, including those in the schools of dentistry, engineering and optometry, and interacts with other Universities on aspects including cardiovascular disease, neurodegenerative diseases and other conditions that impact society in significant ways.
https://www.cardiff.ac.uk/people/view/122903-clayton-aled
https://scholar.google.co.uk/citations?user=pgDjFGcAAAAJ&hl=en
#September
September 28th at 15:00
Virtual event in Teams
Juha Klefström, PhD, FICAN Research Professor in Finnish Cancer Institute
Uncovering the full potential of patient-derived explant cultures – exploring human breast cancer biology, lethal MYC signaling, microenvironment and antitumor immunity at the bench
Join the seminar: Teams link
Regional cancer centers have jointly started new national seminar series, the FICAN seminars. The second FICAN Seminar is organized by FICAN South (Eteläinen syöpäkeskus in Finnish) and the speaker is FICAN Research professor Juha Klefström from Finnish Cancer Institute. The seminar is organised in Teams and is open to all interested in the topic.
Get to know the Speaker:
https://klefstromlab.com/home/juha-klefstrom/
Abstract
Our research focuses on therapeutic strategies aiming to exploit oncogene-induced vulnerabilities and we have had a long-term interest especially in the apoptotic function of MYC protein. Our group recently discovered a clinically applicable combination regimen, which shows a strong apoptotic activity selectively in MYC-high breast tumors in all preclinical models tested so far. My talk will cover our advances in translating the biological understanding of MYC biology into new type of therapeutic modalities to battle the breast cancer. A key asset in our research involves patient-derived explant culture models (PDEC) of breast cancer. We have pioneered the development of PDEC models and we have recently generated a whole family of PDEC models to explore for instance the biology of hormone receptor positive breast cancers, metastatic breast cancer microenvironment and drug resistance and possible ways to overcome. Furthermore, we have established a platform for PDECs with natural tumor infiltrating leukocytes to explore the immuno-oncology targeted drug responses. My talk will cover the latest developments in our work with PDEC models of breast cancer with specific focus on MYC-dependent signaling as a major cause of targetable vulnerabilities in breast cancer.
References
Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.
Lee JV, Housley F, Yau C, Nakagawa R, Winkler J, Anttila JM, Munne PM, Savelius M, Houlahan KE, Van de Mark D, Hemmati G, Hernandez GA, Zhang Y, Samson S, Baas C, Esserman LJ, van ‘t Veer LJ, Rugo HS, Curtis C, Klefström J, Matloubian M, Goga A.Nat Commun. 2022 Jun 27;13(1):3671. doi: 10.1038/s41467-022-31238-y.PMID: 35760778
Compressive stress-mediated p38 activation required for ERα + phenotype in breast cancer.
Munne PM, Martikainen L, Räty I, Bertula K, Nonappa, Ruuska J, Ala-Hongisto H, Peura A, Hollmann B, Euro L, Yavuz K, Patrikainen L, Salmela M, Pokki J, Kivento M, Väänänen J, Suomi T, Nevalaita L, Mutka M, Kovanen P, Leidenius M, Meretoja T, Hukkinen K, Monni O, Pouwels J, Sahu B, Mattson J, Joensuu H, Heikkilä P, Elo LL, Metcalfe C, Junttila MR, Ikkala O, Klefström J.Nat Commun. 2021 Nov 29;12(1):6967. doi: 10.1038/s41467-021-27220-9.PMID: 34845227 Free PMC article.
Sortilin-related receptor is a druggable therapeutic target in breast cancer.
Al-Akhrass H, Pietilä M, Lilja J, Vesilahti EM, Anttila JM, Haikala HM, Munne PM, Klefström J, Peuhu E, Ivaska J.Mol Oncol. 2022 Jan;16(1):116-129. doi: 10.1002/1878-0261.13106. Epub 2021 Oct 10.PMID: 34564954 Free article.
Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
Haikala HM, Anttila JM, Marques E, Raatikainen T, Ilander M, Hakanen H, Ala-Hongisto H, Savelius M, Balboa D, Von Eyss B, Eskelinen V, Munne P, Nieminen AI, Otonkoski T, Schüler J, Laajala TD, Aittokallio T, Sihto H, Mattson J, Heikkilä P, Leidenius M, Joensuu H, Mustjoki S, Kovanen P, Eilers M, Leverson JD, Klefström J.Nat Commun. 2019 Feb 6;10(1):620. doi: 10.1038/s41467-019-08541-2.PMID: 30728358 Free PMC article.
September 23rd at 13:00
Virtual event in Zoom
Autumn 2022 program
Ville Paakinaho, PhD, Adj. Prof, University of Eastern Finland
Transcription Factor Crosstalk in Cancers
Rogerio De Figueiredo, Asst. Prof., PhD, University of Turku
The Future of Immune Checkpoint Therapies
Chair and opening words: Ammar Ahmedani
https://utu.zoom.us/j/64196971456
The Integrative Physiology and Pharmacology (IPP) seminar series is organized and coordinated by Juho-Antti Mäkelä (jasmak@utu.fi) and Noora Kotaja (nookot@utu.fi). We would like to encourage everybody to contact us if you or your supervisees want to give a presentation to share a great scientific story with the rest of us. Feedback is also always welcome. Attending these seminars is a great opportunity to get to better know the people around you and what they are doing.
.
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
September 13th at 15:00
hybrid event
Medisiina D, Säätiö / Zoom
Jukka Westermarck, University of Turku
Translation of basic science findings to clinical use – Lessons from the sabbatical time in Milan
Welcome to the first Cancer Research Seminar of the fall season 2022! Cancer Research Special Seminar September the 13th, 2022, at 15-16:30, Medisiina D, first floor, Kiinamyllynkatu 10, Lecture room Säätiö “Translation of basic science findings to clinical use – Lessons from the sabbatical time in Milan” by Professor Jukka Westermarck, and discussion about the need and applications in Turku.
The seminar is arranged as a hybrid seminar.
Zoom link:
https://utu.zoom.us/j/67279196618
Meeting ID: 672 7919 6618
Passcode: 878028
Cancer Research Seminars are jointly organized by Turku Cancer Research Society and FICAN West
December 13th at 14:00
Virtual event
Luke O’Neill, Trinity College Dublin
Title tba
#June
Thursday June 6th
at 11-12
Säätiö-Sali (Medisiina D)
Professor Scott Allen from the University of Sheffield will be giving a lecture in Turku as a guest of InFLAMES. The lecture will be held on Thursday June 16th in Medisiina D Säätiö-Sali, Med1024 at 11 am. The topic of the lecture is Mechanisms of glial toxicity contributing to neuronal damage.
There will be coffee, tea and sandwiches served on-site. You can also participate online in Zoom.
https://utu.zoom.us/j/61101388191
About Professor Scott Allen:
Professor Scott Allen is a neuroscientist from the University of Sheffield. He has worked on charting the basic mechanisms leading to the neural cell destruction via glial activation. The process is an important factor for example in ALS disease.
“InFLAMES Guest Lecture by Professor Scott Allen”
Thursday June 6th
at 11-12
Säätiö-Sali (Medisiina D)
Professor Scott Allen from the University of Sheffield will be giving a lecture in Turku as a guest of InFLAMES. The lecture will be held on Thursday June 16th in Medisiina D Säätiö-Sali, Med1024 at 11 am. The topic of the lecture is Mechanisms of glial toxicity contributing to neuronal damage.
There will be coffee, tea and sandwiches served on-site. You can also participate online in Zoom.
https://utu.zoom.us/j/61101388191
About Professor Scott Allen:
Professor Scott Allen is a neuroscientist from the University of Sheffield. He has worked on charting the basic mechanisms leading to the neural cell destruction via glial activation. The process is an important factor for example in ALS disease.
June 10th at 12:00
Medisiina D lecture hall Lauren 2
https://utu.zoom.us/j/66116584353
Welcome to the InFLAMES Visiting Professor lecture by Professor Teng-Leong Chew! The lecture is held on Friday, June 10th at 14-15 in Medisiina D lecture hall Lauren 2. Coffee, tea and cookies are served on-site before the seminar.
It’s also possible to participate via Zoom:
https://utu.zoom.us/j/66116584353
Short biography of Professor Chew:
After obtaining a BS in Biochemistry at the University of Wisconsin-Madison, Teng-Leong Chew went to St. Louis University to pursue his PhD, where he worked to understand the role of myosin II regulation in endothelial cells. Realizing that conventional biochemical methods could not address the spatial and temporal regulation of signaling pathways inside the cell, Chew embarked on his postdoctoral research in the laboratory of Rex Chisholm by developing fluorescent biosensor to simultaneously monitor the enzymatic activity and localization pattern of myosin light chain kinase in vivo. Since then he has worked on multiple leading and directional positions, such as the director of the Center for Advanced Microscopy at Feinberg School of Medicine, Northwestern University.
Since 2014 Professor Chew has been the Director of Advanced Imaging Center (AIC), Howard Hughes Medical Institute, Janelia Research Campus), the leading institute in the world in the development of microscopy. He leads the effort in building the unique collaborative imaging center that serves as the gateway through which the wider scientific world can access Janelia’s cutting-edge microscopy capabilities. The AIC led by Dr Chew is an esteemed research centre in the world open to all researchers and the visiting research groups can use the instruments, cost-free. This infrastructure is not available anywhere else.
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
June 8th-10th
on-site event
BioCity, Presidentti auditorium
BioCity Turku research programme SmartBio is participating in arranging a three-day congress
The event will bring together excellent teams from academia and industry, and focuses on advances with cyanobacteria, micro-and macroalgae.
Registration, abstract submission and detailed program in
https://nas22.fi/
June 7th at 14:00
Virtual event
Spring 2022 program
Marko Salmi, University of Turku
The lymph node as a filter
Registration latest Jun 6 at: https://link.webropolsurveys.com/S/38514ADFC0B3B229
Zoom link and iCalendar invitation to join the online event will be sent to all registered participants one day before the event.
Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience.
For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.
Marko Salmi, MD, PhD, is currently Professor of Immunology at University of Turku. He also serves as Director of MediCity Research Laboratory, Director of Infection and Inflammation unit in Institute of Biomedicine and Vice-Director of InFLAMES Academy of Finland Flagship. Prof. Salmi’s research group studies myeloid cell differentiation, leukocyte migration and antigen transport in health and disease. The group has also analyzed the value of new biomarkers in inflammatory and malignant diseases using population and patient cohorts. Prof. Salmi has published >170 original research articles including senior-authorship papers in Immunity, Nature Immunology and Nature.
Selected publications
Rantakari P, Auvinen K, Jäppinen J, Kapraali M, Valtonen J, Karikoski M, Gerke H, , IIftakhar-E-Khuda I, Keuschnigg J, Umemoto E, Tohya K, Miyasaka M, Elima K, Jalkanen S, Salmi M. Plvap controls the entry of antigens to conduits and lymphocyte transmigration to parenchyma in the lymphatic sinus of lymph nodes. Nat Immunol 16:386-96, 2015.
Kähäri L, Fair-Mäkelä R, Auvinen K, Rantakari P, Jalkanen S, Ivaska J, Salmi M. Transcytosis route mediates rapid delivery of intact antibodies to draining lymph nodes. J Clin Invest. 129:3086-3102, 2019.
Logomo, Junakatu 8, Turku
June 7th–10th
Hybrid event
Logomo
The 21st International European Light Microscopy Initiative (ELMI) meeting is coming back in 2022 as an in-person meeting held in Turku, Finland. ELMI 2022 will be a hybrid event, and a subset of the program, including the scientific presentation, will also be available online.
Final registration deadline: 16 May 2022
Register here: https://elmi2022.eu/registration-and-prices
ELMI 2022 will update you on the latest light microscopy developments, research, techniques, and instrumentation. During the morning sessions, international leaders will give plenary lectures. During the afternoon sessions, company workshops will provide demos of the latest microscopy techniques and instruments. ELMI 2022 will continue the successful tradition of bringing together microscopy users, developers, core facility staff, and industry leaders by mixing high-quality scientific talks and posters with workshops and demos of the latest imaging technologies, not forgetting social activities. This year the ELMI gala diner will be held in Naantali, a nearby city part of the Finnish archipelago and home of the Moomin island. As with previous ELMI meetings, we will also organize the traditional academia versus industry football game as well as a satellite meeting dedicated to core facility staff.
Consult the ELMI website for more information regarding the ELMI.
We hope many of you will join us in Turku for ELMI 2022.
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
June 7th at 08:30
On-site event
Medisiina D, Lauren 1 and 2
Program
Many young researchers overlook that a PhD has a dual perspective:
- To do good research and
- To prepare you for your next career step whatever that might be. In this one-day career seminar, we aim at supporting you in seeing how you can prepare for your next career step, what the benefits are and how you can do it without taking your focus away from your research.
We will focus on increasing your understanding of the many skills you develop as a researcher, and how these are relevant both inside and outside of academia. You will hear speakers from different sectors discuss which skills are required in their areas, and you will work with mapping your own skill set. By the end of the day, you will hopefully have gained an awareness and understanding of the many important skills and experiences you develop as a young researcher, how these are highly useful and valued and in general understand how you can become a career-wise researcher. The day will be a mix of presentations and group work and coffee is included.
Registration is open until 30.5.2022 (23.59)
https://link.webropolsurveys.com/S/195EEF92BB2F8DDE
June 6th at 12:00
Medisiina D lecture hall Lauren 2
https://utu.zoom.us/j/64085843903
Welcome to the introductory lecture of InFLAMES Visiting Professor Teng-Leong Chew! The lecture is held on Monday, June 6th at 12-13 in Medisiina D lecture hall Lauren 2. Coffee, tea and cookies are served on-site before the seminar.
It’s also possible to participate via Zoom:
https://utu.zoom.us/j/64085843903
Short biography of Professor Chew:
After obtaining a BS in Biochemistry at the University of Wisconsin-Madison, Teng-Leong Chew went to St. Louis University to pursue his PhD, where he worked to understand the role of myosin II regulation in endothelial cells. Realizing that conventional biochemical methods could not address the spatial and temporal regulation of signaling pathways inside the cell, Chew embarked on his postdoctoral research in the laboratory of Rex Chisholm by developing fluorescent biosensor to simultaneously monitor the enzymatic activity and localization pattern of myosin light chain kinase in vivo. Since then he has worked on multiple leading and directional positions, such as the director of the Center for Advanced Microscopy at Feinberg School of Medicine, Northwestern University.
Since 2014 Professor Chew has been the Director of Advanced Imaging Center (AIC), Howard Hughes Medical Institute, Janelia Research Campus), the leading institute in the world in the development of microscopy. He leads the effort in building the unique collaborative imaging center that serves as the gateway through which the wider scientific world can access Janelia’s cutting-edge microscopy capabilities. The AIC led by Dr Chew is an esteemed research centre in the world open to all researchers and the visiting research groups can use the instruments, cost-free. This infrastructure is not available anywhere else.
#May
Auditorium Biology, BioCity 2nd floor, Turku
May 25th at 11:00-12:00
On-site event
Auditorium Biology, Biocity (2nd floor)
Asst. Prof. Tommaso Ristori, Eindhoven University of Technology
Computational modeling guides the research and control of angiogenesis
Host: Cecilia Sahlgren (cecilia.sahlgren@abo.fi)
Coffee, tea and pastries served at the start of the seminar
Dr. Ristori is an Assistant Professor in Biomedical Engineering at Eindhoven University of Technology, the Netherlands. His research is focused on computational modelling of angiogenesis for tissue engineering applications.
Achieving a full understanding and control of angiogenesis, the formation of new blood vessels from a pre-existing vasculature, is one of the key challenges to advance the field of tissue engineering. This process is regulated by several cross-talking cell signalling pathways, which vary over time and space. Perturbing their spatiotemporal dynamics is a promising recent trend in tissue engineering. Computational models can be a game-changer in this context; they can be combined with cell experiments to unravel the spatiotemporal interactions of different pathways and to optimize engineering techniques.
May 20th at 13:00
virtual event
Spring 2022 prorgram
Petteri Rinne, PhD, Adj.Prof
Untangling the role of melanocortin signaling in the heart
Pekka Taimen, Asst. Prof., MD, PhD, University of Turku
Nuclear lamins and dilated cardiomyopathy
Chair and concluding remarks: Noora Kotaja
Bimonthly IPP seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks.
Zoom link to join the seminar:
https://utu.zoom.us/s/68303022462
May 20th at 13:00
virtual event
Spring 2022 prorgram
Petteri Rinne, PhD, Adj.Prof
Untangling the role of melanocortin signaling in the heart
Pekka Taimen, Asst. Prof., MD, PhD, University of Turku
Nuclear lamins and dilated cardiomyopathy
Chair and concluding remarks: Noora Kotaja
Bimonthly IPP seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks.
Zoom link to join the seminar:
https://utu.zoom.us/s/68303022462
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
May 18th at 12:00
Hybrid event
Medisiina D, Lauren / Zoom
Welcome to join us for the early life environment and child development spring seminar by international researchers visiting the FinnBrain Birth Cohort Study. The seminar will take place on 18th of May, 2022 at 12 – 2 pm, Lauren auditorium, Medisiina D, Kiinanmyllynkatu 10, University of Turku.
The seminar can also be followed remotely: https://utu.zoom.us/j/61482726079
May 12th-13th
On-site event
Institute of Dentistry, Arje Scheinin Hall
We cordially invite you to attend the FINDOS symposium Inflammatory Conditions and their effects on Oral and General Health. We proudly present a versatile programme with great speakers and current topics. See the programme attached and at https://sites.utu.fi/findos-symposiums/findos-symposium-2022/
Participation in FINDOS Symposium 2022 is free of charge. Coffee and pastries are available during the coffee breaks. Conference lunch is not included. The symposium is organized only in person to facilitate networking. No hybrid nor recordings are available.
The deadline for registration is 28 April 2022. Register now!
https://link.webropolsurveys.com/S/3DDBBAFB7CE653B0
Digital poster exhibition
This year FINDOS Symposium digital poster session will be organized as “Read by title” presentations. All National FINDOS doctoral candidates and other researchers and research groups are invited to send their digital posters in PowerPoint presentation form that could be presented as “a read by title” presentation. The presentation will be viewable as a power point presentation on the spot on screen during the breaks. The presentations are running automatically on the screens but it is recommended that the researcher could be at the place on Thursday 12 May 2022 at 11.00-11.30 in Arje Schein lecture hall for questions and discussions with other researchers.
Instructions
The presentation should not include more than 3 slides.
The opening slide should display a straightforward title, name of the researcher and collaborators, affiliations and some attractive image. The objective, materials, and methods, results and conclusions should not exceed more than 250 words, and they should be presented in maximum of 2 slides.
Clinical patient cases can also be presented.
Submission of Posters (ppt) by 4 May 2022 to Coordinator Maiju Kannisto maiju.kannisto@utu.fi
We strongly encourage all study groups and researchers to present their studies in FINDOS Symposium!
If you want more information about the presentations, please contact Jaana Willberg jaana.willberg@utu.fi
Welcome!
“FINDOS-Turku Symposium”May 12th-13th
On-site event
Institute of Dentistry, Arje Scheinin Hall
We cordially invite you to attend the FINDOS symposium Inflammatory Conditions and their effects on Oral and General Health. We proudly present a versatile programme with great speakers and current topics. See the programme attached and at https://sites.utu.fi/findos-symposiums/findos-symposium-2022/
Participation in FINDOS Symposium 2022 is free of charge. Coffee and pastries are available during the coffee breaks. Conference lunch is not included. The symposium is organized only in person to facilitate networking. No hybrid nor recordings are available.
The deadline for registration is 28 April 2022. Register now!
https://link.webropolsurveys.com/S/3DDBBAFB7CE653B0
Digital poster exhibition
This year FINDOS Symposium digital poster session will be organized as “Read by title” presentations. All National FINDOS doctoral candidates and other researchers and research groups are invited to send their digital posters in PowerPoint presentation form that could be presented as “a read by title” presentation. The presentation will be viewable as a power point presentation on the spot on screen during the breaks. The presentations are running automatically on the screens but it is recommended that the researcher could be at the place on Thursday 12 May 2022 at 11.00-11.30 in Arje Schein lecture hall for questions and discussions with other researchers.
Instructions
The presentation should not include more than 3 slides.
The opening slide should display a straightforward title, name of the researcher and collaborators, affiliations and some attractive image. The objective, materials, and methods, results and conclusions should not exceed more than 250 words, and they should be presented in maximum of 2 slides.
Clinical patient cases can also be presented.
Submission of Posters (ppt) by 4 May 2022 to Coordinator Maiju Kannisto maiju.kannisto@utu.fi
We strongly encourage all study groups and researchers to present their studies in FINDOS Symposium!
If you want more information about the presentations, please contact Jaana Willberg jaana.willberg@utu.fi
Welcome!
May 6th at 13:00
virtual event
Spring 2022 prorgram
Nafis Rahman, MD, PhD, Adj. Prof:
Molecular mechanisms underlying selective progesterone receptor modulator mifepristone’s agonistic action on ovarian cancer progression
Elisa Närvä, PhD, Adj. Prof, University of Turku
Kinase-independent role of MASTL in breast cancer and in stemness
Chair: Matthieu Bourgery
Bimonthly IPP seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks.
Zoom link to join the seminar:
https://utu.zoom.us/s/68303022462
May 3rd at 14:00 – 15:00
Virtual event
Ludvig Sollid, Institute of Clinical Medicine and KG Jebsen Coeliac Disease Research Centre, University of Oslo and Department of Immunology, Oslo University Hospital: “
Triggers and drivers of autoimmunity
Registration latest May 2nd at: https://link.webropolsurveys.com/S/E8E36C4960A8B012
Zoom link and iCalendar invitation to join the online event will be sent to all registered participants one day before the event.
Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience. For further information contact Anne Lahdenperä ( ankahy@utu.fi ) or Riitta Lahesmaa ( rilahes@utu.fi ), University of Turku.
Ludvig M. Sollid (MD, PhD) is a Professor at the University of Oslo and a Senior Consultant at the Oslo University Hospital – Rikshospitalet. He is also the Director of the KG Jebsen Coeliac Disease Research Centre and UiO FOCIS Centre of Excellence. His research interests are focused around genetics and immunology of autoimmune diseases.
His group has made important contributions to the understanding of the molecular basis of coeliac disease, in particular the role of HLA genes, the existence of gluten reactive (HLA-DQ restricted) T cells in the coeliac intestinal lesion, the identification of immunotoxic gluten peptide sequences and the involvement of the transglutaminase 2 in the pathogenesis of the disease. His group is currently working on the characterization of the antigen receptors of T cells and B cells that recognize the coeliac disease relevant antigens gluten and transglutaminase 2.
Sollid is the recipient of several research awards including the Research Council of Norway’s Møbius Prize for Outstanding Research, the Warren Prize for Excellence in Celiac Disease Research, the Rank Prize in Nutrition, the UEG Research Prize and the Jahre Medical Prize (junior award 1998 and senior award (2015). He currently serves on the editorial boards of Mucosal Immunology, Scandinavian Journal of Immunology, Tissue Antigens, Genes and Immunity and Gastroenterology.
Selected publications
Ludvig M Sollid, Bana Jabri. Triggers and drivers of autoimmunity: lessons from coeliac disease. Nat Rev Immunol 13:294-302, 2013.
Ludvig M Sollid. Epstein-Barr virus as a driver of multiple sclerosis. Sci Immunol. 7:eabo7799, 2022.
Roberto Di Niro, Luka Mesin, Nai-Ying Zheng, Jorunn Stamnaes, Michael Morrissey, Jane-Hwei Lee, Min Huang, Rasmus Iversen, M Fleur du Pré, Shuo-Wang Qiao, Knut E A Lundin, Patrick C Wilson, Ludvig M Sollid.
High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions. Nat Med 18:441-5, 2012.
Asbjørn Christophersen, Eivind G Lund, Omri Snir, Elsa Solà, Chakravarthi Kanduri, Shiva Dahal-Koirala, Stephanie Zühlke, Øyvind Molberg, Paul J Utz, Mina Rohani-Pichavant, Julia F Simard, Cornelia L Dekker, Knut E A Lundin, Ludvig M Sollid, Mark M Davis. Distinct phenotype of CD4 + T cells driving celiac disease identified in multiple autoimmune conditions. Nat Med 25:734-737, 2019.
M Fleur du Pré, Jana Blazevski, Alisa E Dewan, Jorunn Stamnaes, Chakravarthi Kanduri, Geir Kjetil Sandve, Marie K Johannesen, Christian B Lindstad, Kathrin Hnida, Lars Fugger, Gerry Melino, Shuo-Wang Qiao, Ludvig M Sollid. B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2. J Exp Med 217:e20190860, 2020.
Alhopuro auditorium, Medisiina D, Kiinamyllynkatu 10, Turku
May 3rd at 14:00
hybrid event
Alhopuro hall / Zoom
New Cutting-Edge Methods in Cancer Research
14.00 Tapio Lönnberg “Single-cell and spatially resolved sequencing approaches to explore tissue composition”
14.20 Pia Rantakari “Spatial image analysis with Imagine mass cytometry”
14.40 Pekka Ruusuvuori “Quantitative analysis of multiplex stained tissue”
15.00 Coffee Break
15.15 Johanna Lilja “Multiplex Immunofluorescence Imaging to explore tissue spatial organization”
15.35 Emilia Peuhu “Spatial tissue engineering with 3D bioprinting”
15.55 Otto Kauko “Mass spectrometry-based proteomics in cancer research”
REGISTRATION
Only for those attending on-site at Alhopuro hall:
https://link.webropolsurveys.com/S/EA289CC2172B96F2
Join Zoom Meeting: https://utu.zoom.us/j/66586666315
Passcode: 010040
#April
April 29th at 09:00
Virtual event
Program
The universities in Turku, in close collaboration with Turku Science Park, have launched a joint Aboa Tech Talks webinar series focusing on emerging technologies and sustainable development. Aboa Tech Talks aims to highlight advanced and innovative technological research and education carried in the universities that can offer sustainable solutions to the complex global challenges of our time. The topic of this webinar is sustainable shipping.
Aboa Tech Talks – Sustainable Shipping is an online event and it is free of charge and open to anyone interested, including representatives from industry, government, the third sector, researchers and students. The event’s language is English and it is held in Teams. You will receive a link to the event after registration. Novia UAS, Campus Aboa Mare will moderate the event.
Registration and detailed program
Sari Repka, University of Turku
Pursuit of zero-emission shipping
Magnus Gustafsson, Åbo Akademi University
Business models for decarbonizing shipping
Jari M. Lahtinen, Turku University of Applied Sciences
Management of The Ship Environmental Load
Magnus Winberg, Novia University of Applied Sciences / Aboa Mare
Sustainable development in maritime education & training
Dani Lindberg, Viking Line Abp
Sustainable Shipping in the Baltic Sea and Viking Glory
Apri 27th at 11:15
Virtual event only
Adj. Prof Maria Lankinen, Institute of Public Health and Clinical Nutrition, UEF
Gene-diet interactions in polyunsaturated fatty acid metabolism and inflammation
Host: Kirsi Laitinen
April 22nd at 13:00
virtual event
Spring 2022 prorgram
Pieta Mattila, PhD, Adj. Prof, University of Turku
Dissecting early B cell activation with microscopic and proteomic tools
Hanna Heikelä, MSc (MP)
HSD17Bs in steroid and lipid metabolism and lipid disorders: The role of HSD17B12 and HSD17B13
Chair: Noora Houttu
Bimonthly IPP seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks.
Zoom link to join the seminar:
https://utu.zoom.us/s/68303022462
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
April 13th at 11:15
Hybrid event
Medisiina D, Säätiö / Zoom
Jukka Alinikula
Somatic hypermutation of antibody genes and beyond
Zoom details for virtual participants:
https://utu.zoom.us/j/7562392825
Program for all spring 2022 Infections and Immunity Seminars
Alhopuro auditorium, Medisiina D, Kiinamyllynkatu 10, Turku
April 5th at 15:00
hybrid event
Alhopuro hall / Zoom
TCRS Young PI Award 2021 Lectures
Hongbo Zhang
Solution for Health with Functional Materials
Guillaume Jacquemet
Studying cancer cell metastases in the era of Deep Learning for microscopy
Join Zoom Meeting: https://utu.zoom.us/j/66586666315
Passcode: 010040
April 5th at 14:00
Virtual event
Spring 2022 program
Bernard Malissen, Centre d’Immunologie de Marseille-Luminy, France
Quantitative interactomics of the TCR signal-transduction network and of its co-inhibitors
Flyer
Registration latest Apr 4 at: https://link.webropolsurveys.com/S/DABCBD92434374D1
Zoom link and iCalendar invitation to join the online event will be sent to all registered participants one day before the event.
Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience.
For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.
Bernard Malissen is the Founding-Director of the Center for Immunophenomics (Marseille, France; https://ciphe.marseille.inserm.fr/en/ ) and Director of the Team ‘Integrative Biology of T cells and Dendritic cells’ at Centre d’Immunologie de Marseille Luminy (http://www.ciml.univ-mrs.fr/science/lab-bernard-marie-malissen/home ). Bernard Malissen pioneered in the eighties the use of gene transfer approaches to dissect the function of Major Histocompatibility Complex (MHC) molecules. He also succeeded reconstructing a full T cell antigen receptor (TCR) complex and demonstrated that the present-day signaling subunits associated with antigen receptors stem from a common primordial building block. He provided the first evidence for chromosomal inversion during TCR gene rearrangements. His team was also the first to elucidate the atomic structure of an alloreactive TCR in complex with its peptide-MHC ligand, providing a molecular explanation for the basis of transplant rejection and contributing to unveil the structural basis of TCR binding-degeneracy. His recent interests extend to dendritic cells and macrophages, leading his team to disentangle their functional complexity in the skin. To make sense of the formidable complexity of the signal transduction networks involved in T cell activation, he recently combined “omic” approaches that measure large numbers of parameters and genetic screens. His recent work provided a systems level picture of the TCR signal transduction network and of its tuning by costimulatory and coinhibitory receptors. Such systems-level approaches highlighted the conservation and dissimilarities between human and mouse T cells.
Selected publications
Nicolas, P., J. Ollier, D. Mori, G. Voisinne, J. Celis-Gutierrez, C. Gregoire, J. Perroteau, R. Vivien, M. Camus, O. Burlet-Schiltz, A. Gonzalez de Peredo, B. Clemenceau, R. Roncagalli, H. Vie, and B. Malissen. 2022. Systems-level conservation of the proximal TCR signaling network of mice and humans. J Exp Med 219: e20211295
Voisinne, G., K. Kersse, K. Chaoui, L. Lu, J. Chaix, L. Zhang, M. Goncalves Menoita, L. Girard, Y. Ounoughene, H. Wang, O. Burlet-Schiltz, H. Luche, F. Fiore, M. Malissen, A. Gonzalez de Peredo, Y. Liang, R. Roncagalli, and B. Malissen. 2019. Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics. Nat Immunol 20:1530-1541.
Celis-Gutierrez, J., P. Blattmann, Y. Zhai, N. Jarmuzynski, K. Ruminski, C. Gregoire, Y. Ounoughene, F. Fiore, R. Aebersold, R. Roncagalli, M. Gstaiger, and B. Malissen. 2019. Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy. Cell Rep 27:3315-3330 e3317.
Mori, D., C. Gregoire, G. Voisinne, J. Celis-Gutierrez, R. Aussel, L. Girard, M. Camus, M. Marcellin, J. Argenty, O. Burlet-Schiltz, F. Fiore, A. Gonzalez de Peredo, M. Malissen, R. Roncagalli, and B. Malissen. 2021. The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation. J Exp Med 218: e20201011
April 1st at 13:00
virtual event
Spring 2022 prorgram
Riku Klén, Asst. Prof., PhD, University of Turku
Predictive models in cardiac research
Pia Rantakari, PhD, Adj. Prof, University of Turku
A new view of macrophages in endocrine tissues
Chair: Guillermo Martinez-Nieto
Bimonthly IPP seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks.
Zoom link to join the seminar:
https://utu.zoom.us/s/68303022462
#March
Aurum, Argentum auditorium, Henrikinkatu 2, Turku
March 31st at 13:30
on-site event in Aurum, Auditorium Argentum
Open doors at Aurum, Biomaterial research infra in Aurum and junior researcher networking
Hosts: Chunlin Xu (cxu@abo.fi) and Leena Hupa (leena.hups@abo.fi)
The aim is to promote interactive activities within Biomaterials and Medical Devices research programme. We hope that by arranging this networking event researchers, particularly junior ones (PhD students and postdocs), can meet and brainstorm cooperative ideas.
The proposed agenda
13:30 gathering and coffee
14:00 introduction (who, which research unit, research topics and interests), Auditorium Argentum
14:30 short introduction to Aurum and research activities in Aurum 14:30, lab tours
Please register latest 27.3. by sending email to cxu@abo.fi
Welcome!
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
March 30th at 11:30
Hybrid event
Medisiina D, Säätiö / Zoom
Adjunct professor Maria Lankinen, Institute of Public Health and Clinical Nutrition, UEF
Gene-diet interactions in polyunsaturated fatty acid metabolism and inflammation
host: Kirsi Laitinen
Zoom details for virtual participants:
https://utu.zoom.us/j/7562392825
Program for all spring 2022 Infections and Immunity Seminars
March 24th at 14:00
virtual event
In collaboration with the InFLAMES Flagship Meso Scale Discovery (MSD) invites you to introduction webinar on Multiplex immunoassay platform. The webinar will give an introduction to validated and flexible multiplex assays for biomarkers in several research fields such as inflammation, neuro, diabetes, cancer and so on. Since it is an open platform you may also use it for ADA, PK assays, ELISA conversion and more. At the moment MSD SARS- CoV2 panels, including both wild type and different variants are highly used world wide.
Register by email to receive a link to the webinar: Eva Ludvigsen, eludvigsen@mesoscale.com, +46 70 3790433
March 18th at 13:00
virtual event
Spring 2022 prorgram
Vappu Nieminen-Pihala, MSc (RK)
Transcription factors Ebf1 and Ebf2 in bone metabolism
Riikka Huhtaniemi, MSc (MP)
Androgen receptor related therapy resistance in prostate cancer: From disease model to mechanisms
Chair: Mehrad Mahmoudian
Bimonthly IPP seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks.
Zoom link to join the seminar:
https://utu.zoom.us/s/68303022462
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
CANCELLED
March 16th at 10:15
Hybrid event
Medisiina D, Säätiö / Zoom
Eeva-Liisa Eskelinen
Membrane dynamics during autophagosome formation and maturation
Zoom details for virtual participants:
https://utu.zoom.us/j/7562392825
Program for all spring 2022 Infections and Immunity Seminars
virtual event
Deepankar Chakroborty
Developing a high-throughput screen to identify activating mutations in tyrosine kinases
Eva-Maria Talvitie
A high number of targetable genomic alterations in lung adenocarcinoma in a Southwestern Finnish population
Cancer Research Seminar Series – organized by Turku Cancer Research Society and FICAN West
Zoom details to join the seminar
https://utu.zoom.us/j/66586666315
Meeting ID: 665 8666 6315
Passcode: 010040
March 4th at 13:00
virtual event
Spring 2022 prorgram
Adj. Prof. Renata Prunskaite-Hyyryläinen, University of Oulu
Novel testes gene function in spermatogenesis and 3D uterine morphology
Adj. Prof. Kaisa Ivaska-Papaioannou
Insights into bone marrow adiposity in metabolic disorders
Chair: Ella Koivuniemi
Bimonthly IPP seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks.
Zoom link to join the seminar:
https://utu.zoom.us/s/68303022462
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
March 2nd at 11:15
Hybrid event
Medisiina D, Säätiö / Zoom
Pieta Mattila
Dissecting early B cell activation with microscopic and proteomic tools
Zoom details for virtual participants:
https://utu.zoom.us/j/7562392825
Program for all spring 2022 Infections and Immunity Seminars
March 1st at 14:00
Virtual event
Spring 2022 program
Heikki Hyöty, Tampere University
Type 1 diabetes, enterovirus and prospects of vaccine development
Flyer
Registration latest Feb 28 at https://link.webropolsurveys.com/S/64C9EC43374D8B69
Zoom link and iCalendar invitation to join the online event will be sent to all registered participants one day before the event.
Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience.
For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.
Dr. Heikki Hyöty is Professor of Virology at Tampere University, Faculty of Medicine and Health Technology since 2013. Prof. Hyöty has received his PhD in virology in 1989. He has served as Professor of Biomedicine and Virology at University of Tampere prior to his current position. Prof. Hyöty leads a virology group that studies the role of viruses and other microbes in immune-mediated diseases including type 1 diabetes, asthma, allergy and celiac disease. The group has studied microbe-disease associations in prospective cohorts and translated innovations to develop new treatments and better diagnostics. One major initiative is the project developing an enterovirus vaccine that could prevent severe enterovirus diseases and type 1 diabetes. This project has generated a vaccine against Coxsackie B viruses which have been linked to type 1 diabetes. Professor Hyöty is coordinator of four EU funded projects, and has 422 original articles and altogether nine patents/patent applications.
Selected publications
Sioofy-Khojine AB, Lehtonen J, Nurminen N, Laitinen OH, Oikarinen S, Huhtala H, Pakkanen O, Ruokoranta T, Hankaniemi MM, Toppari J, Vähä-Mäkilä M, Ilonen J, Veijola R, Knip M, Hyöty H. Coxsackievirus B infections are associated with the initiation of insulin-driven autoimmunity that progress to type 1 diabetes. Diabetologia 6:1193-1202, 2018.
Hyöty H, Leon F, Knip M. Developing a vaccine for Type 1 diabetes by targeting coxsackievirus B. Expert Rev Vaccines. 17(12):1071-1083, 2018.
Vehik K, Lynch KF, Wong MC, Tian X, Ross MC, Gibbs RA, Ajami NJ, Petrosino JF, Rewers M, Toppari J, Ziegler AG, She JX, Lernmark A, Akolkar B, Hagopian WA, Schatz DA, Krischer JP, Hyöty H, Lloyd RE, and the TEDDY Study Group. Prospective virome analyses reveals prolonged enterovirus B shedding precedes islet autoimmunity in children at increased genetic risk for type 1 diabetes. Nat Med. 25(12):1865-1872, 2019.
Stone VM, Butrym M, Hankaniemi MM, Sioofy-Khojine A-B, Hytönen VP, Hyöty H, Flodström-Tullberg M. Coxsackievirus B vaccines prevent infection-accelerated diabetes in NOD mice and have no disease-inducing effect. Diabetes 70(12):2871-2878, 2021.
Oikarinen S, Krogvold L, Edwin B, Buanes T, Korsgren O, Laiho JE, Oikarinen M, Ludvigsson J, Skog O, Anagandula M, Frisk G, Hyöty H*, Dahl-Jørgensen K*. Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study. Diabetologia 64(11):2491-2501, 2021.
#February
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
February 18th at 13:00
on-site event
Arje Scheinin auditorium, Dentalia
Spring 2022 prorgram
Ilpo Huhtaniemi
Good and bad testosterone
Chair: Nafis Rahman
Bimonthly IPP seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks.
Skooppi 1&2, Medisiina D, Kiinamyllynkatu 10, Turku
February 17th at 11:15
Virtual event
Arno Hänninen
Microbiota and gut immune system in infancy and in autoimmune disease
Zoom details:
https://utu.zoom.us/j/7562392825
Program for all spring 2022 Infections and Immunity Seminars
February 17th at 09:30
Virtual event
Flyer
Program
The increasing use of renewable wind and solar energy will result in variations in the energy supply, depending on weather conditions and time of the day. Sustainable energy storage solutions will be needed to balance such variations. Join the webinar to learn more about the emerging technical solutions in academia and industry.
Speakers
Anne Nordström, TUAS, opening words
Henrik Saxén, ÅAU, A review of electrical energy storage
Pekka Peljo, UTU, Pathways towards sustainable stationary energy storage
Osmo Huhtala, TUAS, LVDC microgrids with renewable energy sources
Rainer Nurkkala, Elcon Solutions Oy, Battery system for positive energy district
More details about the event:
https://www.turkuamk.fi/fi/tapahtumat/1081/aboa-tech-talks-sustainable-energy-storage-solutions/
Register via Lyyti:
https://www.lyyti.fi/reg/Aboa_Tech_Talks_Sustainable_Energy_Storage_Solutions_4448
Welcome!
virtual event
Sara Zanivan, Cancer Research UK
Cancer associated fibroblasts: the architects of tumour stroma remodeling
Host: Elisa Närvä
Cancer Research Seminar Series – organized by Turku Cancer Research Society and FICAN West
Zoom details to join the seminar
https://utu.zoom.us/j/66586666315
Meeting ID: 665 8666 6315
Passcode: 010040
February 9th at 13:00
Virtual event
Article to be presented:
“Confronting false discoveries in single-cell differential expression”
https://www.nature.com/articles/s41467-021-25960-2
Please join the meeting in Zoom: https://utu.zoom.us/j/69319211252
Medical Bioinformatics Centre (MBC) welcomes everybody to the Bioinformatics Journal Club, where the aim is to get to know the latest development in the bioinformatics field and how bioinformatics solutions help advance biomedical research. Students have an opportunity to earn 1-5 ECTS credits by presenting and participating in the Bioinformatics Journal Club. Journal Club will be held once a month during Spring 2022.
February 4th at 13:00
Virtual event
Spring 2022 prorgram
Adj. Prof, Emilia Peuhu, University of Turku
Form follows function – Investigation of breast epithelial mechanics
Asst. Prof, Marie Lagerquist, University of Gothenburg, Sweden
Tissue-specific effects of membrane-initiated estrogen receptor alpha signaling
Chair and opening words: Matti Poutanen
Bimonthly IPP seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks.
Zoom link to join the seminar:
https://utu.zoom.us/s/68303022462
Skooppi 1&2, Medisiina D, Kiinamyllynkatu 10, Turku
February 2nd at 11:15
Hybrid event
Medisiina D, Skooppi 1+2 / Zoom
Teemu Smura, Department of Virology, University of Helsinki
How to sequence (Corona)viruses
host: Petri Susi
Zoom details for virtual participants:
https://utu.zoom.us/j/7562392825
Program for all spring 2022 Infections and Immunity Seminars
February 1st at 14:00
Virtual event
Spring 2022 program
Jenny Mjösberg, Karolinska Institutet
Tissue- and inflammation-specific imprinting of human innate lymphoid cells
Flyer
Registration latest Jan 31 at: https://link.webropolsurveys.com/S/60ED5C13513358D0
Zoom link and iCalendar invitation to join the online event will be sent to all registered participants one day before the event.
Immunology seminar series is jointly organised by the Finnish Society for Immunology, InFLAMES Flagship and Turku Bioscience.
For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.
Jenny Mjösberg is an associate professor at the Center for Infectious Medicine (CIM), Karolinska Institutet, Stockholm, Sweden. She earned her PhD in reproductive immunology at Linköping University, Sweden, in 2010. During her postdoc period in the lab of Hergen Spits at the AMC, Amsterdam, she contributed to the discovery of two novel subsets of human ILCs; ILC2 and ILC1. Since 2013, research in her own lab at CIM is focused on the importance of human ILCs in mucosal homeostasis and inflammation, mainly in the lung and gastrointestinal tract. Importantly, in 2016 Mjösberg provided the first transcriptional characterization of human ILCs on the single-cell level. These studies, along with continued transcriptional and epigenetic dissection of ILCs across several human organs have revealed previously unknown heterogeneity and a plethora of characteristics and regulatory mechanisms that control the function of specific ILC subsets. Her group ultimately aims at understanding the role of ILCs in asthma and gastrointestinal disease, including colorectal cancer and inflammatory bowel disease, for the development of novel therapeutic concepts.
Selected publications
- Mazzurana L, Czarnewski P, Jonsson V, Wigge L, Ringnér M, Williams TC, Ravindran A, Björklund ÅK, Säfholm J, Nilsson G, Dahlén SE, Orre AC, Al-Ameri M, Höög C, Hedin C, Szczegielniak S, Almer S, Mjösberg J. Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing. Cell Res. 2021 Jan 8. doi: 10.1038/s41422-020-00445-x.
- Rao A, Strauss O, Kokkinou E, Bruchard M, Tripathi KP, Schlums H, Carrasco A, Mazzurana L, Konya V, Villablanca EJ, Björkström NK, Lindforss U, Spits H, Mjösberg J. Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs. Nat Commun. 2020 Apr 27;11(1):2049.
- Maric J, Ravindran A, Mazzurana L, Björklund ÅK, van Acker A, Rao A, Kokkinou E, Ekoff M, Thomas D, Fauland A, Nilsson G, Wheelock CE, Dahlén E, Ferreirós N, Geisslinger G, Friberg D, Heinemann A, Konya V and Mjösberg J. Cytokine-induced endogenous production of PGD2 is essential for human ILC2 activation. J Allergy Clin Immunol (JACI). 2019 Jun; 143(6):2202-2214.
- Konya V, Czarnewski P, Rao A, Forkel M, Villablanca E, Almer S, Lindforss U, Friberg D, Höög C, Bergman P and Mjösberg J. Vitamin D downregulates the IL-23 receptor pathway in human mucosal ILC3. J Allergy Clin Immunol (JACI). 2018 Jan; 141(1):279-292.
- Björklund ÅK, Forkel M, Picelli S, Konya V, Theorell J, Friberg D, Sandberg R, Mjösberg J. The heterogeneity of human CD127+ innate lymphoid cells revealed by single-cell RNA-sequencing. Nat Immunol. 2016. 17(4):451-60.
#January
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
January 19th at 11:15
Hybrid event
Medisiina D, Säätiö / Zoom
Sirpa Jalkanen
InFLAMES Research Flagship – Solution is in Immunity
Zoom details for virtual participants:
https://utu.zoom.us/j/7562392825
Program for all spring 2022 Infections and Immunity Seminars
#December
Mauno Conferene Center, Presidentti auditorium, BioCity, Tykistökatu 6, Turku
16.12.2021 at 18–19
President auditorium, BioCity
Hybrid event
Flyer
Glögi and cookies will be served at 17.30
Prof. Dr. Lude Franke, Department of Genetics, University Medical Centre Groningen, Netherlands
Towards personalised, directed gene regulatory networks for better understanding common and rare diseases
Host: Riitta Lahesmaa (rilahes@utu.fi)
Register latest December 14th
https://link.webropolsurveys.com/S/7CBE4205F5B0DBC4
Zoom link and iCalendar invitation to join the online event will be sent to all registered participants one day before the event.
Please note: If you participate the seminar in President auditorium, be prepared to show a COVID-19 passport and ID.
Special Guest Seminar is jointly organised by InFLAMES Flagship, Lifespan research program and Turku Bioscience. For further information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahesmaa (rilahes@utu.fi), University of Turku.
Dr. Lude Franke is Full Professor of Functional Genomics in the Department of Genetics, University Medical Centre Groningen, where he guides his group on multi-omics data generation and analysis. His research group focuses in the development of computational methods to identify the downstream molecular effects of these disease-associated genetic variants.
The research line that he has set out over the last years involves the development and application of computational algorithms to functional genomics datasets. Lude Franke’s group is currently concentrating on integrating large-scale multi-omics datasets by conducting large-scale trans-QTL meta-analyses in >30,000 samples (Vosa et al, BioRxiv 2018) in conjunction with single-cell RNA-seq data (Van der Wijst et al, Nature Genetics 2018) with the principal aims to conduct eQTL meta-analysis and to reconstruct personalized regulatory networks that can be used to better understand disease-associated genetic variants. To do this optimally, they have initiated the single-cell eQTL consortium where >20 international research groups work towards a large-scale federated cell-type specific eQTL analysis in >3,000 samples and reconstruction of cell-type specific gene regulatory networks (Van der Wijst, eLife 2020).
Most recently, Lude Franke has initiated and leads the Lifelines COVID19 research project and accompanying CoronaBarometer website, a questionnaire-based study in 167,000 Lifelines biobank participants with the aim to contribute to the identification of risk factors for COVID19 susceptibility and severity, and to longitudinally study the impact of the COVID19 pandemic on the well-being of Dutch citizens.
Lude Franke has also received many prestigious grants such as VENI, VIDI, VICI, Oncode and ERC Starting Grants and he helds membership of the Young Academy (de Jonge Akademie, KNAW).
Relevant papers
- Large-scale cis-and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Urmo Võsa, Annique Claringbould, Harm-Jan Westra, Marc Jan Bonder, Patrick Deelen, …, Markus Scholz, Joseph Powell, Greg Gibson, Tõnu Esko, Lude Franke. Nat Genet. 2021 Sep;53:1300–1310
- Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs. van der Wijst MGP, Brugge H, de Vries DH, Deelen P, Swertz MA; LifeLines Cohort Study; BIOS Consortium, Franke L. Nat Genet. 2018 Apr;50(4):493-497.
- Disease variants alter transcription factor levels and methylation of their binding sites. BonderMJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van ‘t Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ; BIOS Consortium, Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, ‘t Hoen PA, Franke L, Heijmans BT. Nat Genet. 2017 Jan;49(1):131-138
- Identification of context-dependent expression quantitative trait loci in whole blood. Zhernakova DV, Deelen P, Vermaat M, van Iterson M, van Galen M, Arindrarto W, van ‘t Hof P, Mei H, van Dijk F, Westra HJ, Bonder MJ, van Rooij J, Verkerk M, Jhamai PM, Moed M, Kielbasa SM, Bot J, Nooren I, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, Zhernakova A, Li Y, Tigchelaar EF, de Klein N, Beekman M, Deelen J, van Heemst D, van den Berg LH, Hofman A, Uitterlinden AG, van Greevenbroek MM, Veldink JH, Boomsma DI, van Duijn CM, Wijmenga C, Slagboom PE, Swertz MA, Isaacs A, van Meurs JB, Jansen R, Heijmans BT, ‘t Hoen PA, Franke L. Nat Genet. 2017 Jan;49(1):139-145. doi: 10.1038/ng.3737
- Gene expression analysis identifies global gene dosage sensitivity in cancer. FehrmannRS, Karjalainen JM, Krajewska M, Westra HJ, Maloney D, Simeonov A, Pers TH, Hirschhorn JN, Jansen RC, Schultes EA, van Haagen HH, de Vries EG, te Meerman GJ, Wijmenga C, van Vugt MA, Franke L. Nat Genet. 2015 Feb;47(2):115-25.
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
December 15th at 16:00
Hybrid event
Medisiina D, Säätiö-Sali / Zoom
Kaisu Rantakokko-Jalava
Uuden I:n määritelmä
Asko Järvinen, HUS
Mikä on iso annos mikrobilääkettä?
Esa Rintala, TYKS
Muiden infektiotautien epidemiologia COVID-19 –pandemian aikana
Zoom-linkki:
https://utu.zoom.us/j/67597804008
Luentoja (8 h) anotaan hyväksyttäväksi täydennyskoulutukseksi erikoislääkäri- ja erikoishammaslääkärikoulutukseen kaikille erikoisaloille ja tohtorin tutkinnon jatkokoulutukseen.
Main Building, Säästöpankki lecture hall, University Hill, Turku
December 14th at 09:30
Hybrid event
Main Building, Säästöpankki lecture hall, and online
Flyer
Coffee and snack is served at 09:15 at the event venue.
Yagut Allahverdiyeva-Rinne, University of Turku
Introductory words
Eva-Mari Aro, University of Turku
Photosynthesis at the forefront of sustainability
Miikka Frantti, Solar Finland Group
Photovoltaic business in Finland, and R&D cooperation with higher education institutions
Kati Miettunen, University of Turku
Sustainable solar energy
Samuli Ranta, Turku University of Applied Sciences
Photovoltaic as part of the Nordic energy system
Jan-Henrik Smått, Åbo Akademi University
Research on emerging solar cells at Åbo Akademi University
The universities in Turku, in close collaboration with Turku Science Park, have launched a joint Aboa Tech Talks webinar series this autumn focusing on emerging technologies and sustainable development. Aboa Tech Talks aims to highlight advanced and innovative technological research and education carried in the universities that can offer sustainable solutions to the complex global challenges of our time.
The topic of the second Aboa Tech Talks is solar driven technologies and how researchers aim to address the major global sustainability challenges of our modern society. Solar powered technologies harness energy from sunlight, which is a main source of sustainable energy, and transform it into useable form in our daily lives. The goal of these technologies is to develop novel harvesting solutions for solar energy with higher conversion efficiencies. Aboa Tech Talks will stimulate a cooperation between the Universities, facilitate interaction with industry, and promote multidisciplinary education as an enabler of clean solar technology development in the Turku region.
Participants outside UTU, ÅAU, TUAS and Novia are invited to attend the event virtually.
The link to Flinga board to ask questions, and the link to join the virtual event will be sent to all registered participants one day before the event.
Register latest December 12th
https://link.webropolsurveys.com/S/F5C6AE3A9A30DF2B
.
December 10th at 13:00
Virtual event
Autumn 2021 program
Adj. Prof. Petra Sipilä
Runx transcription factors are necessary for maintenance of propler differentiation of epididymal epithelial cells
Sarah El Kharraz, Univeristy of Leuven, Belgium
Androgen receptor dimerization: frim crystals to nouse models
Bimonthly IPP seminar series covers the diversity of biomedical/medical research performed in Integrative Physiology and Pharmacology research unit plus interesting talks by visitors from national and international research collaboration networks.
Details to join the Zoom are available on the same week Monday in BioCity Announcements
#October
Mauno Conferene Center, Presidentti auditorium, BioCity, Tykistökatu 6, Turku
October 28th at 09:00
on-site event
BioCity Presidentti auditorium
Alexander Mildner, Max-Delbrück Center for Molecular Medicine, Berlin, Germany
title tba
You are warmly welcome to the seminar of Alexander Mildner from Max-Delbrück Center for Molecular Medicine, Berlin, Germany. Alexander Mildner has applied for an InFLAMES Associate Professorship position and is a top candidate for the position. He will visit Turku from 27 to 29 October. Coffee/tea and sandwich is served before the start of the seminar.
If you would like to meet and talk with him in person, please email kaisa.hakkila@utu.fi.
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
October 12th at 15:15
Hybrid event
Medisiina D lecture hall Lauren 1 / Zoom
Prof. Simon L. Goodman, Science and Technology Program Manager, the Antibody Society, Germany
Integrins as drug targets
Professor Goodman will be holding his lecture about the topic of integrins as drug targets on-site in the Medisiina D lecture hall Lauren 1. If you wish to come on-site please register latest Sunday October 10th
https://link.webropol.com/s/VP-Simon-Goodman
You can also follow the talk online via Zoom, where no registration is required:
https://utu.zoom.us/j/61710469294
Welcome everyone!
Simon L. Goodman is Science and Technology Program Manager for the Antibody Society. He gained his D.Phil in membrane biochemistry from the University of Sussex. His start-up biotechnology company works on antibody validation. He spent many years at Merck inventing and developing peptide and antibody therapeutics targeting cell adhesion through phase 3 clinical trials in oncology. Prior to Merck, he did post-doctoral work at Max-Planck Society on cellular receptors for laminin, with Klaus von der Mark at Martinsried, Munich and Erlangen, and phenotypic antibody screens with Walter Birchmeier at MPI Tübingen. His work includes the first high resolution X-ray structures of integrins, in collaboration with Dr. Amin Arnaout (Harvard Medical School). His career in academia and industry has resulted in over 100 peer-reviewed publications, reviews and in many patents.
“InFLAMES: Visiting professor lecture by Simon Goodman”October 12th at 15:15
Hybrid event
Medisiina D lecture hall Lauren 1 / Zoom
Prof. Simon L. Goodman, Science and Technology Program Manager, the Antibody Society, Germany
Integrins as drug targets
Professor Goodman will be holding his lecture about the topic of integrins as drug targets on-site in the Medisiina D lecture hall Lauren 1. If you wish to come on-site please register latest Sunday October 10th
https://link.webropol.com/s/VP-Simon-Goodman
You can also follow the talk online via Zoom, where no registration is required:
https://utu.zoom.us/j/61710469294
Welcome everyone!
Simon L. Goodman is Science and Technology Program Manager for the Antibody Society. He gained his D.Phil in membrane biochemistry from the University of Sussex. His start-up biotechnology company works on antibody validation. He spent many years at Merck inventing and developing peptide and antibody therapeutics targeting cell adhesion through phase 3 clinical trials in oncology. Prior to Merck, he did post-doctoral work at Max-Planck Society on cellular receptors for laminin, with Klaus von der Mark at Martinsried, Munich and Erlangen, and phenotypic antibody screens with Walter Birchmeier at MPI Tübingen. His work includes the first high resolution X-ray structures of integrins, in collaboration with Dr. Amin Arnaout (Harvard Medical School). His career in academia and industry has resulted in over 100 peer-reviewed publications, reviews and in many patents.
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
October 11th at 11:15
Hybrid event
Medisiina D lecture hall Lauren 1 / Zoom
Prof. Simon L. Goodman, Science and Technology Program Manager, the Antibody Society, Germany
Drug discovery and how things are done in pharma
Professor Goodman will be holding his introductory lecture on-site in the Medisiina D Lecture Hall Lauren 1. If you wish to come on-site please register latest Sunday October 10th
https://link.webropol.com/s/VP-Simon-Goodman
You can also follow the talk online via Zoom, where no registration is required:
https://utu.zoom.us/j/66366373791
Welcome everyone!
Simon L. Goodman is Science and Technology Program Manager for the Antibody Society. He gained his D.Phil in membrane biochemistry from the University of Sussex. His start-up biotechnology company works on antibody validation. He spent many years at Merck inventing and developing peptide and antibody therapeutics targeting cell adhesion through phase 3 clinical trials in oncology. Prior to Merck, he did post-doctoral work at Max-Planck Society on cellular receptors for laminin, with Klaus von der Mark at Martinsried, Munich and Erlangen, and phenotypic antibody screens with Walter Birchmeier at MPI Tübingen. His work includes the first high resolution X-ray structures of integrins, in collaboration with Dr. Amin Arnaout (Harvard Medical School). His career in academia and industry has resulted in over 100 peer-reviewed publications, reviews and in many patents.
#May
Special seminar, program will be announced later
Zoom details
https://utu.zoom.us/j/67279196618
Meeting ID: 672 7919 6618
Passcode: 878028
May 19th at 13:00
Virtual event
We will be hosting Prof. Vincenzo Cerullo, Group leader of ImmunoViroTherapy Lab, University of Helsinki, for the talk. The duration of the talk is 30 mins followed by 15 mins of discussion and interaction with the speaker.
Title of the talk: “Dressing up viruses to fool cancer”
You can register here: http://bit.ly/cerullo. This link is active until 18th May 23:59.
Brief Bio about the speaker: Prof. Vincenzo Cerullo, Vince is professor of Biological Drug Development, Faculty of Pharmacy, Head of Drug Research Program, HiLIFE fellow, Translational Immunology Programme, University of Helsinki. Vince got his PhD at Centre for genetic Engineering (CENIGE) at University of Naples, Federico II in 2004, then he moved to Houston Texas (USA) for a postdoc at Baylor College of Medicine. In 2009 he moved to University of Helsinki where he worked as senior researcher until 2012 when he was awarded the tenure-track professorship and started the ImmunoViroTherapy Lab. In these years IVTLab has raised more than 7 million Euros for research, including the prestigious ERC Consolidator Grant, ERC-PoC, HiLIFE fellow and Jane and Aatos Erkko Foundation grant. The group has produced tens of scientific papers and patents and has co-founded a multimillion spin-off company together with the University of Helsinki (VALO therapeutics). Vince has been awarded the Outstading Young Investigator award in 2014 by the European Society of Gene and cell Therapy and the Excellence in Research award by the American Society of Gene and Cell Therapy in 2015; he has been recently ranked number one globally, third in Europe and number one in the nordic in his own experitiese (oncolytic virotherapy) by expertscape.
One of Vince’s passion is science dissemination, this is why has been involved from the beginning in organizing the Science track in Slush, he has pitched himself on the Slush stage in 2015, 2016 and on the Slush Y Science stage in 2017 (www.slush.org). Among other things, he has also presented a TEDx talk on the importance of creativity in science (https://youtu.be/1btbElPnREI)
More details about research can be found here: https://www2.helsinki.fi/en/researchgroups/immunovirotherapy-lab/research
“Postdoc and PhD students seminar: Cerullo”May 19th at 13:00
Virtual event
We will be hosting Prof. Vincenzo Cerullo, Group leader of ImmunoViroTherapy Lab, University of Helsinki, for the talk. The duration of the talk is 30 mins followed by 15 mins of discussion and interaction with the speaker.
Title of the talk: “Dressing up viruses to fool cancer”
You can register here: http://bit.ly/cerullo. This link is active until 18th May 23:59.
Brief Bio about the speaker: Prof. Vincenzo Cerullo, Vince is professor of Biological Drug Development, Faculty of Pharmacy, Head of Drug Research Program, HiLIFE fellow, Translational Immunology Programme, University of Helsinki. Vince got his PhD at Centre for genetic Engineering (CENIGE) at University of Naples, Federico II in 2004, then he moved to Houston Texas (USA) for a postdoc at Baylor College of Medicine. In 2009 he moved to University of Helsinki where he worked as senior researcher until 2012 when he was awarded the tenure-track professorship and started the ImmunoViroTherapy Lab. In these years IVTLab has raised more than 7 million Euros for research, including the prestigious ERC Consolidator Grant, ERC-PoC, HiLIFE fellow and Jane and Aatos Erkko Foundation grant. The group has produced tens of scientific papers and patents and has co-founded a multimillion spin-off company together with the University of Helsinki (VALO therapeutics). Vince has been awarded the Outstading Young Investigator award in 2014 by the European Society of Gene and cell Therapy and the Excellence in Research award by the American Society of Gene and Cell Therapy in 2015; he has been recently ranked number one globally, third in Europe and number one in the nordic in his own experitiese (oncolytic virotherapy) by expertscape.
One of Vince’s passion is science dissemination, this is why has been involved from the beginning in organizing the Science track in Slush, he has pitched himself on the Slush stage in 2015, 2016 and on the Slush Y Science stage in 2017 (www.slush.org). Among other things, he has also presented a TEDx talk on the importance of creativity in science (https://youtu.be/1btbElPnREI)
More details about research can be found here: https://www2.helsinki.fi/en/researchgroups/immunovirotherapy-lab/research
#April
Janne Koskinen, ArcDia International Oy
Company perspective on R&D in clinical microbiology and virology
Organized in Zoom
https://utu.zoom.us/j/7562392825
2 ECTS
KAB24007 (UTU)
TK00BS28-3003 (ÅAU)
course description
detailed program
Registration latest April 13th via Nettiopsu (UTU) or Peppi (ÅAU)
If you are from other organization but would ilke to register, please contact the responsible teachers.
The course deals with basic concepts of sustainability, bioeconomy and circular economy. It gives an overview of current and potential bioeconomy in Finland, starting from biomass resources and advanced conversion technologies to national and EU strategies. Lectures are given by top experts from different fields in industry and academia and the course includes a virtual excursion to the Smart Chemistry Park, which is South Western Finland’s technology innovation park largely devoted to bioeconomy and cleantech.
Academic lecturers
Eva-Mari Aro, University of Turku
Markku Kulmala, Univesity of Helsinki
Henrik Grénman, Åbo Akademi University
Yagut Allahverdiyeva, University of Turku
Chunlin Xu, Åbo Akademi University
Pauli Kallio, University of Turku
Tekla Tammelin, FinnCERES Flagship
Mikko Pohjola, University of UTU
Industry lecturers
Maija Pohjakallio, Sulapac Ltd.
Lari Vähäsalo, CH Bioforce
Antoine Mialon, MetGen
Aino-Maija Lakaniemi, Neste Oy
Blanka Toukoniitty, Neste Oy
Elina Peltomaa, Algonomy
Linda Fröberg-Niemi, Smart Chemistry Park
The students are expected to keep a learning diary throughout the course and at the end of the course each student is assigned one of the topics to plunge into and to write a final report. The in-depth essay should describe the Finnish as well as global current situation, reflect on the future and include literature search.
The course lasts three full days and requires full attendance but in case of colliding events students need to be in contact with the responsible teachers in advance. More detailed program is available in SmartBio web pages www.smartbio.fi as well as in Moodle. The course is intended for advanced Master students as well as for PhD students.
Responsible teachers
Prof. Yagut Allahverdiyeva (allahve@utu.fi)
Prof. Henrik Grénman (henrik.grenman@abo.fi)
2 ECTS
KAB24007 (UTU)
TK00BS28-3003 (ÅAU)
course description
detailed program
Registration latest April 13th via Nettiopsu (UTU) or Peppi (ÅAU)
If you are from other organization but would ilke to register, please contact the responsible teachers.
The course deals with basic concepts of sustainability, bioeconomy and circular economy. It gives an overview of current and potential bioeconomy in Finland, starting from biomass resources and advanced conversion technologies to national and EU strategies. Lectures are given by top experts from different fields in industry and academia and the course includes a virtual excursion to the Smart Chemistry Park, which is South Western Finland’s technology innovation park largely devoted to bioeconomy and cleantech.
Academic lecturers
Eva-Mari Aro, University of Turku
Markku Kulmala, Univesity of Helsinki
Henrik Grénman, Åbo Akademi University
Yagut Allahverdiyeva, University of Turku
Chunlin Xu, Åbo Akademi University
Pauli Kallio, University of Turku
Tekla Tammelin, FinnCERES Flagship
Mikko Pohjola, University of UTU
Industry lecturers
Maija Pohjakallio, Sulapac Ltd.
Lari Vähäsalo, CH Bioforce
Antoine Mialon, MetGen
Aino-Maija Lakaniemi, Neste Oy
Blanka Toukoniitty, Neste Oy
Elina Peltomaa, Algonomy
Linda Fröberg-Niemi, Smart Chemistry Park
The students are expected to keep a learning diary throughout the course and at the end of the course each student is assigned one of the topics to plunge into and to write a final report. The in-depth essay should describe the Finnish as well as global current situation, reflect on the future and include literature search.
The course lasts three full days and requires full attendance but in case of colliding events students need to be in contact with the responsible teachers in advance. More detailed program is available in SmartBio web pages www.smartbio.fi as well as in Moodle. The course is intended for advanced Master students as well as for PhD students.
Responsible teachers
Prof. Yagut Allahverdiyeva (allahve@utu.fi)
Prof. Henrik Grénman (henrik.grenman@abo.fi)
Alesia Levanova, University of Helsinki
Purification and analysis of small RNA molecules using asymmetrical flow field-flow fractionation (AF4)
Organized in Zoom
https://utu.zoom.us/j/7562392825
Karolina Louvanto, Methylation markers in cervical cancer screening
Akira Takeda, Stromal and immune cell interactions in health and disease
Zoom details
https://utu.zoom.us/j/67279196618
Meeting ID: 672 7919 6618
Passcode: 878028
#March
Tom Wiklund, Åbo Akademi University
Bacteriophages as biocontrol agents for cold water disease in farmed rainbow trout
Organized in Zoom
https://utu.zoom.us/j/7562392825
#November
Turku Cancer Research Society and FICAN West welcomes you to
Breast cancer research seminar
Online meeting (Zoom) 24.11.2020 at 14:00–16:15
Register by 15:00 23.11.2020 via https://link.webropolsurveys.com/S/B4881A726F375B73.
All those registered will receive a Zoom link once the registration is closed.
Please note that any audio or video recording of the seminar is strictly forbidden.
Programme
14.00 – 14.10 Opening
14.10 – 14.40 Marie Kveiborg, University of Copenhagen, The multifaceted role of ADAM proteases in breast cancer
14.40 – 15.10 Robert Clarke, University of Manchester, Signalling pathways regulating endocrine resistance and metastasis in breast cancer
Break
15.15 – 15.45 Heli Nevanlinna, University of Helsinki, Genetic susceptibility to breast and ovarian cancer
15.45 – 16.00 PhD thesis winner
16.00 – 16.15 Discussion and closing
#October
Turku Cancer Research Society and FICAN West welcome you to join a seminar afternoon “State-of-the-art methodologies in cancer research”. It will be an online meeting via Zoom:
https://utu.zoom.us/j/61464679658
ID: 614 6467 9658
Passcode: 365521
Programme
Session I:
13.00-13.25 Riikka Lund “Supporting high-level research with state-of-the-art tools for genomics”
13.25-13.50 Hongbo Zhang “Advanced Materials and Nanotechnology on Cancer Treatment” (changed)
13.50-14.15 Mari Suominen “Learning curve for using CD34 engrafted humanized mice”
14.15-14.40 Tove Grönroos “New applications in animal PET/CT imaging”
Break
Session II:
15.00-15.25 Christoffer Löf “The CRISPR toolkit in cancer research” (changed)
15.25-15.50 Pekka Ruusuvuori “Artificial intelligence for cancer diagnostics and grading” (changed)
15.50-16.15 Sofia Khan “Where lies the power of genome-wide association studies (GWAS)”
16.15-16.30 Discussion and closing
#June
Turku Doctoral Programme in Molecular Medicine (TuDMM) and the Finnish Euro-BioImaging Node is happy to announce a course “Basic Concepts of Bioimage Analysis” taking place in Turku BioCity between 12th-14th of June. The course will start at 12:00 on the 12th of June and complete at 17:00 on the 14th of June.
The course is aimed at graduate students, post-doctoral researchers, and everyone else who has background in imaging and microscopy and wish to gain additional insights into image analysis.
The 3-day course aims to cover the basics of image analysis and ethics involved in image analysis, fundamental concepts including convolution, segmentation, and many others with a hands-on practical component using ImageJ image analysis software working on participants’ own image analysis problems.
The maximum number of participants is 25 with participants selected based on their imaging background and suitability for the course.
More information here
Please register here: https://link.webropolsurveys.com/S/725C6B9DC91D0404
We are looking forward to your participation in this course.
“Basic Concepts of Bioimage Analysis –course”Turku Doctoral Programme in Molecular Medicine (TuDMM) and the Finnish Euro-BioImaging Node is happy to announce a course “Basic Concepts of Bioimage Analysis” taking place in Turku BioCity between 12th-14th of June. The course will start at 12:00 on the 12th of June and complete at 17:00 on the 14th of June.
The course is aimed at graduate students, post-doctoral researchers, and everyone else who has background in imaging and microscopy and wish to gain additional insights into image analysis.
The 3-day course aims to cover the basics of image analysis and ethics involved in image analysis, fundamental concepts including convolution, segmentation, and many others with a hands-on practical component using ImageJ image analysis software working on participants’ own image analysis problems.
The maximum number of participants is 25 with participants selected based on their imaging background and suitability for the course.
More information here
Please register here: https://link.webropolsurveys.com/S/725C6B9DC91D0404
We are looking forward to your participation in this course.
#May
Kurssal, Biocity 2nd floor, room no. 2097, 2098, Tykistökatu 6, Turku
Kati Kemppainen (Sahlgren lab): Introduction to the Cell Fate Lab
Maria Georgiadou (Orion Pharma): Making the transition – how to become a scientist in the industry
“Turku Bioscience postdoc seminar”Kati Kemppainen (Sahlgren lab): Introduction to the Cell Fate Lab
Maria Georgiadou (Orion Pharma): Making the transition – how to become a scientist in the industry
Medisiina D, Lauren 2 lecture hall, Kiinamyllynkatu 10, Turku
Spring Seminar Event – Prostate Cancer:
13-13.05 Maria Sundvall – Opening and introduction
13.05-13.25 Peter Boström “Treatment of localized prostate cancer”
13.25-13.45 Heikki Minn “Molecular imaging in prostate cancer”
13.45-14.30 Steven Bova “Evolution of lethal prostate cancer at primary and metastatic sites: Can we identify what is important?”
14.30-15.00 Coffee break & Sponsors talk
15.00-15.20 Laura Elo ”How machine learning can improve treatment of prostate cancer”
15.20-15.40 Riikka Oksala “Androgen signaling axis as drug target in castration-resistant prostate cancer”
15.40-16.00 Kirsi Ketola “Cellular plasticity in lethal neuroendocrine prostate cancer”
16.00-16.30 Presentations by winners of grants
16.30 Sparkling wine and snacks
Register by email no later than 3.5.2019: contact-tcrs@lists.utu.fi
Printable programme here
“Cancer seminar: Spring seminar – Prostate cancer”Spring Seminar Event – Prostate Cancer:
13-13.05 Maria Sundvall – Opening and introduction
13.05-13.25 Peter Boström “Treatment of localized prostate cancer”
13.25-13.45 Heikki Minn “Molecular imaging in prostate cancer”
13.45-14.30 Steven Bova “Evolution of lethal prostate cancer at primary and metastatic sites: Can we identify what is important?”
14.30-15.00 Coffee break & Sponsors talk
15.00-15.20 Laura Elo ”How machine learning can improve treatment of prostate cancer”
15.20-15.40 Riikka Oksala “Androgen signaling axis as drug target in castration-resistant prostate cancer”
15.40-16.00 Kirsi Ketola “Cellular plasticity in lethal neuroendocrine prostate cancer”
16.00-16.30 Presentations by winners of grants
16.30 Sparkling wine and snacks
Register by email no later than 3.5.2019: contact-tcrs@lists.utu.fi
Printable programme here
#April
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
Hussein Al-Akhrass SorLA – a novel oncogenic regulator of HER2-amplified breast cancer
Minna Piipponen Long non-coding RNAs in cutaneous squamous cell carcinoma
“Cancer seminar: Al-Akhrass / Piipponen”
Hussein Al-Akhrass SorLA – a novel oncogenic regulator of HER2-amplified breast cancer
Minna Piipponen Long non-coding RNAs in cutaneous squamous cell carcinoma
#March
Medisiina D, Lauren 2 lecture hall, Kiinamyllynkatu 10, Turku
Maija Hollmen Converting cold tumors hot -A macrophage targeted approach
Sami Ventelä New tools to diagnose and treat head and neck squamous cell carcinoma (HNSCC)
“Cancer seminar: Hollmen / Ventelä”
Maija Hollmen Converting cold tumors hot -A macrophage targeted approach
Sami Ventelä New tools to diagnose and treat head and neck squamous cell carcinoma (HNSCC)
#January
Medisiina D, Lauren 2 lecture hall, Kiinamyllynkatu 10, Turku
Valeriy Paramonov Profiling Notch signalling in digestive endocrine cancers
Maria Gardberg Exploring novel fusion genes in glioblastoma
“Cancer seminar: Paramonov / Gardberg”
Valeriy Paramonov Profiling Notch signalling in digestive endocrine cancers
Maria Gardberg Exploring novel fusion genes in glioblastoma
Mauno Conferene Center, Presidentti auditorium, BioCity, Tykistökatu 6, Turku
DRUG DEVELOPMENT AND DIAGNOSTICS MINI-SYMPOSIUM
TRANSLATING MOLECULES TO TREATMENTS II
9.00-9.10 Opening words by Professor Lea Sistonen
9.10-10.00 Thomas Kirkegaard Jensen Orphazyme – From Biology to Bedside
Thomas Kirkegaard Jensen is a PhD and Chief Scientific Officer of Orphazyme ApS in Denmark. Orphazyme develops new therapies for patients suffering from protein-misfolding diseases with no or limited treatment options available. Orphazyme was founded on the initial discovery made by Thomas during his doctoral studies in the laboratory of Professor Marja Jäättelä at the Danish Cancer Society, in which they found that the molecular chaperone, heat shock protein 70, reverts the pathology associated with lysosomal storage diseases. Based on this finding the company develops of new treatments for lysosomal storage diseases.
10.00-10.20 Coffee break
10.20-11.10 Rajwinder Lehal From Cell to Cellestia – Transition of a PhD Project Into a Drug Development Company
Rajwinder Lehal is a PhD and co-founder of Cellestia Biotech AG in Switzerland. The aim of Cellestia Biotech is to develop innovative therapeutics for cancer treatment. At Cellestia Biotech, he is Chief Scientific Officer and serves on the Board of Directors. Cellestia Biotech has developed a targeted therapy designed to treat cancers resulting from a mutation of the Notch gene. Molecule CB-103, discovered by Rajwinder Lehal during his doctoral studies in Professor Freddy Radtke’s laboratory at EPFL, cuts off Notch signals leading to cell death of cancer cells.
11.10-12.00 Mads Daugaard Leveraging Placental Malaria Tropism for Cancer Therapeutic and Diagnostic Applications
Mads Daugaard is an Assistant Professor and group leader at Vancouver Prostate Centre at University of British Columbia and the Co-founder and Chairman of the Board of Directors of three biotech companies; VAR2 Pharmaceuticals, OncoMal and VarCT Diagnostics in Canada. Mads is a molecular biologist specialized in tumour-associated stress signaling pathways and tumour targeting systems. His research focuses on alternative polyadenylation of mRNAs, chromatin context-dependent DNA repair, development of resistance to chemotherapy, and immune evasion mechanisms in cancer. Another aspect of Mads’ research relates to discovery and development of novel tumour targeting systems based on parasite-derived recombinant proteins relevant for therapeutic and diagnostic applications in cancer.
12.30-14.00 Round table lunch with speakers
Round table discussions including lunch for students and postdocs in groups of 10 students/postdocs per speaker. The 30 first to register will be admitted.
Register before Friday January 11th at https://survey.abo.fi/lomakkeet/10837/lomake.html
For more information, contact Annika Meinander, e-mail: annika.meinander@abo.fi
“TRANSLATING MOLECULES TO TREATMENTS II”
DRUG DEVELOPMENT AND DIAGNOSTICS MINI-SYMPOSIUM
TRANSLATING MOLECULES TO TREATMENTS II
9.00-9.10 Opening words by Professor Lea Sistonen
9.10-10.00 Thomas Kirkegaard Jensen Orphazyme – From Biology to Bedside
Thomas Kirkegaard Jensen is a PhD and Chief Scientific Officer of Orphazyme ApS in Denmark. Orphazyme develops new therapies for patients suffering from protein-misfolding diseases with no or limited treatment options available. Orphazyme was founded on the initial discovery made by Thomas during his doctoral studies in the laboratory of Professor Marja Jäättelä at the Danish Cancer Society, in which they found that the molecular chaperone, heat shock protein 70, reverts the pathology associated with lysosomal storage diseases. Based on this finding the company develops of new treatments for lysosomal storage diseases.
10.00-10.20 Coffee break
10.20-11.10 Rajwinder Lehal From Cell to Cellestia – Transition of a PhD Project Into a Drug Development Company
Rajwinder Lehal is a PhD and co-founder of Cellestia Biotech AG in Switzerland. The aim of Cellestia Biotech is to develop innovative therapeutics for cancer treatment. At Cellestia Biotech, he is Chief Scientific Officer and serves on the Board of Directors. Cellestia Biotech has developed a targeted therapy designed to treat cancers resulting from a mutation of the Notch gene. Molecule CB-103, discovered by Rajwinder Lehal during his doctoral studies in Professor Freddy Radtke’s laboratory at EPFL, cuts off Notch signals leading to cell death of cancer cells.
11.10-12.00 Mads Daugaard Leveraging Placental Malaria Tropism for Cancer Therapeutic and Diagnostic Applications
Mads Daugaard is an Assistant Professor and group leader at Vancouver Prostate Centre at University of British Columbia and the Co-founder and Chairman of the Board of Directors of three biotech companies; VAR2 Pharmaceuticals, OncoMal and VarCT Diagnostics in Canada. Mads is a molecular biologist specialized in tumour-associated stress signaling pathways and tumour targeting systems. His research focuses on alternative polyadenylation of mRNAs, chromatin context-dependent DNA repair, development of resistance to chemotherapy, and immune evasion mechanisms in cancer. Another aspect of Mads’ research relates to discovery and development of novel tumour targeting systems based on parasite-derived recombinant proteins relevant for therapeutic and diagnostic applications in cancer.
12.30-14.00 Round table lunch with speakers
Round table discussions including lunch for students and postdocs in groups of 10 students/postdocs per speaker. The 30 first to register will be admitted.
Register before Friday January 11th at https://survey.abo.fi/lomakkeet/10837/lomake.html
For more information, contact Annika Meinander, e-mail: annika.meinander@abo.fi
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
Professor James M Musser, Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas
The many secret lives of group A streptococcus, a human flesh-eating pathogen
“The many secret lives of group A streptococcus, a human flesh-eating pathogen”Professor James M Musser, Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas
The many secret lives of group A streptococcus, a human flesh-eating pathogen
Mauno Conferene Center, Presidentti auditorium, BioCity, Tykistökatu 6, Turku
DRUG DEVELOPMENT AND DIAGNOSTICS MINI-SYMPOSIUM
TRANSLATING MOLECULES TO TREATMENTS I
13.00-13.10 Opening words by Associate Professor Diana Toivola
13.10-14.00 M. Bishr Omary Molecular Pathogenesis of Porphyria and Therapeutic Approaches Using Zebrafish Models
M. Bishr Omary is Professor of Molecular & Integrative Physiology, the H Marvin Pollard Professor of Gastroenterology, Professor of Internal Medicine, and Special Advisor on Research to the Dean at University of Michigan in Ann Arbor, USA. He is also guest professor in Drug Development and Diagnostics at Åbo Akademi University in Turku. Bishr is a world leader in the area of intermediate filamentsand their associated diseases, with special focus on the regulation and function of keratins and lamins in digestive organs. Another active area of research in his laboratory involves studying the mechanism of porphyrin mediated cell damage in the context of the genetic porphyria disorders. He currently utilizes high throughput drug screening approaches to identify compounds with potential therapeutic benefits for intermediate filament associated diseases and for porphyrias.
https://medicine.umich.edu/dept/molecular-integrative-physiology/bishr-omary-md-phd
14:00-14.50 Caroline Heckman Personalizing Patient Care to Overcome Drug Resistance in Hematological Malignancies
Caroline Heckman is a Group leader and Principal Investigator at the Institute for Molecular Medicine Finland FIMM, Helsinki Institute of Life Sciences, University of Helsinki in Finland. Caroline’s research is focused on understanding the mechanisms driving disease progression and drug resistance in hematological malignancies. She also applies technologies for better translation of basic research results towards clinical implementation.
https://www.fimm.fi/en/research/groups/heckman
14.50-15.10 Coffee break
15.10-16.00 “The ABCs of a postdoc in the US” with M. Bishr Omary
This interactive session is open to all interested and will cover tips and advice on doing a postdoc in general and especially related to being a postdoc in US.
Register before Friday January 11th at https://survey.abo.fi/lomakkeet/10837/lomake.html
For more information, contact Diana Toivola, e-mail: diana.toivola@abo.fi
“TRANSLATING MOLECULES TO TREATMENTS I”
DRUG DEVELOPMENT AND DIAGNOSTICS MINI-SYMPOSIUM
TRANSLATING MOLECULES TO TREATMENTS I
13.00-13.10 Opening words by Associate Professor Diana Toivola
13.10-14.00 M. Bishr Omary Molecular Pathogenesis of Porphyria and Therapeutic Approaches Using Zebrafish Models
M. Bishr Omary is Professor of Molecular & Integrative Physiology, the H Marvin Pollard Professor of Gastroenterology, Professor of Internal Medicine, and Special Advisor on Research to the Dean at University of Michigan in Ann Arbor, USA. He is also guest professor in Drug Development and Diagnostics at Åbo Akademi University in Turku. Bishr is a world leader in the area of intermediate filamentsand their associated diseases, with special focus on the regulation and function of keratins and lamins in digestive organs. Another active area of research in his laboratory involves studying the mechanism of porphyrin mediated cell damage in the context of the genetic porphyria disorders. He currently utilizes high throughput drug screening approaches to identify compounds with potential therapeutic benefits for intermediate filament associated diseases and for porphyrias.
https://medicine.umich.edu/dept/molecular-integrative-physiology/bishr-omary-md-phd
14:00-14.50 Caroline Heckman Personalizing Patient Care to Overcome Drug Resistance in Hematological Malignancies
Caroline Heckman is a Group leader and Principal Investigator at the Institute for Molecular Medicine Finland FIMM, Helsinki Institute of Life Sciences, University of Helsinki in Finland. Caroline’s research is focused on understanding the mechanisms driving disease progression and drug resistance in hematological malignancies. She also applies technologies for better translation of basic research results towards clinical implementation.
https://www.fimm.fi/en/research/groups/heckman
14.50-15.10 Coffee break
15.10-16.00 “The ABCs of a postdoc in the US” with M. Bishr Omary
This interactive session is open to all interested and will cover tips and advice on doing a postdoc in general and especially related to being a postdoc in US.
Register before Friday January 11th at https://survey.abo.fi/lomakkeet/10837/lomake.html
For more information, contact Diana Toivola, e-mail: diana.toivola@abo.fi
#December
Medisiina D, Sakari Alhopuro Lecture hall, Kiinamyllynkatu, Turku
Special guest seminar
Johan Hartman, Karolinska Institute, Sweden
Precision pathology – from molecule to drug development
Dr Hartman is a principal investigator at Karolinska Institutet, Dept of Oncology and Pathology. His research focuses on breast cancer diagnosis with emphasis on tumor heterogeneity and ex vivo drug profiling. He has co-published several papers on the role of heterogeneity and cancer stem cells for therapeutic resistance. His team also has interest in image analysis for histopathology. Proliferation is a central factor for breast tumorigenesis but also for subclassification of tumors. Hartmans team has worked many years to develop computer-assisted methods to classify breast cancers based on proliferation. Currently they are applying deep-learning algorithms to improve cancer diagnosis. Dr Hartman is a clinically active breast pathologist at Karolinska University Laboratory and head of the Swedish expert group in breast pathology (KVAST-bröstcancer).
Some selected papers:
Kim C, et al. Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing. Cell. 2018 May 3
Ullah I, et al. Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph-nodes. J Clin Invest. 2018 Apr 2
Ma R, et al. Estrogen receptor β as a therapeutic target in breast cancer stem cells. J Natl Cancer Inst. 2017 Mar 1
Rantalainen M, et al. Sci Rep. 2016 Nov 30.
Stålhammar G, et al. Digital image analysis outperforms manual biomarker assessment in breast cancer. Mod Pathol. 2016 Apr 29
“Cancer seminar: Precision pathology – from molecule to drug development”
Special guest seminar
Johan Hartman, Karolinska Institute, Sweden
Precision pathology – from molecule to drug development
Dr Hartman is a principal investigator at Karolinska Institutet, Dept of Oncology and Pathology. His research focuses on breast cancer diagnosis with emphasis on tumor heterogeneity and ex vivo drug profiling. He has co-published several papers on the role of heterogeneity and cancer stem cells for therapeutic resistance. His team also has interest in image analysis for histopathology. Proliferation is a central factor for breast tumorigenesis but also for subclassification of tumors. Hartmans team has worked many years to develop computer-assisted methods to classify breast cancers based on proliferation. Currently they are applying deep-learning algorithms to improve cancer diagnosis. Dr Hartman is a clinically active breast pathologist at Karolinska University Laboratory and head of the Swedish expert group in breast pathology (KVAST-bröstcancer).
Some selected papers:
Kim C, et al. Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing. Cell. 2018 May 3
Ullah I, et al. Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph-nodes. J Clin Invest. 2018 Apr 2
Ma R, et al. Estrogen receptor β as a therapeutic target in breast cancer stem cells. J Natl Cancer Inst. 2017 Mar 1
Rantalainen M, et al. Sci Rep. 2016 Nov 30.
Stålhammar G, et al. Digital image analysis outperforms manual biomarker assessment in breast cancer. Mod Pathol. 2016 Apr 29
Medisiina D, Lauren 2 lecture hall, Kiinamyllynkatu 10, Turku
Urpo Lamminmäki, University of Turku
Synthetic Antibodies – Affinity Tools for Unmet Needs
Host: Jukka Alinikula
“Mikro seminar: Synthetic Antibodies – Affinity Tools for Unmet Needs”Urpo Lamminmäki, University of Turku
Synthetic Antibodies – Affinity Tools for Unmet Needs
Host: Jukka Alinikula
Medisiina D, Säätiö Lecture room, Kiinamyllynkatu 10, Turku
Mikko Metsä-Ketelä, University of Turku
Development of C-nucleoside antibiotics for inhibition of bacterial RNA polymerases.
Host: Kirsi Gröndahl-Yli-Hannuksela.
“Mikro seminar: Development of C-nucleoside antibiotics for inhibition of bacterial RNA polymerases”Mikko Metsä-Ketelä, University of Turku
Development of C-nucleoside antibiotics for inhibition of bacterial RNA polymerases.
Host: Kirsi Gröndahl-Yli-Hannuksela.
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
Program:
14.45 Sparkling wine
15.15 Lauri Aaltonen, University of Helsinki – “Genome sequencing in intestinal cancer”
16.15 Johanna Hynninen, Turku University Hospital – “Ovarian Cancer – Clinical aspects and ongoing research projects”
16.50 PhD award –lecture
17.10 Snacks and drinks
Registrations by November 26 via email: contact-tcrs (at) lists.utu.fi
Please also indicate a possible special diet when registering.
Please renew your membership or become a member for 2018 by paying the 10 € annual membership fee on the Society’s bank account before the seminar (FI7612093000051335, Turun Syöpätutkijat Ry, please use your name as a refenrence).
“Cancer Research Seminar: Christmas seminar”Program:
14.45 Sparkling wine
15.15 Lauri Aaltonen, University of Helsinki – “Genome sequencing in intestinal cancer”
16.15 Johanna Hynninen, Turku University Hospital – “Ovarian Cancer – Clinical aspects and ongoing research projects”
16.50 PhD award –lecture
17.10 Snacks and drinks
Registrations by November 26 via email: contact-tcrs (at) lists.utu.fi
Please also indicate a possible special diet when registering.
Please renew your membership or become a member for 2018 by paying the 10 € annual membership fee on the Society’s bank account before the seminar (FI7612093000051335, Turun Syöpätutkijat Ry, please use your name as a refenrence).
#November
Medisiina D, Lauren 2 lecture hall, Kiinamyllynkatu 10, Turku
Ilona Rissanen, University of Helsinki
Molecular architecture of hantaviruses: keys to infection and virus neutralization
Host: Sisko Tauriainen.
“Mikro seminar: Molecular architecture of hantaviruses: keys to infection and virus neutralization”Ilona Rissanen, University of Helsinki
Molecular architecture of hantaviruses: keys to infection and virus neutralization
Host: Sisko Tauriainen.
Medisiina D, Lauren 2 lecture hall, Kiinamyllynkatu 10, Turku
Annukka Pietikäinen, University of Turku
Pathogenesis and diagnostics of Lyme borreliosis
Host: Jukka Hytönen.
“Mikro seminar: Pathogenesis and diagnostics of Lyme borreliosis”Annukka Pietikäinen, University of Turku
Pathogenesis and diagnostics of Lyme borreliosis
Host: Jukka Hytönen.
Ministeri auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Coffee/tea and snack available before the talks
The two speakers:
- Guido Serini (University of Torino Medical School)
- Title of talk: “Mechanisms of β1 integrin activation and clustering in the control of endothelial cell adhesion and migration”. This will be unpublished data.
- If time allows, Prof Serini will also summarise some recent work on semaphorin, its co-receptor neuropilin 1 and new binding partners and the implications of these novel interactions in vascular morphogenesis and function.
In his earlier work, Prof Serini showed for the first time how endothelial class 3 semaphorins (SEMA3) signal through plexin receptors to inhibit integrins and allow vascular morphogenesis (Serini et al., Nature 2003). More recently, his research group rationally designed, generated and characterized a mutant, protease resistant, and easily purifiable superagonist SEMA3A protein isoform that represents a parenterally-deliverable drug that effectively normalizes the cancer vasculature (Gioelli et al., Sci. Transl. Med. 2018). His lab has also unveiled how vascular morphogenesis relies not only on integrin conformational activation, but also on dedicated signalling pathways that control the endocytosis and recycling of conformationally active integrins to adhesion sites in coordination with TGN-dependent polarized fibronectin secretion (Valdembri et al., PloS Biol. 2009; Sandri et al., Cell Res. 2012; Mana et al., Nat. Commun. 2016).
Prof. Serini will serve as Pranshu Sahgal’s PhD opponent on Friday 16th November!
Selected publications (Guido Serini):
Semaphorins and angiogenesis
- G. Serini*, V. Valdembri, S. Zanivan, G. Morterra, C. Burkhardt, F. Caccavari, L. Zammataro, L. Primo, L. Tamagnone, M. Logan, M. Tessier-Lavigne, M. Taniguchi, A.W. Püschel, and F. Bussolino*. Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature 2003, 424: 391-397. *Shared corresponding authorship.
- F. Maione, F. Molla, C. Meda, R. Latini, L. Zentilin, M. Giacca, G. Seano, G. Serini*, F. Bussolino*, and E. Giraudo*. Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models. J. Clin. Invest. 2009, 119: 3356-3372. *Shared senior authorship.
- N. Gioelli, F. Maione, C. Camillo, M. Ghitti, D. Valdembri, N. Morello, M. Darche, L. Zentilin, G. Cagnoni, Y. Qiu, M. Giacca, M. Giustetto, M. Paques, I. Cascone, G. Musco, L. Tamagnone, E. Giraudo, and G. Serini. A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent. Sci. Transl. Med. 2018, 10: eaah4807.
Active integrin traffic
- D. Valdembri, P.T. Caswell, K.I. Anderson, J.P. Schwarz, I. König, E. Astanina, F. Caccavari, J.C. Norman, M.J. Humphries, F. Bussolino, and G. Serini. Neuropilin−1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells. PLoS Biology 2009, 7:e1000025.
- C. Sandri, F. Caccavari, D. Valdembri, C. Camillo, S. Veltel, M. Santambrogio, L. Lanzetti, F. Bussolino, J. Ivaska, and G. Serini. The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling. Cell Res. 2012, 22:1479-1501.
- G. Mana, F. Clapero, E. Panieri, V. Panero, R. T. Böttcher, H.Y. Tseng, F. Saltarin, E. Astanina, K.I. Wolanska, M. R. Morgan, M.J. Humphries, M.M. Santoro, G. Serini*, and D. Valdembri*. PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nat. Commun. 2016, 7: 13546. *Shared senior and corresponding authorship.
- Stephanie Miserey-Linkei (Institut Curie, PSL Research University)
- Title of talk: “Getting out the Golgi complex thanks to the RAB6 GTPase”
Dr Miserey-Linkei is a talented senior researcher in the group of Prof. Bruno Goud in Institut Curie. She investigates the mechanisms regulating cellular transport with a focus on unravelling the role of Rab GTPases, the Golgi network and microtubules in this important biological process.
Selected publications (Stephanie Miserey-Linkei):
- Miserey-Lenkei S, Bousquet H, Pylypenko O, Bardin S, Dimitrov A, Bressanelli, G, Bonifay R, Fraisier V, Guillou C, Bougeret C, Houdusse A, Echard A, Goud B. Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions. Nat Commun. 2017, 8(1):1254.
- Patwardhan A, Bardin S, Miserey-Lenkei S, Larue L, Goud B, Raposo G, Delevoye C. Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes. Nat Commun. 2017, 8:15835.
- Miserey-Lenkei S, Colombo MI. Small RAB GTPases Regulate Multiple Steps of Mitosis. Front Cell Dev Biol. 2016, 4:2. Review.
- Delevoye C, Miserey-Lenkei S, Montagnac G, Gilles-Marsens F, Paul-Gilloteaux P, Giordano F, Waharte F, Marks MS, Goud B, Raposo G. Recycling endosome tubule morphogenesis from sorting endosomes requires the kinesin motor KIF13A. Cell Rep. 2014, 6(3):445-54.
- Al Awabdh S, Miserey-Lenkei S, Bouceba T, Masson J, Kano F, Marinach-Patrice C, Hamon M, Emerit MB, Darmon M. A new vesicular scaffolding complex mediates the G-protein-coupled 5-HT1A receptor targeting to neuronal dendrites. J Neurosci. 2012, 32(41):14227-41.
- Miserey-Lenkei S, Waharte F, Boulet A, Cuif MH, Tenza D, El Marjou A, Raposo G, Salamero J, Héliot L, Goud B, Monier S. Rab6-interacting protein 1 links Rab6 and Rab11 function. Traffic. 2007, 8(10):1385-403.
- Miserey-Lenkei S, Couëdel-Courteille A, Del Nery E, Bardin S, Piel M, Racine V, Sibarita JB, Perez F, Bornens M, Goud B. A role for the Rab6A’ GTPase in the inactivation of the Mad2-spindle checkpoint. EMBO J. 2006, 25(2):278-89.
Coffee/tea and snack available before the talks
The two speakers:
- Guido Serini (University of Torino Medical School)
- Title of talk: “Mechanisms of β1 integrin activation and clustering in the control of endothelial cell adhesion and migration”. This will be unpublished data.
- If time allows, Prof Serini will also summarise some recent work on semaphorin, its co-receptor neuropilin 1 and new binding partners and the implications of these novel interactions in vascular morphogenesis and function.
In his earlier work, Prof Serini showed for the first time how endothelial class 3 semaphorins (SEMA3) signal through plexin receptors to inhibit integrins and allow vascular morphogenesis (Serini et al., Nature 2003). More recently, his research group rationally designed, generated and characterized a mutant, protease resistant, and easily purifiable superagonist SEMA3A protein isoform that represents a parenterally-deliverable drug that effectively normalizes the cancer vasculature (Gioelli et al., Sci. Transl. Med. 2018). His lab has also unveiled how vascular morphogenesis relies not only on integrin conformational activation, but also on dedicated signalling pathways that control the endocytosis and recycling of conformationally active integrins to adhesion sites in coordination with TGN-dependent polarized fibronectin secretion (Valdembri et al., PloS Biol. 2009; Sandri et al., Cell Res. 2012; Mana et al., Nat. Commun. 2016).
Prof. Serini will serve as Pranshu Sahgal’s PhD opponent on Friday 16th November!
Selected publications (Guido Serini):
Semaphorins and angiogenesis
- G. Serini*, V. Valdembri, S. Zanivan, G. Morterra, C. Burkhardt, F. Caccavari, L. Zammataro, L. Primo, L. Tamagnone, M. Logan, M. Tessier-Lavigne, M. Taniguchi, A.W. Püschel, and F. Bussolino*. Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature 2003, 424: 391-397. *Shared corresponding authorship.
- F. Maione, F. Molla, C. Meda, R. Latini, L. Zentilin, M. Giacca, G. Seano, G. Serini*, F. Bussolino*, and E. Giraudo*. Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models. J. Clin. Invest. 2009, 119: 3356-3372. *Shared senior authorship.
- N. Gioelli, F. Maione, C. Camillo, M. Ghitti, D. Valdembri, N. Morello, M. Darche, L. Zentilin, G. Cagnoni, Y. Qiu, M. Giacca, M. Giustetto, M. Paques, I. Cascone, G. Musco, L. Tamagnone, E. Giraudo, and G. Serini. A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent. Sci. Transl. Med. 2018, 10: eaah4807.
Active integrin traffic
- D. Valdembri, P.T. Caswell, K.I. Anderson, J.P. Schwarz, I. König, E. Astanina, F. Caccavari, J.C. Norman, M.J. Humphries, F. Bussolino, and G. Serini. Neuropilin−1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells. PLoS Biology 2009, 7:e1000025.
- C. Sandri, F. Caccavari, D. Valdembri, C. Camillo, S. Veltel, M. Santambrogio, L. Lanzetti, F. Bussolino, J. Ivaska, and G. Serini. The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling. Cell Res. 2012, 22:1479-1501.
- G. Mana, F. Clapero, E. Panieri, V. Panero, R. T. Böttcher, H.Y. Tseng, F. Saltarin, E. Astanina, K.I. Wolanska, M. R. Morgan, M.J. Humphries, M.M. Santoro, G. Serini*, and D. Valdembri*. PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nat. Commun. 2016, 7: 13546. *Shared senior and corresponding authorship.
- Stephanie Miserey-Linkei (Institut Curie, PSL Research University)
- Title of talk: “Getting out the Golgi complex thanks to the RAB6 GTPase”
Dr Miserey-Linkei is a talented senior researcher in the group of Prof. Bruno Goud in Institut Curie. She investigates the mechanisms regulating cellular transport with a focus on unravelling the role of Rab GTPases, the Golgi network and microtubules in this important biological process.
Selected publications (Stephanie Miserey-Linkei):
- Miserey-Lenkei S, Bousquet H, Pylypenko O, Bardin S, Dimitrov A, Bressanelli, G, Bonifay R, Fraisier V, Guillou C, Bougeret C, Houdusse A, Echard A, Goud B. Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions. Nat Commun. 2017, 8(1):1254.
- Patwardhan A, Bardin S, Miserey-Lenkei S, Larue L, Goud B, Raposo G, Delevoye C. Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes. Nat Commun. 2017, 8:15835.
- Miserey-Lenkei S, Colombo MI. Small RAB GTPases Regulate Multiple Steps of Mitosis. Front Cell Dev Biol. 2016, 4:2. Review.
- Delevoye C, Miserey-Lenkei S, Montagnac G, Gilles-Marsens F, Paul-Gilloteaux P, Giordano F, Waharte F, Marks MS, Goud B, Raposo G. Recycling endosome tubule morphogenesis from sorting endosomes requires the kinesin motor KIF13A. Cell Rep. 2014, 6(3):445-54.
- Al Awabdh S, Miserey-Lenkei S, Bouceba T, Masson J, Kano F, Marinach-Patrice C, Hamon M, Emerit MB, Darmon M. A new vesicular scaffolding complex mediates the G-protein-coupled 5-HT1A receptor targeting to neuronal dendrites. J Neurosci. 2012, 32(41):14227-41.
- Miserey-Lenkei S, Waharte F, Boulet A, Cuif MH, Tenza D, El Marjou A, Raposo G, Salamero J, Héliot L, Goud B, Monier S. Rab6-interacting protein 1 links Rab6 and Rab11 function. Traffic. 2007, 8(10):1385-403.
- Miserey-Lenkei S, Couëdel-Courteille A, Del Nery E, Bardin S, Piel M, Racine V, Sibarita JB, Perez F, Bornens M, Goud B. A role for the Rab6A’ GTPase in the inactivation of the Mad2-spindle checkpoint. EMBO J. 2006, 25(2):278-89.
Medisiina D, Lauren 2 lecture hall, Kiinamyllynkatu 10, Turku
Tomas Strandin, University of Helsinki
The role of endothelial cells in hantavirus pathogenesis.
Host: Pekka Kolehmainen
“Mikro seminar: The role of endothelial cells in hantavirus pathogenesis”Tomas Strandin, University of Helsinki
The role of endothelial cells in hantavirus pathogenesis.
Host: Pekka Kolehmainen
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
Jari Nuutila, Päivi Jalava-Karvinen, University of Turku and University Hospital Turku
Flow cytometry in infection diagnostics.
Host: Sisko Tauriainen.
“Mikro seminar: Flow cytometry in infection diagnostics”Jari Nuutila, Päivi Jalava-Karvinen, University of Turku and University Hospital Turku
Flow cytometry in infection diagnostics.
Host: Sisko Tauriainen.
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
Csilla Sipeky: Aggressive prostate cancer: from genetic basis to clinical translation
Pauliina Hartiala: Lymfactin trial – Combined adenoviral VEGF-C and lymph node transfer treatment for patients with breast cancer treatment associated lymphedema
“Cancer Research Seminar: Csilla Sipeky and Pauliina Hartiala”Csilla Sipeky: Aggressive prostate cancer: from genetic basis to clinical translation
Pauliina Hartiala: Lymfactin trial – Combined adenoviral VEGF-C and lymph node transfer treatment for patients with breast cancer treatment associated lymphedema
#October
Medisiina D, Sakari Alhopuro Lecture hall, Kiinamyllynkatu, Turku
Welcome words by the Dean, coffee, cake and sparkling wine. Music by Aura Brass Band in Medisiina D lobby
Opening programme (in Finnish) on Monday, 8 October at 2pm in Sakari Alhopuro lecture hall in Medisiina D
KUN LÄÄKETIEDE KOHTASI POLITIIKAN – YHTEISKUNNALLISIA PAINEITA LÄÄKETIETEELLISEN TIEDEKUNNAN VAIHEISSA
Vesa Vares, Professor of Political History, UTU
LÄÄKETIETEELLISEN TIEDEKUNNAN TÄHTIHETKIÄ JA TAITEKOHTIA
Timo Niitemaa, M.Soc.Sci, Communications Officer (emeritus), UTU
TULEVAISUUDEN NÄKYMIÄ
Markku Wilenius, Professor of Futures Studies UTU
Welcome to join the festive activities!
Programme of the festival week
“Grand Opening of the 75th Anniversary Festival Week of the Faculty of Medicine”Welcome words by the Dean, coffee, cake and sparkling wine. Music by Aura Brass Band in Medisiina D lobby
Opening programme (in Finnish) on Monday, 8 October at 2pm in Sakari Alhopuro lecture hall in Medisiina D
KUN LÄÄKETIEDE KOHTASI POLITIIKAN – YHTEISKUNNALLISIA PAINEITA LÄÄKETIETEELLISEN TIEDEKUNNAN VAIHEISSA
Vesa Vares, Professor of Political History, UTU
LÄÄKETIETEELLISEN TIEDEKUNNAN TÄHTIHETKIÄ JA TAITEKOHTIA
Timo Niitemaa, M.Soc.Sci, Communications Officer (emeritus), UTU
TULEVAISUUDEN NÄKYMIÄ
Markku Wilenius, Professor of Futures Studies UTU
Welcome to join the festive activities!
T-Hospital, Haartman Lecture Hall, Savitehtaankatu 1, Turku
Eleonora Mäkelä: Novel diagnostic markers in AML
Mari Suominen: Radium-223 dichloride as a dual inhibitor of the vicious cycle and tumor growth in breast and prostate cancer bone metastasis models
“Cancer seminar: Eleonora Mäkelä and Mari Suominen”Eleonora Mäkelä: Novel diagnostic markers in AML
Mari Suominen: Radium-223 dichloride as a dual inhibitor of the vicious cycle and tumor growth in breast and prostate cancer bone metastasis models
#September
Turku Centre for Biotechnology, 5th floor seminar room, BioCity B-staircase, Tykistökatu 6, Turku
Medisiina D, Lauren 1 Lecture Hall, Kiinamyllynkatu, Turku
Dr. Hans Hendriks, Hendriks Pharmaceutical Consulting
Coffee served at 14:45
Hans Hendriks, Ph.D., held positions in Cell Biology and Immunology at the Vrije Universiteit (Amsterdam, The Netherlands). After 17 years he joined the New Drug Development Office (now part of INC Research), Europe’s foremost oncology Contract Research Organisation (Amsterdam, The Netherlands), gaining 12 years experience leading international drug discovery and development collaborations. In addition, he served in various drug development and drug evaluation committees of the EORTC, Cancer Research UK and US National Cancer Institute, and held for 8 years a position in the Executive Board of the EORTC Biological Therapeutics Development Group.
He established Hendriks Pharmaceutical Consulting January 2000, an independent consultancy company providing services to small companies and biotechs in Oncology R&D. He is co-founder of the Biotherapy Development Association (Germany, 2001) and served on the Scientific Advisory Board of a German biotech company (2001-2003). He was the National Network Representative for The Netherlands in the Council of the European Association for Cancer Research (EACR), period 2013-2018, and received a honorary EACR membership as of 2018.
From 2002-2006 Dr. Hendriks acted as Project Technical Assistant to the European Commission (DG Research) in the 5th Framework Programme (FP) overseeing 20 cancer-related EU-funded projects, served as expert evaluator in 5th, 6th, 7th FP and H2020 of the EU and acted as Administrative Manager for the FP6 CompuVac project (June 2008-October 2009). In addition, he assisted Austrian, Dutch, Italian, and Slovenian consortia in the preparation and submission of grant applications for the European Union’s 7th FP, H2020 and the Innovative Medicines Initiative 2.
He was successful in bringing the telomere targeting agent KML001 from early stage preclinical research to Phase I clinical studies (CCR 2008;14:4593-602) and is co-inventor of a US patent application (2009).
Hendriks Pharmaceutical Consulting is member of the Competence Network Life Science (www.conelis.org), an association of selected life science experts that provides top-tier consulting services to the pharmaceutical industry. It is a network of highly qualified and independent experts who can be contracted individually or as part of an interdisciplinary team.
Selected publications
Hendriks. H. et al., Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative, British Journal of Cancer, 2017.
Peters, GJ., Govaerts, A-S., Hendriks, H. for the EORTC-pharmacology and molecular mechanism group. The role of pharmacology in anticancer drug development, ADMET, 2018
“Cancer Seminar Series: Pharmacology directed strategies in anticancer drug development, a viable approach for academia?”Dr. Hans Hendriks, Hendriks Pharmaceutical Consulting
Coffee served at 14:45
Hans Hendriks, Ph.D., held positions in Cell Biology and Immunology at the Vrije Universiteit (Amsterdam, The Netherlands). After 17 years he joined the New Drug Development Office (now part of INC Research), Europe’s foremost oncology Contract Research Organisation (Amsterdam, The Netherlands), gaining 12 years experience leading international drug discovery and development collaborations. In addition, he served in various drug development and drug evaluation committees of the EORTC, Cancer Research UK and US National Cancer Institute, and held for 8 years a position in the Executive Board of the EORTC Biological Therapeutics Development Group.
He established Hendriks Pharmaceutical Consulting January 2000, an independent consultancy company providing services to small companies and biotechs in Oncology R&D. He is co-founder of the Biotherapy Development Association (Germany, 2001) and served on the Scientific Advisory Board of a German biotech company (2001-2003). He was the National Network Representative for The Netherlands in the Council of the European Association for Cancer Research (EACR), period 2013-2018, and received a honorary EACR membership as of 2018.
From 2002-2006 Dr. Hendriks acted as Project Technical Assistant to the European Commission (DG Research) in the 5th Framework Programme (FP) overseeing 20 cancer-related EU-funded projects, served as expert evaluator in 5th, 6th, 7th FP and H2020 of the EU and acted as Administrative Manager for the FP6 CompuVac project (June 2008-October 2009). In addition, he assisted Austrian, Dutch, Italian, and Slovenian consortia in the preparation and submission of grant applications for the European Union’s 7th FP, H2020 and the Innovative Medicines Initiative 2.
He was successful in bringing the telomere targeting agent KML001 from early stage preclinical research to Phase I clinical studies (CCR 2008;14:4593-602) and is co-inventor of a US patent application (2009).
Hendriks Pharmaceutical Consulting is member of the Competence Network Life Science (www.conelis.org), an association of selected life science experts that provides top-tier consulting services to the pharmaceutical industry. It is a network of highly qualified and independent experts who can be contracted individually or as part of an interdisciplinary team.
Selected publications
Hendriks. H. et al., Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative, British Journal of Cancer, 2017.
Peters, GJ., Govaerts, A-S., Hendriks, H. for the EORTC-pharmacology and molecular mechanism group. The role of pharmacology in anticancer drug development, ADMET, 2018
#August
Turku Centre for Biotechnology, 5th floor seminar room, BioCity B-staircase, Tykistökatu 6, Turku
Dr. Wah Ing Goh, the Agency for Science, Technology and Research (A*STAR) Microscopy Platform
Host: Camilo Guzman
Dear all,
We would like to invite you to a special seminar by (https://www.a-star.edu.sg/imb/Tech-Platforms/IMB-Microscopy-Unit) in Singapore. Her seminar is entitled “The A*STAR Microscopy Platform and SingaScope – a microscopy core facility network for Singapore”. The seminar will take place in the TBC seminar room on the 5th Floor (Bio 5034a) and it is scheduled for Thursday 16th of August at 2:00 PM.
Dr. Goh is visiting the TBC as part of the “Job Shadowing International Program” of the Global BioImaging project and he will be shadowing our activities in bio imaging and promoting and active exchange between the Agency for Science, Technology and Research (A*STAR) and our Finnish ALM Node of Euro-BioImaging
For detailed information please see attached PDF file.
See you all there!
“Special seminar: The A*STAR Microscopy Platform and SingaScope – a microscopy core facility network for Singapore”Dr. Wah Ing Goh, the Agency for Science, Technology and Research (A*STAR) Microscopy Platform
Host: Camilo Guzman
Dear all,
We would like to invite you to a special seminar by (https://www.a-star.edu.sg/imb/Tech-Platforms/IMB-Microscopy-Unit) in Singapore. Her seminar is entitled “The A*STAR Microscopy Platform and SingaScope – a microscopy core facility network for Singapore”. The seminar will take place in the TBC seminar room on the 5th Floor (Bio 5034a) and it is scheduled for Thursday 16th of August at 2:00 PM.
Dr. Goh is visiting the TBC as part of the “Job Shadowing International Program” of the Global BioImaging project and he will be shadowing our activities in bio imaging and promoting and active exchange between the Agency for Science, Technology and Research (A*STAR) and our Finnish ALM Node of Euro-BioImaging
For detailed information please see attached PDF file.
See you all there!
#May
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Klaus Hedman, University of Helsinki
Host: Sisko Tauriainen
“MIKRO seminars: Hunting ancestral viruses in ancient tissue remains”Klaus Hedman, University of Helsinki
Host: Sisko Tauriainen
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
FinLAS (Suomen koe-eläintieteen yhdistys ry) järjestää kevätseminaarin 18.5.2018 Turussa. Seminaari on tarkoitettu kaikille koe-eläinten parissa työskenteleville, koe-eläinalan ammattilaisille, tutkijoille ja opiskelijoille. Tapahtuma tarkempi ohjelma on tässä, ja kevätseminaarissa pääsemme kuulemaan koe-eläinkeskuksen johtajan Ulla-Marjut Jaakkolan läksiäisluennon.
Ilmoittautuminen: https://www.webropolsurveys.com/S/B9CD93BC3F165132.par
Lisätietoa: Emrah Yatkin (emryat@utu.fi)
“FinLAS-KEK kevätseminaari: Tiede ja tunteet”FinLAS (Suomen koe-eläintieteen yhdistys ry) järjestää kevätseminaarin 18.5.2018 Turussa. Seminaari on tarkoitettu kaikille koe-eläinten parissa työskenteleville, koe-eläinalan ammattilaisille, tutkijoille ja opiskelijoille. Tapahtuma tarkempi ohjelma on tässä, ja kevätseminaarissa pääsemme kuulemaan koe-eläinkeskuksen johtajan Ulla-Marjut Jaakkolan läksiäisluennon.
Ilmoittautuminen: https://www.webropolsurveys.com/S/B9CD93BC3F165132.par
Lisätietoa: Emrah Yatkin (emryat@utu.fi)
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Matti Waris, University of Turku
Host: Ilkka Julkunen
“MIKRO seminars: Host biomarkers of respiratory virus infections”Matti Waris, University of Turku
Host: Ilkka Julkunen
pub3 auditorium, Publicum, Assistentinkatu 7, Turku
Finnish Society for Bioinformatics is arranging a yearly Bioinformatics day, and the program includes lectures, poster session and workshops. The topics of the lectures are dealing with current bioinformatics research including both biosciences and computational modeling. This event gathers together people working with bioinformatics, both from universities and from companies around Finland.
Program of the event is available here.
Registration to the event from here.
“Bioinformatics day 2018”Finnish Society for Bioinformatics is arranging a yearly Bioinformatics day, and the program includes lectures, poster session and workshops. The topics of the lectures are dealing with current bioinformatics research including both biosciences and computational modeling. This event gathers together people working with bioinformatics, both from universities and from companies around Finland.
Program of the event is available here.
Registration to the event from here.
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Ilkka Julkunen, University of Turku
Host: Laura Kakkola
“MIKRO seminars: Human macrophages and DCs, receptors, signaling and activation of innate immunity”Ilkka Julkunen, University of Turku
Host: Laura Kakkola
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Prof. John Lemasters
GlaxoSmithKline Distinguished Endowed Chair
Director, Center for Cell Death, Injury & Regeneration
Departments of Drug Discovery & Biomedical Sciences and Biochemistry & Molecular Biology
Medical University of South Carolina, USA
Host: Eeva-Liisa Eskelinen (eeva-liisa.eskelinen@utu.fi)
In case you wish to meet with Prof. Lemasters, please contact the host.
Dr. Lemasters’ research interests include the cellular and molecular mechanisms underlying toxic, hypoxic and ischemia-reperfusion injury to liver and heart. His laboratory applies new techniques of laser scanning confocal and multiphoton microscopy to characterize the physiology of single living cells, including the assessment of ion homeostasis, chelatable iron, mitochondrial function, electrical potentials, oxygen and nitrogen free radical formation, membrane permeability and other biochemical parameters during the pathogenesis of lethal cell injury.
Selected publications
DeHart DN, Fang D, Heslop K, Li L, Lemasters JJ, Maldonado EN. Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells. Biochem Pharmacol. 2018 Feb;148:155-162. doi: 10.1016/j.bcp.2017.12.022. Epub 2017 Dec 28.
Maldonado EN, DeHart DN, Patnaik J, Klatt SC, Gooz MB, Lemasters JJ. ATP/ADP turnover and import of glycolytic ATP into mitochondria in cancer cells is independent of the adenine nucleotide translocator. J Biol Chem. 2017 Oct 13;292(41):16969. doi: 10.1074/jbc.A116.734814.
Teplova VV, Kruglov AG, Kovalyov LI, Nikiforova AB, Fedotcheva NI, Lemasters JJ. Glutamate contributes to alcohol hepatotoxicity by enhancing oxidative stress in mitochondria. J Bioenerg Biomembr. 2017 Jun;49(3):253-264. doi: 10.1007/s10863-017-9713-0. Epub 2017 May 6.
Liu Q, H Rehman, Y Krishnasamy, RG Schnellmann, JJ Lemasters and Z Zhong. Improvement of liver injury and survival by JNK2 and iNOS deficiency in liver transplants from cardiac death mice. J Hepatol 2015, 63:68-74.
“Special seminar: Types and Initiators of Mitochondrial Autophagy (Mitophagy)”
Prof. John Lemasters
GlaxoSmithKline Distinguished Endowed Chair
Director, Center for Cell Death, Injury & Regeneration
Departments of Drug Discovery & Biomedical Sciences and Biochemistry & Molecular Biology
Medical University of South Carolina, USA
Host: Eeva-Liisa Eskelinen (eeva-liisa.eskelinen@utu.fi)
In case you wish to meet with Prof. Lemasters, please contact the host.
Dr. Lemasters’ research interests include the cellular and molecular mechanisms underlying toxic, hypoxic and ischemia-reperfusion injury to liver and heart. His laboratory applies new techniques of laser scanning confocal and multiphoton microscopy to characterize the physiology of single living cells, including the assessment of ion homeostasis, chelatable iron, mitochondrial function, electrical potentials, oxygen and nitrogen free radical formation, membrane permeability and other biochemical parameters during the pathogenesis of lethal cell injury.
Selected publications
DeHart DN, Fang D, Heslop K, Li L, Lemasters JJ, Maldonado EN. Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells. Biochem Pharmacol. 2018 Feb;148:155-162. doi: 10.1016/j.bcp.2017.12.022. Epub 2017 Dec 28.
Maldonado EN, DeHart DN, Patnaik J, Klatt SC, Gooz MB, Lemasters JJ. ATP/ADP turnover and import of glycolytic ATP into mitochondria in cancer cells is independent of the adenine nucleotide translocator. J Biol Chem. 2017 Oct 13;292(41):16969. doi: 10.1074/jbc.A116.734814.
Teplova VV, Kruglov AG, Kovalyov LI, Nikiforova AB, Fedotcheva NI, Lemasters JJ. Glutamate contributes to alcohol hepatotoxicity by enhancing oxidative stress in mitochondria. J Bioenerg Biomembr. 2017 Jun;49(3):253-264. doi: 10.1007/s10863-017-9713-0. Epub 2017 May 6.
Liu Q, H Rehman, Y Krishnasamy, RG Schnellmann, JJ Lemasters and Z Zhong. Improvement of liver injury and survival by JNK2 and iNOS deficiency in liver transplants from cardiac death mice. J Hepatol 2015, 63:68-74.
Kurssalen, ÅAU Cell Biology, Biocity 2nd floor, Tykistökatu 6, Turku
Nicholas Kurniawan (PhD; assistant professor in biomedical engineering) and Aref Saberi (BSc) from the Eindhoven University of Technology (TU/e) will present their research as well as research and study opportunities available at their university next week at ÅAU Cell Biology.
Host: prof. Cecilia Sahlgren
13.15-14:00 Dr. Nicholas Kurniawan, Assistant professor in biomedical engineering, Eindhoven University of Technology (TU/e): Mechanobiology and tissue engineering
Dr. Kurniawan will present his research focused on the biophysical and mechanobiological aspects of cell-matrix interactions and related applications in regenerative medicine. In his research he combines expertise in biopolymer physics, cell biomechanics, and cytoskeletal rheology.
14:15-15:00 Aref Saberi, Eindhoven University of Technology (TU/e): Research activities and MSc programmes at Eindhoven University of Technology
An overview of research activities, educational programmes and student life at TU/e. The presentation is directed especially at students and researchers interested in doing an exchange abroad.
Kurniawan and Saberi will also give a lecture on stem cells and mechanosignaling on the ÅAU Stem cells course (223001.0) at 10-12 on the same day (in Kurssalen). Everyone interested is welcome to take part in the lecture as well.
“Special seminar: Mechanobiological research and study opportunities at Eindhoven University of Technology”Nicholas Kurniawan (PhD; assistant professor in biomedical engineering) and Aref Saberi (BSc) from the Eindhoven University of Technology (TU/e) will present their research as well as research and study opportunities available at their university next week at ÅAU Cell Biology.
Host: prof. Cecilia Sahlgren
13.15-14:00 Dr. Nicholas Kurniawan, Assistant professor in biomedical engineering, Eindhoven University of Technology (TU/e): Mechanobiology and tissue engineering
Dr. Kurniawan will present his research focused on the biophysical and mechanobiological aspects of cell-matrix interactions and related applications in regenerative medicine. In his research he combines expertise in biopolymer physics, cell biomechanics, and cytoskeletal rheology.
14:15-15:00 Aref Saberi, Eindhoven University of Technology (TU/e): Research activities and MSc programmes at Eindhoven University of Technology
An overview of research activities, educational programmes and student life at TU/e. The presentation is directed especially at students and researchers interested in doing an exchange abroad.
Kurniawan and Saberi will also give a lecture on stem cells and mechanosignaling on the ÅAU Stem cells course (223001.0) at 10-12 on the same day (in Kurssalen). Everyone interested is welcome to take part in the lecture as well.
#April
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Tapio Lönnberg, Turku Centre for Biotechnology
Host: Raine Toivonen
“MIKRO seminars: Single-cell transcriptomics and T cell fate decisions”Tapio Lönnberg, Turku Centre for Biotechnology
Host: Raine Toivonen
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Juha Vuononvirta, Imperial College of London
Host: Alex-Mikael Barkoff
“CANCELLED: MIKRO seminars: In vivo imaging of neutrophilic inflammation in murine lung”Juha Vuononvirta, Imperial College of London
Host: Alex-Mikael Barkoff
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Minna Poranen, University of Helsinki
Host: Veijo Hukkanen
“MIKRO seminars: Genome replication by double-stranded RNA viruses and phages: from molecular mechanisms to RNAi applications”Minna Poranen, University of Helsinki
Host: Veijo Hukkanen
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Arno Hänninen, Univeristy of Turku
Host: Raine Toivonen
“MIKRO seminars: Proteomics approach to study gut microbia and its relevance in type 1 diabetes”Arno Hänninen, Univeristy of Turku
Host: Raine Toivonen
#March
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Manu Tamminen, University of Turku
Host: Kirsi Gröndahl-Yli-Hannuksela
“MIKRO seminars: Understanding antibiotic resistance using next-generation DNA sequencing”Manu Tamminen, University of Turku
Host: Kirsi Gröndahl-Yli-Hannuksela
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Karolina Louvanto, University Hospital of Turku, University of Turku
Host: Stina Syrjänen
“MIKRO seminars: HLA-G role in the natural history of HPV infection”Karolina Louvanto, University Hospital of Turku, University of Turku
Host: Stina Syrjänen
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Jaana Vuopio, University of Turku
Host: to be announced
“MIKRO seminars: Switching dynamics of MRSA – from healthcare to community”Jaana Vuopio, University of Turku
Host: to be announced
#February
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Tiina Nokireki, Finnish Food Safety Authority
Host: Tytti Vuorinen
“MIKRO seminars: Bat rabies in Turku area”
Tiina Nokireki, Finnish Food Safety Authority
Host: Tytti Vuorinen
Auditorium Beta, ICT-building, Joukahaisenkatu 3-5, Turku
BioCity research programme seminar, organized jointly by LIFESPAN and Receptor Programme and Turku Brain and Mind Center
Prof. Ulrik Gether, University of Copenhagen
The dopamine transporter: a key player in psychostimulant addiction and dopaminergic pathologies
Dr. Volker Eulenburg, University Hospital Leipzig, Clinics for Anaesthesiology and Intensive Care Medicine
Glycine transporter function in retina and dorsal horn – GlyT1 as a major regulator of glycine dependent neurotransmission
Host: Mika Scheinin (mschein@utu.fi)
Coffee/tea will be served at 15:00
“LIFESPAN and Receptor programme seminar: Ulrik Gether and Volker Eulenberg”BioCity research programme seminar, organized jointly by LIFESPAN and Receptor Programme and Turku Brain and Mind Center
Prof. Ulrik Gether, University of Copenhagen
The dopamine transporter: a key player in psychostimulant addiction and dopaminergic pathologies
Dr. Volker Eulenburg, University Hospital Leipzig, Clinics for Anaesthesiology and Intensive Care Medicine
Glycine transporter function in retina and dorsal horn – GlyT1 as a major regulator of glycine dependent neurotransmission
Host: Mika Scheinin (mschein@utu.fi)
Coffee/tea will be served at 15:00
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Minna Niemelä, Turku Centre for Biotechnology
Host: Raine Toivonen
“MIKRO seminars: Genomics services available for biomedical research at FFGC”Minna Niemelä, Turku Centre for Biotechnology
Host: Raine Toivonen
#January
Dentalia, Dent 1, Lemminkäisenkatu 2, Turku
This seminar is cancelled
Tapio Lönnberg, Turku Centre for Biotechnology
Host: Raine Toivonen
“CANCELLED: MIKRO seminars: Single-cell transcriptomics and T cell fate decisions”This seminar is cancelled
Tapio Lönnberg, Turku Centre for Biotechnology
Host: Raine Toivonen
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Manu Tamminen, University of Turku
Host: Kirsi Gröndahl-Yli-Hannuksela
“CANCELLED: MIKRO seminars: Understanding antibiotic resistance using next-generation DNA sequencing”Manu Tamminen, University of Turku
Host: Kirsi Gröndahl-Yli-Hannuksela
#December
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. John Marshall, Barts Cancer Institute, London, UK
“FoS: Development of imaging and therapy of cancer by targeting integrin alpha-v beta-6”Prof. John Marshall, Barts Cancer Institute, London, UK
Host: Johanna Ivaska
Prof. John Marshall has been studying the biology of tumour invasion for the last 25 years with a particular interest in the contributions made by the principal cell-matrix adhesion molecules called integrins. Prof Marshall’s group have identified integrin αvβ6, an epithelial-specific integrin not detectable on most normal tissues, as an important new therapeutic target in many cancers. In addition to understanding the function of the αvβ6 receptor in cancer, his group recently launched a clinical trial, in collaboration with Imanova to test the efficacy of an αvβ6-specific peptide for imaging solid cancers.
Selected publications
Raab-Westphal S, Marshall JF, Goodman SL. Integrins as Therapeutic Targets: Successes and Cancers. 2017 Cancers (Basel) 9(9).
Whilding LM, Parente-Pereira AC, Zabinski T, Davies DM, Petrovic RM, Kao YV, Saxena SA, Romain A, Costa-Guerra JA, Violette S, Itamochi H, Ghaem-Maghami S, Vallath S, Marshall JF, Maher J. Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells. (2017) Mol Ther. 25(1):259-273
Moore KM, Thomas GJ, Duffy SW et al. Therapeutic targeting of integrin αvβ6 in breast cancer. (2014) J Natl Cancer Inst vol. 106, (8)
Allen MD, Thomas GJ, Clark S et al. Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence. (2014) Clin Cancer Res (2) 344-357
Morgan MR, Jazayeri M, Ramsay AG, Thomas GJ, Boulanger MJ, Hart IR, Marshall JF. Psoriasin (S100A7) associates with integrin β6 subunit and is required for αvβ6-dependent carcinoma cell invasion. (2011) Oncogene 30(12):1422-35
Saha A, Ellison D, Thomas GJ, Vallath S, Mather SJ, Hart IR and Marshall JF. High resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin αvβ6. (2010) J Path. 222:52-63
Lambda auditorium, ICT building, Joukahaisenkatu 3-5, Turku
You are warmly welcome to the Turku Cancer Research Society’s Christmas Seminar!
Topic of the seminar will be colorectal cancer and we have speakers presenting both basic research and clinical aspects.
Program
16.00 Welcome
PhD Thesis of the Year Award
-Break for snacks and drinks-
17.00 Annika Ålgars (Turku University Hospital)
“An oncologists perspective to CRC and a glimpse into own research data”
17.30 Diana Toivola (Åbo Akademi University)
“Colorectal cancer – Keratins in disease mechanism and disease modeling”
17.50 Elli Narvi (University of Turku)
“Response to EGFR inhibition plus oxaliplatin is determined by the sequence of administration in colorectal cancer”
You are warmly welcome to the Turku Cancer Research Society’s Christmas Seminar!
Topic of the seminar will be colorectal cancer and we have speakers presenting both basic research and clinical aspects.
Program
16.00 Welcome
PhD Thesis of the Year Award
-Break for snacks and drinks-
17.00 Annika Ålgars (Turku University Hospital)
“An oncologists perspective to CRC and a glimpse into own research data”
17.30 Diana Toivola (Åbo Akademi University)
“Colorectal cancer – Keratins in disease mechanism and disease modeling”
17.50 Elli Narvi (University of Turku)
“Response to EGFR inhibition plus oxaliplatin is determined by the sequence of administration in colorectal cancer”
Dentalia, Dent 1, Lemminkäisenkatu 2, Turku
MIKRO Seminars of Infection Biology and Infectious Diseases
Tuija Kantala, University of Turku
Host: Matti Waris
“MIKRO seminars: Hepatitis E virus in Finland in pigs and humans”MIKRO Seminars of Infection Biology and Infectious Diseases
Tuija Kantala, University of Turku
Host: Matti Waris
Turku Centre for Biotechnology, 5th floor seminar room, BioCity B-staircase, Tykistökatu 6, Turku
Adjunct Prof. Timo Myöhänen, Drug Research Program, University of Helsinki
Host: Jukka Westermarck
Timo Myöhänen got his PhD (Pharmacology) in 2008 at University of Kuopio, and thereafter had post-doctoral visits in University of Antwerp (Belgium) and Georgetown University (Washington DC, USA) in 2010 and 2012. Dr. Myöhänen established his research group into Division of Pharmacology and Pharmacotherapy in University of Helsinki in 2011, got docentship in pharmacology in 2012 and is currently holding an Academy of Finland Research Fellow position. His research has focused on impact of a serine protease, prolyl oligopeptidase (PREP) and its pharmacological inhibition, on aggregation and toxicity of alpha-synuclein, a possible key player in cellular toxicity on Parkinson’s disease. Recent studies of Myöhänen lab have shown that PREP inhibitors can reduce the aggregation of alpha-synuclein and also enhance its clearance from cells by accelerating autophagy.
Lab website: http://blogs.helsinki.fi/prepinneuro/
“Special Seminar: Prolyl oligopeptidase (PREP) – a novel regulator for PP2A”Adjunct Prof. Timo Myöhänen, Drug Research Program, University of Helsinki
Host: Jukka Westermarck
Timo Myöhänen got his PhD (Pharmacology) in 2008 at University of Kuopio, and thereafter had post-doctoral visits in University of Antwerp (Belgium) and Georgetown University (Washington DC, USA) in 2010 and 2012. Dr. Myöhänen established his research group into Division of Pharmacology and Pharmacotherapy in University of Helsinki in 2011, got docentship in pharmacology in 2012 and is currently holding an Academy of Finland Research Fellow position. His research has focused on impact of a serine protease, prolyl oligopeptidase (PREP) and its pharmacological inhibition, on aggregation and toxicity of alpha-synuclein, a possible key player in cellular toxicity on Parkinson’s disease. Recent studies of Myöhänen lab have shown that PREP inhibitors can reduce the aggregation of alpha-synuclein and also enhance its clearance from cells by accelerating autophagy.
Lab website: http://blogs.helsinki.fi/prepinneuro/
#November
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. Robert Viger, Laval University, Quebec, Canada
“FoS: Understanding gonadal development and function: what we can learn from transcription studies”Prof. Robert Viger, Laval University, Quebec, Canada
Hosts: Nafis Rahman and Jorma Toppari
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Anniina Rintala, University of Turku
Host: Jaana Vuopio
“MIKRO: Gut microbes in the prevention and onset of metabolic disorders”Anniina Rintala, University of Turku
Host: Jaana Vuopio
PET centre seminar room, Kiinamyllynkatu 4-8, Turku
Florian Freudenberg, Translational Psychiatry Laboratory, Department of Psychiatry, Frankfurt University Hospital
Host: Michael Courtney
“Special Seminar: Targeted disruption of NOS-I PDZ interactions using viral gene transfer: Implications for psychiatric disorders”Florian Freudenberg, Translational Psychiatry Laboratory, Department of Psychiatry, Frankfurt University Hospital
Host: Michael Courtney
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. Duane A. Compton, Geisel School of Medicine at Dartmouth, Hanover, USA
“FoS: Causes and consequences of chromosomal instability in cancer”Prof. Duane A. Compton, Geisel School of Medicine at Dartmouth, Hanover, USA
Host: Sofia Pruikkonen
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. Andrew Cant, Institute of Cellular Medicine, University of Newcastle, UK
“FoS: Primary immunodeficiency: New understandings and new treatments”Prof. Andrew Cant, Institute of Cellular Medicine, University of Newcastle, UK
Host: Ville Peltola
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
MIKRO Seminars of Infection Biology and Infectious Diseases
Johanna Ivaska, University of Turku
Host: Raine Toivonen
“MIKRO Seminars: Imaging cancer cell invasion and the regulation of pluripotency”MIKRO Seminars of Infection Biology and Infectious Diseases
Johanna Ivaska, University of Turku
Host: Raine Toivonen
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
MIKRO Seminars of Infection Biology and Infectious Diseases
Ausra Domanska, University of Helsinki
Host: Petri Susi
MIKRO Seminars of Infection Biology and Infectious Diseases
Ausra Domanska, University of Helsinki
Host: Petri Susi
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. Mihai Netea, Faculty of Medical Sciences, Radboud University, Nijmegen, Netherlands
“FoS: Trained immunity: adaptation and memory in innate immune responses”Prof. Mihai Netea, Faculty of Medical Sciences, Radboud University, Nijmegen, Netherlands:
Host: Riitta Lahesmaa ( rilahes@utu.fi )
SmartBIO Annual Meeting will be arranged on Monday November 6th 2017 in Kankaisten Linna (Kankaistentie 57, 21250 Masku). SmartBIO is one of the seven BioCity Turku Research Programmes for the years 2016-2020. In this one-day meeting the scientific program (all in English) includes two invited lecturers from industry partners and fifteen-minute talks from SmatBIO team members.
The registration is now open until Oct 29th https://link.webropolsurveys.com/S/6116624FED0228CAYou can also find the registration from the SmartBIO web pages, together with the tentative program and more detailed information.
http://smartbio.fi/registration-smartbio-annual-meeting-2017-open
If you have any questions regarding the meeting please don’t hesitate to contact Maija Lespinasse (miholm@utu.fi).
SmartBIO Annual Meeting will be arranged on Monday November 6th 2017 in Kankaisten Linna (Kankaistentie 57, 21250 Masku). SmartBIO is one of the seven BioCity Turku Research Programmes for the years 2016-2020. In this one-day meeting the scientific program (all in English) includes two invited lecturers from industry partners and fifteen-minute talks from SmatBIO team members.
The registration is now open until Oct 29th https://link.webropolsurveys.com/S/6116624FED0228CAYou can also find the registration from the SmartBIO web pages, together with the tentative program and more detailed information.
http://smartbio.fi/registration-smartbio-annual-meeting-2017-open
If you have any questions regarding the meeting please don’t hesitate to contact Maija Lespinasse (miholm@utu.fi).
Ministeri auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Patrick Lewis, Reading School of Pharmacy, Reading, United Kingdom
Host: Eleanor Coffey
“Special Seminar: LRRK2 and macroautophagy – reading between the hieroglyphs”Patrick Lewis, Reading School of Pharmacy, Reading, United Kingdom
Host: Eleanor Coffey
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. Michael Hottiger, Department of Molecular Mechanisms of Disease, University of Zürich, Zürich, Switzerland
“FoS: Uncovering the functional role of protein ADP-ribosylation on the proteome-wide level”Prof. Michael Hottiger, Department of Molecular Mechanisms of Disease, University of Zürich, Zürich, Switzerland:
Host: Arto Pulliainen
The Hottiger-laboratory studies molecular regulatory mechanisms of inflammation, with special focus on the role of post-translation modifications in inflammatory signaling. They have contributed to the identification of protein ADP-ribosylation as a crucial process in the cellular response to detrimental stimuli, be it through genotoxicity, oxidative or metabolic stress, or excessive inflammation. Their current work focuses on the following questions: (i) Are ADP-ribosylation patterns cell-type specific or stimulus-specific, i.e. are there specific patterns that are associated with specific cell-physiological conditions? (ii) What are the modifiers (writer, binders, erasers) involved in those patterns? How can we specifically interfere with their activity to modulate the patterns? (iii) What are the regulatory mechanisms in ADP-ribosylation? How is the type and quantity of ADP-ribosylation patterns regulated? (iv) What are the downstream events of ADP-ribosylation, i.e. how does ADP-ribosylation alter the function of specific proteins and what is the effect on cell physiology? Most recently, the Hottiger-laboratory has studied the patterns of ADP-ribosylation using new systems biology approaches such as ADP-ribose specific high-resolution and quantitative mass spectrometry.
Website: http://www.dmmd.uzh.ch/en/research/hottiger.html
Selected publications:
Bisceglie L, Bartolomei G and Hottiger MO (2017) ADP-ribose-specific chromatin-affinity purification for investigating genome-wide or locus-specific chromatin ADP-ribosylation. Nature Protocols Sep;12(9):1951-1961.
Bilan V, Selevsek N, Kistemaker HAV, Abplanalp J, Feurer R, Filippov DV and Hottiger MO (2017) New quantitative mass spectrometry approaches reveal different ADP-ribosylation phases dependent on the levels of oxidative stress. Molecular & Cellular Proteomics May;16(5):949-958.
Bilan V, Leutert M, Nanni P, Panse C, Hottiger MO (2017) Combining Higher-Energy collision dissociation and electron-transfer/higher energy collision dissociation fragmentation in a product-dependent manner confidently assigns proteomewide ADP-ribose acceptor Sites. Analytical Chemistry Feb 7;89(3):1523-1530.
Martello R, Leutert M, Jungmichel S, Bilan V, Larsen SC, Young C, Hottiger MO and Nielsen ML (2016) Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue. Nature Communications Sep 30;7:12917. doi:
Leutert M, Pedrioli DML and Hottiger MO (2016) Identification of PARP-specific ADP-ribosylation targets reveals a regulatory function for ADP-ribosylation in transcription elongation. Molecular Cell Jul 21;63(2):181-183.
Hottiger MO (2015) SnapShot: ADP-ribosylation signaling. Molecular Cell Jun 18;58(6):1134-1134.e1.
#October
Wikgren lecture room, BioCity 1st floor, Tykistökatu 6, Turku
Associate Professor Sven Nelander, Uppsala University, Uppsala, Sweden
Receptor Program Seminar
Host: Jukka Westermarck (jukwes(at)utu.fi)
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Sven Nelander is an Associate Professor at the Department of Immunology, Genetics and Pathology and Science for Life Laboratory at Uppsala University. His research group focuses on integrated approaches to cancer intervention, combining computational and experimental methods. A key diagnostic focus is GBM. Sven Nelander received his PhD in 2005 at the University of Gothenburg and trained as a postdoc at Memorial Sloan Kettering Cancer Center, NY (Sander lab). He joined Uppsala University in 2012.
Associate Professor Sven Nelander, Uppsala University, Uppsala, Sweden
Receptor Program Seminar
Host: Jukka Westermarck (jukwes(at)utu.fi)
****
Sven Nelander is an Associate Professor at the Department of Immunology, Genetics and Pathology and Science for Life Laboratory at Uppsala University. His research group focuses on integrated approaches to cancer intervention, combining computational and experimental methods. A key diagnostic focus is GBM. Sven Nelander received his PhD in 2005 at the University of Gothenburg and trained as a postdoc at Memorial Sloan Kettering Cancer Center, NY (Sander lab). He joined Uppsala University in 2012.
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. Mads Gyrd-Hansen, Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK:
Host: Annika Meinander (annika.meinander(at)abo.fi) (Receptor)
**************
The Gyrd-Hansen laboratory studies molecular mechanisms governing pro-inflammatory signalling during innate immune responses. Through this, they aim to understand the molecular mechanisms that on one hand protect against pathogens, but that also contribute to chronic inflammation, tumor development and cancer progression. A central focus of the lab is to elucidate the role and regulation of non-degradative ubiquitin modifications in these processes. Ultimately, they aim to identify ubiquitin-handling factors that can be targeted to modulate inflammation and antagonize cancer. Professor Gyrd-Hansen’s recent work has focused on the role of Met1-linked ubiquitin chains (also known as linear ubiquitin chains) in inflammatory signaling. These chains are generated by the Linear UBiquitin Assembly Complex (LUBAC), which is a key component of inflammatory signaling pathways, including those activated downstream of the cytoplasmic PRRs NOD1 and NOD2 that serve as sensors for intracellular bacteria. They have uncovered and characterised several factors that regulate the function of LUBAC in signaling. Future work in the group will focus on elucidating the function, regulation and interplay of individual ubiquitin chain types (of which there are at least eight) in the cellular response to infection.
Website: http://www.ludwig.ox.ac.uk/mads-gyrd-hansen
Selected publications:
Gyrd-Hansen M. All roads lead to ubiquitin. Cell Death Differ. 2017 Jul;24(7):1135-1136. doi: 10.1038/cdd.2017.93.
Elliott PR, Leske D, Hrdinka M, Bagola K, Fiil BK, McLaughlin SH, Wagstaff J, Volkmar N, Christianson JC, Kessler BM, Freund SM, Komander D, Gyrd-Hansen M. SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling. Mol Cell. 2016 Sep 15;63(6):990-1005. doi: 10.1016/j.molcel.2016.08.001.
Hrdinka M, Fiil BK, Zucca M, Leske D, Bagola K, Yabal M, Elliott PR, Damgaard RB, Komander D, Jost PJ, Gyrd-Hansen M. CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling. Cell Rep. 2016 Mar 29;14(12):2846-58. doi: 10.1016/j.celrep.2016.02.062.
Fiil BK, Gyrd-Hansen M. Met1-linked ubiquitination in immune signalling. FEBS J. 2014 Oct;281(19):4337-50. doi: 10.1111/febs.12944.
Damgaard RB, Fiil BK, Speckmann C, Yabal M, zur Stadt U, Bekker-Jensen S, Jost PJ, Ehl S, Mailand N, Gyrd-Hansen M. Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling. EMBO Mol Med. 2013 Aug;5(8):1278-95. doi: 10.1002/emmm.201303090.
Fiil BK, Damgaard RB, Wagner SA, Keusekotten K, Fritsch M, Bekker-Jensen S, Mailand N, Choudhary C, Komander D, Gyrd-Hansen M. OTULIN restricts Met1-linked ubiquitination to control innate immune signaling. Mol Cell. 2013 Jun
27;50(6):818-830. doi: 10.1016/j.molcel.2013.06.004.
Damgaard RB, Nachbur U, Yabal M, Wong WW, Fiil BK, Kastirr M, Rieser E, Rickard JA, Bankovacki A, Peschel C, Ruland J, Bekker-Jensen S, Mailand N, Kaufmann T, Strasser A, Walczak H, Silke J, Jost PJ, Gyrd-Hansen M. The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. Mol Cell. 2012 Jun 29;46(6):746-58. doi: 10.1016/j.molcel.2012.04.014.
“FoS: Ubiquitin signalling in inflammation”Prof. Mads Gyrd-Hansen, Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK:
Host: Annika Meinander (annika.meinander(at)abo.fi) (Receptor)
**************
The Gyrd-Hansen laboratory studies molecular mechanisms governing pro-inflammatory signalling during innate immune responses. Through this, they aim to understand the molecular mechanisms that on one hand protect against pathogens, but that also contribute to chronic inflammation, tumor development and cancer progression. A central focus of the lab is to elucidate the role and regulation of non-degradative ubiquitin modifications in these processes. Ultimately, they aim to identify ubiquitin-handling factors that can be targeted to modulate inflammation and antagonize cancer. Professor Gyrd-Hansen’s recent work has focused on the role of Met1-linked ubiquitin chains (also known as linear ubiquitin chains) in inflammatory signaling. These chains are generated by the Linear UBiquitin Assembly Complex (LUBAC), which is a key component of inflammatory signaling pathways, including those activated downstream of the cytoplasmic PRRs NOD1 and NOD2 that serve as sensors for intracellular bacteria. They have uncovered and characterised several factors that regulate the function of LUBAC in signaling. Future work in the group will focus on elucidating the function, regulation and interplay of individual ubiquitin chain types (of which there are at least eight) in the cellular response to infection.
Website: http://www.ludwig.ox.ac.uk/mads-gyrd-hansen
Selected publications:
Gyrd-Hansen M. All roads lead to ubiquitin. Cell Death Differ. 2017 Jul;24(7):1135-1136. doi: 10.1038/cdd.2017.93.
Elliott PR, Leske D, Hrdinka M, Bagola K, Fiil BK, McLaughlin SH, Wagstaff J, Volkmar N, Christianson JC, Kessler BM, Freund SM, Komander D, Gyrd-Hansen M. SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling. Mol Cell. 2016 Sep 15;63(6):990-1005. doi: 10.1016/j.molcel.2016.08.001.
Hrdinka M, Fiil BK, Zucca M, Leske D, Bagola K, Yabal M, Elliott PR, Damgaard RB, Komander D, Jost PJ, Gyrd-Hansen M. CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling. Cell Rep. 2016 Mar 29;14(12):2846-58. doi: 10.1016/j.celrep.2016.02.062.
Fiil BK, Gyrd-Hansen M. Met1-linked ubiquitination in immune signalling. FEBS J. 2014 Oct;281(19):4337-50. doi: 10.1111/febs.12944.
Damgaard RB, Fiil BK, Speckmann C, Yabal M, zur Stadt U, Bekker-Jensen S, Jost PJ, Ehl S, Mailand N, Gyrd-Hansen M. Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling. EMBO Mol Med. 2013 Aug;5(8):1278-95. doi: 10.1002/emmm.201303090.
Fiil BK, Damgaard RB, Wagner SA, Keusekotten K, Fritsch M, Bekker-Jensen S, Mailand N, Choudhary C, Komander D, Gyrd-Hansen M. OTULIN restricts Met1-linked ubiquitination to control innate immune signaling. Mol Cell. 2013 Jun
27;50(6):818-830. doi: 10.1016/j.molcel.2013.06.004.
Damgaard RB, Nachbur U, Yabal M, Wong WW, Fiil BK, Kastirr M, Rieser E, Rickard JA, Bankovacki A, Peschel C, Ruland J, Bekker-Jensen S, Mailand N, Kaufmann T, Strasser A, Walczak H, Silke J, Jost PJ, Gyrd-Hansen M. The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. Mol Cell. 2012 Jun 29;46(6):746-58. doi: 10.1016/j.molcel.2012.04.014.
Ministeri auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
For symposium program, click here.
Register latest Oct 22nd at: https://link.webropolsurveys.com/S/C1C0722937CB171E
“SyMMyS Symposium: New insights into Type 1 diabetes and regulation of immune responses”For symposium program, click here.
Register latest Oct 22nd at: https://link.webropolsurveys.com/S/C1C0722937CB171E
Dentalia Auditorium (Arje Scheinin), 2nd floor, Lemminkäisenkatu 2, Turku
Prof. Ville Kaila, Department of Chemistry, Technical University of Munich, Germany
“FoS: Exploring molecular mechanisms in biological energy conversion”Prof. Ville Kaila, Department of Chemistry, Technical University of Munich, Germany
Host: Paula Mulo
Description of research:
The research of Prof. Ville Kaila is focused on enzymatic and biomimetic catalysts for energy conversion. These processes are studied in respiratory and photosynthetic enzymes, but also in non-biological systems such as water-splitting molecular catalysts and molecular capsules. Prof. Kaila applies and develops powerful computational methodology ranging from ab initio quantum chemical techniques, hybrid quantum mechanics/classical mechanics (QM/MM) and subsystems methods, to large-scale classical molecular dynamics simulations, free-energy and continuum approaches.
Prof. Kaila will describe his recent work on the respiratory Complex I, and he will discuss how combination of experiments and multi-scale molecular simulations can provide a powerful methodology to obtain a molecular-level understanding of the structure, energetics, and dynamics of energy-capturing proteins, and how such methods can further be employed to engineer and design new proteins with desired target functions.
Selected publications:
Sharma V, Belevich G, Gamiz-Hernandez AP, Róg T, Vattulainen I, Wikström M, Hummer G, Kaila VRI (2015) Redox-Induced Activation of the Proton Pump in the Respiratory Complex I Proc. Natl. Acad. Sci. USA 112:11571-11576.
Kmita K, Wirth C, Warnau J, Guerrero-Castillo S, Hunte C, Hummer G, Kaila VRI, Zwicker K, Brandt U, Zickermann V. (2015) Accessory NUMM (NDUFS6) subunit harbors a Zn-binding site and is essential for biogenesis of mitochondrial complex I. Proc. Natl. Acad. Sci. USA 112:5685-5690.
Boczek EE, Reefschläger LG, Dehling M, Struller T, Häusler E, Seidl A, Kaila VRI, Buchner J (2014) Conformational processing of oncogenic v-Src kinase by Hsp90. Proc. Natl. Acad. Sci. USA 112: E3189-3198.
Wikström M, Sharma V, Kaila VRI, Hosler J, Hummer G (2015) New perspectives on proton pumping in cellular respiration. Chem. Rev. 115, 2196-2221.
Kaila VRI , Schotte F, Hyun S-C, Hummer G, Anfinrud PA (2014) Reconciling contradictions in time-resolved x-ray structures of early intermediates in the photocycle of photoactive yellow protein Nature Chem 6:258-259.
Kaila VRI , Wikström M, Hummer G (2014) Electrostatics, Hydration, and Proton Transfer Dynamics in the Membrane Domain of Respiratory Complex I. Proc Natl Acad Sci USA 111, 6988-6993.
Schotte F, Hyun S-C, Kaila VRI, Kamikubo H, Dashdorja N, Henry E, Graber T, Henning R, Wulff M, Hummer G, Kataoka M, Anfinruda PA (2012) Picosecond Photobiology: Watching a Signaling Protein Function in Real Time via Time-resolved Laue Crystallography. Proc Natl Acad Sci USA 109, 19256-19261.
PharmaCity Auditorium, Itäinen Pitkäkatu 4B, Turku
Robert Lyle, Oslo University Hospital and University of Oslo, Norway
Host: Riikka Lund
“Long-term prenatal exposure to paracetamol is associated with DNA methylation differences in children diagnosed with ADHD”Robert Lyle, Oslo University Hospital and University of Oslo, Norway
Host: Riikka Lund
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Päivi Saavalainen, University of Helsinki
Host: Jorma Ilonen
Päivi Saavalainen, University of Helsinki
Host: Jorma Ilonen
Auditorium Beta, ICT-building, Joukahaisenkatu 3-5, Turku
Program
10.00 Coffee
10.15 Professor Noel Morgan, University of Exeter Medical School, UK: “Type 1 diabetes; evidence for disease heterogeneity”
11.00 Dr Sarah Richardson, University of Exeter Medical School, UK: “Is Type 1 Diabetes ‘Going Viral’?”
11.45 Dr. Mark Russell, Islet Biology Exeter, UK: “JAK/STAT Signalling in the Pathogenesis of Type 1 Diabetes”
Organised by:
The Academy of Finland Centre of Excellence in Molecular Systems Immunology and Physiology
Turku Centre for LIFESPAN Research
“MINISYMPOSIUM: Molecular Mechanisms of Type 1 Diabetes”
Program
10.00 Coffee
10.15 Professor Noel Morgan, University of Exeter Medical School, UK: “Type 1 diabetes; evidence for disease heterogeneity”
11.00 Dr Sarah Richardson, University of Exeter Medical School, UK: “Is Type 1 Diabetes ‘Going Viral’?”
11.45 Dr. Mark Russell, Islet Biology Exeter, UK: “JAK/STAT Signalling in the Pathogenesis of Type 1 Diabetes”
Organised by:
The Academy of Finland Centre of Excellence in Molecular Systems Immunology and Physiology
Turku Centre for LIFESPAN Research
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. Antti Poso, University of Eastern Finland, School of Pharmacy; Distinguished Guest Professor at the University of Tübingen in Germany
Host: Outi Salo-Ahen (outi.salo-ahen(at)abo.fi)
Prof. Antti Poso’s main research interest has been computer-aided drug design and early hit/lead identification and optimization. He did his post-doctoral research as a Humboldt-fellow in Düsseldorf with Prof. H.-D. Höltje (1997-1998) and after returning to Finland he started his own molecular modeling group. One of his first major research topics was to identify and optimize sirtuin inhibitors, especially against Sirt2. His group has also contributed substantially to the design of new compounds targeting different proteins of the endogenous cannabinoid system, such as CB1 and CB2 receptors as well as MAGL and FAAH enzymes. In recent years, his interest has shifted mainly to anti-cancer and anti-infective drug design, although he is also active in projects aiming to find new therapies to age-related macular degeneration. Besides his position at the University of Eastern Finland, he has also worked at FIMM (Helsinki) with Prof. Kallioniemi and since 2012 as a Guest Professor at the University of Tübingen (Germany) with professors Zender and Laufer.
About the seminar topic:
The seminar talk will discuss three separate projects in anti-cancer drug discovery. The introduction will give a brief overview of the methods used in Kuopio and Tübingen. The first case study is about a ribosomal drug targeting project and how early computational work is mandatory for a successful druggable target identification. The other two projects (targeting a kinase and DNA replication proteins) are both currently in the late lead-optimization phase.
“From drug design to target selection: developing new anti-cancer and CNS-targeting compounds”
Prof. Antti Poso, University of Eastern Finland, School of Pharmacy; Distinguished Guest Professor at the University of Tübingen in Germany
Host: Outi Salo-Ahen (outi.salo-ahen(at)abo.fi)
Prof. Antti Poso’s main research interest has been computer-aided drug design and early hit/lead identification and optimization. He did his post-doctoral research as a Humboldt-fellow in Düsseldorf with Prof. H.-D. Höltje (1997-1998) and after returning to Finland he started his own molecular modeling group. One of his first major research topics was to identify and optimize sirtuin inhibitors, especially against Sirt2. His group has also contributed substantially to the design of new compounds targeting different proteins of the endogenous cannabinoid system, such as CB1 and CB2 receptors as well as MAGL and FAAH enzymes. In recent years, his interest has shifted mainly to anti-cancer and anti-infective drug design, although he is also active in projects aiming to find new therapies to age-related macular degeneration. Besides his position at the University of Eastern Finland, he has also worked at FIMM (Helsinki) with Prof. Kallioniemi and since 2012 as a Guest Professor at the University of Tübingen (Germany) with professors Zender and Laufer.
About the seminar topic:
The seminar talk will discuss three separate projects in anti-cancer drug discovery. The introduction will give a brief overview of the methods used in Kuopio and Tübingen. The first case study is about a ribosomal drug targeting project and how early computational work is mandatory for a successful druggable target identification. The other two projects (targeting a kinase and DNA replication proteins) are both currently in the late lead-optimization phase.
Dentalia Auditorium (Arje Scheinin), 2nd floor, Lemminkäisenkatu 2, Turku
Prof. W. Brent Derry, The Hospital for Sick Children and Department of Molecular Genetics, University of Toronto
Host: Annika Meinander (ÅAU Cell Biology and Receptor Programme)
The broad goal of Derry’s research is to understand how genes that are mutated in various diseases function in vivo. He uses the powerful genetics and functional genomics tools of the model organism Caenorhabditis elegans to understand how tumour suppressors and oncogenes control cell survival, genome stability and organism development. He is particularly interested in how cells communicate with one another to sculpt organs and make life or death decisions when challenged with stresses, such as chemotherapy and radiation. Derry also has a robust research program that is focused on understanding the mechanistic basis of the human neurovascular disease cerebral cavernous malformations (CCM). He is collaborating with an international team of scientists and clinicians to discover drugs that can be used to prevent the onset of CCM in humans.
Selected publications:
Pal, S., Lant, B., Yu, B., Tian, R., Tong, J., Krieger, J.R., Moran, M.F., Gingras, A.C., & Derry, W. B. CCM-3 Promotes C. elegans germline development by regulating vesicle trafficking cytokinesis and polarity. (2017) Current Biology. 27(6): 868-876.
Eroglu, M. & Derry, W.B. (2016) Your neighbours matter – non-autonomous control of apoptosis in development and disease. Cell Death and Differentiation. 23(7): 1110-1118.
Mateo, A.R, Kessler, Z., Jolliffe, A.K., McGovern, O., Yu, B., Nicolucci, A., Yanowitz, J.L. & Derry, W.B. (2016) The p53-like protein CEP-1 is required for meiotic fidelity in C. elegans. Current Biology. 26(9): 1148-1158.
Lant B, Yu B, Goudreault M, Holmyard D, Knight JD, Xu P, Zhao L, Chin K, Wallace E, Zhen M, Gingras AC, Derry WB. (2015) CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling. Nature Communications. 6: 6449.
Baruah, A., Chang, H., Hall, M., Yuan, J., Gordon, S., Johnson, E., Shtessel, L.L., Yee, C., Hekimi, S., Derry, W.B., & Lee, S.S. (2014). CEP1, the Caenorhabditis elegans p53 homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutants. PLoS Genetics. 10(2): e1004097.
Perrin, A.J., Gunda, M., Yu, B., Yen, K., Ito, S., Forster, S., Young, J., Tissenbaum, H.A. & Derry, W.B. (2013). Noncanonical control of C. elegans germline apoptosis by the insulin/IGF-1 and Ras/MAPK signaling pathways. Cell Death and Differentiation. 20(1): 97-107.
Ross, A.J., Li, M., Yu, B., Gao, M.X. & Derry, W.B. (2011). The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans. Cell Death and Differentiation. 18(7): 1140-1149.
Ito, S., Greiss, S., Gartner, A. & Derry, W.B. (2010). Cell-nonautonomous regulation of C. elegans germ cell death by kri-1. Current Biology. 20(4): 333-338.
Gao, X. Liao, E., Yu, B., Wang, Y., Zhen, M. & Derry, W.B. (2008). The SCFFSN-1 ubiquitin ligase controls CEP-1/p53-dependent apoptosis in Caenorhabditis elegans. Cell Death and Differentiation. 15(6): 1054-1062.
Quevedo, C., Kaplan, D.R. & Derry, W.B. (2007). AKT-1 regulates DNA-damage induced germline apoptosis in C. elegans. Current Biology. 17(3): 286-292.
“Regulation of oncogenic Ras by alternative polyadenylation and microRNAs”Prof. W. Brent Derry, The Hospital for Sick Children and Department of Molecular Genetics, University of Toronto
Host: Annika Meinander (ÅAU Cell Biology and Receptor Programme)
The broad goal of Derry’s research is to understand how genes that are mutated in various diseases function in vivo. He uses the powerful genetics and functional genomics tools of the model organism Caenorhabditis elegans to understand how tumour suppressors and oncogenes control cell survival, genome stability and organism development. He is particularly interested in how cells communicate with one another to sculpt organs and make life or death decisions when challenged with stresses, such as chemotherapy and radiation. Derry also has a robust research program that is focused on understanding the mechanistic basis of the human neurovascular disease cerebral cavernous malformations (CCM). He is collaborating with an international team of scientists and clinicians to discover drugs that can be used to prevent the onset of CCM in humans.
Selected publications:
Pal, S., Lant, B., Yu, B., Tian, R., Tong, J., Krieger, J.R., Moran, M.F., Gingras, A.C., & Derry, W. B. CCM-3 Promotes C. elegans germline development by regulating vesicle trafficking cytokinesis and polarity. (2017) Current Biology. 27(6): 868-876.
Eroglu, M. & Derry, W.B. (2016) Your neighbours matter – non-autonomous control of apoptosis in development and disease. Cell Death and Differentiation. 23(7): 1110-1118.
Mateo, A.R, Kessler, Z., Jolliffe, A.K., McGovern, O., Yu, B., Nicolucci, A., Yanowitz, J.L. & Derry, W.B. (2016) The p53-like protein CEP-1 is required for meiotic fidelity in C. elegans. Current Biology. 26(9): 1148-1158.
Lant B, Yu B, Goudreault M, Holmyard D, Knight JD, Xu P, Zhao L, Chin K, Wallace E, Zhen M, Gingras AC, Derry WB. (2015) CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling. Nature Communications. 6: 6449.
Baruah, A., Chang, H., Hall, M., Yuan, J., Gordon, S., Johnson, E., Shtessel, L.L., Yee, C., Hekimi, S., Derry, W.B., & Lee, S.S. (2014). CEP1, the Caenorhabditis elegans p53 homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutants. PLoS Genetics. 10(2): e1004097.
Perrin, A.J., Gunda, M., Yu, B., Yen, K., Ito, S., Forster, S., Young, J., Tissenbaum, H.A. & Derry, W.B. (2013). Noncanonical control of C. elegans germline apoptosis by the insulin/IGF-1 and Ras/MAPK signaling pathways. Cell Death and Differentiation. 20(1): 97-107.
Ross, A.J., Li, M., Yu, B., Gao, M.X. & Derry, W.B. (2011). The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans. Cell Death and Differentiation. 18(7): 1140-1149.
Ito, S., Greiss, S., Gartner, A. & Derry, W.B. (2010). Cell-nonautonomous regulation of C. elegans germ cell death by kri-1. Current Biology. 20(4): 333-338.
Gao, X. Liao, E., Yu, B., Wang, Y., Zhen, M. & Derry, W.B. (2008). The SCFFSN-1 ubiquitin ligase controls CEP-1/p53-dependent apoptosis in Caenorhabditis elegans. Cell Death and Differentiation. 15(6): 1054-1062.
Quevedo, C., Kaplan, D.R. & Derry, W.B. (2007). AKT-1 regulates DNA-damage induced germline apoptosis in C. elegans. Current Biology. 17(3): 286-292.
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Akira Takeda, University of Turku
Host: Raine Toivonen
“Thymocytes in Lyve1-CRE/S1pr1f/f mice accumulate in the thymus due to cell-intrinsic loss of sphingosine-1-phosphate receptor expression”Akira Takeda, University of Turku
Host: Raine Toivonen
#September
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Simo Nikkari, Center for Military Medicine
Host: Alex-Mikael Barkoff
“From GHSA assessments to the JEE Alliance”
Simo Nikkari, Center for Military Medicine
Host: Alex-Mikael Barkoff
T32, Dentalia 2nd floor, Lemminkäisenkatu 2, Turku
Paolo Pesaresi and Carlotta Peracchio, Università degli studi di Milano
“GUN1, a Jack-Of-All-Trades in Chloroplast Protein Homeostasis and Signaling”Paolo Pesaresi and Carlotta Peracchio, Università degli studi di Milano
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Dr. Marc Therrien, Université de Montréal, Montreal, Quebec, Canada
“Structural characterization and pharmacological targeting of dimerization-induced RAF activation”Dr. Marc Therrien, Université de Montréal, Montreal, Quebec, Canada
Host: Daniel Abankwa
Mauno Conferene Center, Presidentti auditorium, BioCity, Tykistökatu 6, Turku
Turku Cancer Research Society is pleased to announce a daylong seminar on drug discovery and development entitled ‘ACADEMIC CANCER DRUG DEVELOPMENT: Challenges and successes’.
This seminar with distinguished speakers from Finland, Europe and overseas will take place on Monday September 25, 2017 in Congress Centre Mauno, Turku. For more details and registration please visit http://cancerresearch.utu.fi.
“ACADEMIC CANCER DRUG DEVELOPMENT: Challenges and successes”Turku Cancer Research Society is pleased to announce a daylong seminar on drug discovery and development entitled ‘ACADEMIC CANCER DRUG DEVELOPMENT: Challenges and successes’.
This seminar with distinguished speakers from Finland, Europe and overseas will take place on Monday September 25, 2017 in Congress Centre Mauno, Turku. For more details and registration please visit http://cancerresearch.utu.fi.
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Prof. Frank Claessens, Laboratory of Molecular Endocrinology, Leuven, Belgium
Host: Matti Poutanen
“Symmetry and allostery in the androgen receptor”Prof. Frank Claessens, Laboratory of Molecular Endocrinology, Leuven, Belgium
Host: Matti Poutanen
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Subhash K. Tripathi, University of Turku
“STAT3 regulated Transcription During Early Human T helper 17 Lineage specification”Subhash K. Tripathi, University of Turku
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Satu Pekkala, University of Jyväskylä
Host: Eveliina Munukka
“The bugs that live with us and metabolic disorders – from associations to mechanisms”Satu Pekkala, University of Jyväskylä
Host: Eveliina Munukka
Dentalia Auditorium (Arje Scheinin), 2nd floor, Lemminkäisenkatu 2, Turku
Dr. Eugene V Koonin, National Center for Biotechnology, Information National Library of Medicine, NIH, Bethesda, USA
“Mobile genetic elements and evolution of CRISPR-Cas systems: all the way there and back”Dr. Eugene V Koonin, National Center for Biotechnology Information, National Library of Medicine, NIH, Bethesda, USA
Host: Pere Puigbo (pepuav(at)utu.fi)
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Professor James Golden, University California, San Diego:
”Broad-Host-Range Genetic Tools for Cyanobacteria and Heterologous Expression of Natural Products”
Professor Susan Golden, Distinguished Professor Director, University California, San Diego:
”A Day in the Life of a Cyanobacterium: integrating temporal and environmental information”
Professor James Golden, University California, San Diego:
”Broad-Host-Range Genetic Tools for Cyanobacteria and Heterologous Expression of Natural Products”
Professor Susan Golden, Distinguished Professor Director, University California, San Diego:
”A Day in the Life of a Cyanobacterium: integrating temporal and environmental information”
#August
Auditorium Beta, ICT-building, Joukahaisenkatu 3-5, Turku
Professor Pirjo Nuutila, University of Turku
Chair: Jorma Toppari
Coffee will be served at 12.00
Seminar 12.15-13.00 is followed by discussion
“Secrets to a good grant application for the Academy of Finland”
Professor Pirjo Nuutila, University of Turku
Chair: Jorma Toppari
Coffee will be served at 12.00
Seminar 12.15-13.00 is followed by discussion
Dentalia, Dent 1, Lemminkäisenkatu 2, Turku
The newly formed Turku Metabolomics facility is pleased to announce a seminar to celebrate its opening.
9:30 Welcome and coffee
10:00 Matej Orešič (UTU) – Metabolomics in biomedical research: platforms, challenges, opportunities
10:10 Alex Dickens (UTU) – Biomarkers/Turku core facility
10:30 Jari Sinkkonen (UTU) – Tissue NMR for metabolomics at the NMR Instrument Centre
10:45 Mika Scheinin (UTU/Turku University Hospital) – Pharmacokinetics and verification of drug exposure
11:00 Dawei Geng (Örebro University, Sweden) – Metabolomics at Örebro University and collaboration with Turku Metabolomics facility
11:20 Linda Ahonen (Steno Diabetes Center Copenhagen, Denmark) – Lipidomics with automatized QC – case study: NIST ring trial
11:40 Kati Hanhineva (University of Eastern Finland) – Untargeted metabolomics for nutrition and food research
12:00 Reception and adjourn
The newly formed Turku Metabolomics facility is pleased to announce a seminar to celebrate its opening.
9:30 Welcome and coffee
10:00 Matej Orešič (UTU) – Metabolomics in biomedical research: platforms, challenges, opportunities
10:10 Alex Dickens (UTU) – Biomarkers/Turku core facility
10:30 Jari Sinkkonen (UTU) – Tissue NMR for metabolomics at the NMR Instrument Centre
10:45 Mika Scheinin (UTU/Turku University Hospital) – Pharmacokinetics and verification of drug exposure
11:00 Dawei Geng (Örebro University, Sweden) – Metabolomics at Örebro University and collaboration with Turku Metabolomics facility
11:20 Linda Ahonen (Steno Diabetes Center Copenhagen, Denmark) – Lipidomics with automatized QC – case study: NIST ring trial
11:40 Kati Hanhineva (University of Eastern Finland) – Untargeted metabolomics for nutrition and food research
12:00 Reception and adjourn
#June
Turku Centre for Biotechnology, 5th floor seminar room, BioCity B-staircase, Tykistökatu 6, Turku
Dr. Lorna Young, Laboratory of Prof. Harry Higgs, Geisel School of Medicine, Dartmouth College, USA
“Interplay between filopodia, focal adhesions and stress fibers”Medisiina, room C202, 2nd floor, Kiinamyllynkatu 10, Turku
Dr. Bert Dhondt, University of Ghent, Belgium
“Isolation of extracellular vesicles from biological fluids for uro-oncological biomarker studies”Host: Jyrki Heino (jyrki.heino(at)utu.fi)
Turku Centre for Biotechnology, 5th floor seminar room, BioCity B-staircase, Tykistökatu 6, Turku
Mario Pagano, University of Padova, Italy
“Targeting the tumor suppressor PP2A: a new paradigm for paving the way to panacea?”Host: Jukka Westermarck
PharmaCity Auditorium, Itäinen Pitkäkatu 4B, Turku
Maijaliisa Erkkola, Dep. of Food and Environmental Sciences, University of Helsinki
“Preschool as an arena for health promotion; LILLA- and DAGIS -studies”Host: Kirsi Laitinen ( kirsi.laitinen@utu.fi )
PharmaCity Auditorium, Itäinen Pitkäkatu 4B, Turku
Michael Brenan, Research Associate, 1CellBio
“1CellBio technology for single cell analysis and the future prospective of the single cell analysis”Host: Hongbo Zhang
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Dr. Jan Lammerding, Nancy E. and Peter C. Meinig School of Biomedical Engineering, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, USA
“Squish and squeeze – Nuclear rupture and mechanics in cell migration and muscle disease”Host: Pekka Taimen
#May
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Pirjo Merilahti University of Turku
“Receptor tropism and pathogenicity of human parechoviruses”Host: Sisko Tauriainen
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Dr. Vinagolu K. Rajasekhar, Senior Research Scientist, Memorial Sloan Kettering Cancer Center, New York, NY
“Alternative options for clinically relevant animal modeling of human cancers”Host: Johanna Tuomela (jomitu@utu.fi)
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Professor David F. Stern, Department of Pathology, Yale University, New Haven, USA
“Attacking and preventing treatment-selected resistance to cancer signaling drugs”Host: Klaus Elenius
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Thorsten Joeris, Lund University, Sweden
“Intestinal Antigen Presenting Cells in the regulation of mucosal CD8 T cell responses to epithelial derived antigen”Host: Raine Toivonen
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Juhani Aakko University of Turku
“Mining and modelling metaproteomics data”Host: Arno Hänninen
PharmaCity Auditorium, Itäinen Pitkäkatu 4B, Turku
Prof. Steven Pals, University of Amsterdam, The Netherlands
“Provoking homelessness as strategy to treat lymphoma”Host: Sirpa Jalkanen
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Professor Benjamin G. Neel, Laura and Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, USA
“New tricks for old protein tyrosine phosphatases (PTPs)”Host: Jukka Westermarck
Dentalia Auditorium (Arje Scheinin), 2nd floor, Lemminkäisenkatu 2, Turku
Teemu Smura University of Helsinki
“Zikavirus evolution”Host: Sisko Tauriainen
PharmaCity Auditorium, Itäinen Pitkäkatu 4B, Turku
Professor Pirkko Härkönen, University of Turku
“Fibroblast growth factor receptor pathways in growth regulation and as therapeutic targets in breast and prostate cancer”Host: Kirsi Laitinen
#April
PharmaCity Auditorium, Itäinen Pitkäkatu 4B, Turku
Professor Brian C. Freeman, Department of Cell & Developmental Biology, University of Illinois, Urbana, Illinois, USA
“Molecular chaperones regulate the chromatin landscape. Is it time to move?”Host: Lea Sistonen
PharmaCity Auditorium, Itäinen Pitkäkatu 4B, Turku
Professor Hongquan Zhang, Department of Anatomy, Histology and Embryology and Laboratory of Molecular Cell Biology and Tumor
“Integrin-interacting proteins Kindlins: biology and related diseases”Host: Jyrki Heino
Dent 2, Dentalia, Lemminkäisenkatu 2, Turku
Pirjo Merilahti, University of Turku
“Receptor tropism and pathogenicity of human parechoviruses”Host: Sisko Tauriainen
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Professor Dietrich Kabelitz, Department of Immunology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
“?? T-cells: An immune cell population at the cross-road of innate and adaptive immunity”Host: Jorma Määttä
#March
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Professor Henk Stunnenberg, Department of Molecular Biology, Radboud University, Nijmegen, The Netherlands
“Epigenomics uncovers dysregulated regulatory pathways”Host: Riitta Lahesmaa
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Academy professor Virpi Lummaa, University of Turku, Turku, Finland
“Births, deaths and natural selection in contemporary Finland”Host: Jyrki Heino
#February
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Professor Carl-Henrik Heldin, Ludwig Institute for Cancer Research, Science for Life Laboratory, Uppsala University, Uppsala, Sweden
“Signaling via receptors for TGF? – possible targets for tumor therapy”Host: Anna Knittle
#January
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Dr. Marco Fritzsche, MRC Human Immunology Unit, Weatherall Institute for Molecular Medicine, University of Oxford, Oxford, UK
“Cytoskeletal actin dynamics underpin immunological synapse formation”Host: Pieta Mattila
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Tero Ahola, University of Helsinki
“Discovering new antivirals agaisnt alphaviruses and other RNA viruses”Host: Petri Susi
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Professor Jussi Taipale, Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
“Systems biology of cancer”Host: Jukka Westermarck
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Professor Wouter de Laat, Hubrecht Institute, Utrecht, The Netherlands
“The use of 3C technologies to study the shape and function of the genome and enable new applications in DNA diagnostics”Host: Riitta Lahesmaa
#December
Pha3 seminar room, PharmaCity, Itäinen Pitkäkatu 4, Turku
Speaker: Dr. Julie Bouckaert, University of Lille, France
“Bacterial adhesion at the site of inflammation: a sugary liaison”Speaker: Dr. Julie Bouckaert, University of Lille, France
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. Birgit Lane, Institute of Medical Biology and Skin Research Institute of Singapore, Nanyang Technological University, Singapore
“Lessons from rare skin diseases”Host: Diana Toivola
Biology seminar room 215, Natura, 2nd floor, Turun yliopisto, natura, Turku, 20500
Dr. Thomas Lilley, Department of Biology, University of Turku & Bucknell University, Lewisburg, USA
“White-nose syndrome in bats”Host: Päivi Koskinen
PharmaCity Auditorium, Itäinen Pitkäkatu 4B, Turku
Registration (latest on Monday, 5 December)
“Scientific publishing – ethics, metrics and beyond”Registration (latest on Monday, 5 December)
Keidas, Medisiina 2nd floor, Kiinamyllynkatu 10, Turku
Programmme
Registration by 29.11. to contact-tcrs@lists.utu.fi
Please also indicate a possible special diet when registering.
“Cancer Immunology – from basic mechanisms to therapy”Programmme
Registration by 29.11. to contact-tcrs@lists.utu.fi
Please also indicate a possible special diet when registering.
Dentalia, Dent 3, Lemminkäisenkatu 2, Turku
Siri Tähtinen, University of Helsinki
“Oncolytic adenoviruses as enablers of efficient cancer immunotherapies”Host: Laura Kakkola
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. Moira O’Bryan, Monash University, Clayton, Victoria, Australia
“Custom cutting – the importance of microtubule severing proteins in male fertility”Host: Anu Sironen
#November
Dentalia, Dent 3, Lemminkäisenkatu 2, Turku
Pieta Mattila, University of Turku
“Exploring B cell activation and the antigen processing route in B cells”Host: Jukka Alinikula
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Prof. Michael McHeyzer-Williams, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, USA
“Deconstructing B cell memory at the single cell level”Host: Liu Chengqian
Dentalia, Dent 3, Lemminkäisenkatu 2, Turku
Linnéa Linko, University of Turku
“Quality requirements in routine laboratory diagnostics and research”Host: Marianne Gunell
Biology seminar room 215, Natura, 2nd floor, Turun yliopisto, natura, Turku, 20500
Adj. prof. Adolfo Rivero-Müller, Turku Centre for Biotechnology
“Gene editing technologies”Host: Päivi Koskinen
Arje Scheinin auditorium, Dentalia, 2nd floor, Lemminkäisenkatu 2, Turku
Prof. Ron van Schaik, Department of Clinical Chemistry, Erasmus Medical Center, Rotterdam, The Netherlands
“Clinical implementation of pharmacogenomics: do you have your DNA passport ready?”Host: Csilla Sipeky
Dentalia, Dent 3, Lemminkäisenkatu 2, Turku
Elina Mäntylä, University of Jyväskylä
“Viral regulation of the cell cycle”Host: Veijo Hukkanen
Auditorium Alpha, ICT-building, Joukahaisenkatu 3-5, Turku
Olga Vitek, College of Science, College of Computer and Information Science, Northeastern University, Boston, USA
“MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments”Host: Laura Elo
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Olga Vitek, College of Science, College of Computer and Information Science, Northeastern University, Boston, USA
“From proteomics to biological insights using statistics”Host: Laura Elo
Dentalia, Dent 3, Lemminkäisenkatu 2, Turku
Pia Rantakari, University of Turku
“Fetal liver endothelium regulates the seeding of tissue-resident macrophages”Host: Eveliina Munukka
Biology seminar room 215, Natura, 2nd floor, Turun yliopisto, natura, Turku, 20500
Dr. Niina Santio, Department of Biology, University of Turku
“Pim kinases in regulation of cell motility”Host: Päivi Koskinen
Dentalia, Dent 3, Lemminkäisenkatu 2, Turku
Teemu Kallonen, Sanger Institute, UK
“Use of whole genome sequencing to analyse Escherichia coli causing bacteremia in England”Host: Erkki Eerola
Dentalia Auditorium (Arje Scheinin), 2nd floor, Lemminkäisenkatu 2, Turku
Anthony Chalmers, Institute of Cancer Sciences, University of Glasgow, Scotland, UK
“Understanding and targeting the abnormal DNA damage response in glioblastoma stem-like cells”Host: Jukka Westermarck
#October
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Prof. Jens Mittag, University of Lübeck, Lübeck, Germany
“Thyroid hormone receptor alpha 1 in the control of cardiovascular function and brown fat thermogenesis”Host: Jukka Kero
Dentalia, Dent 3, Lemminkäisenkatu 2, Turku
Ulvi Gürsoy, University of Turku
“Host bacteria infection”Host: Eija Könönen
Salin Auditorium, Axelia II, Åbo Akademi, Piispankatu 8, Turku
Applications of modern mass spectrometry in life sciences
Programme and registration (by October 24)
Applications of modern mass spectrometry in life sciences
Biology seminar room 215, Natura, 2nd floor, Turun yliopisto, natura, Turku, 20500
Adj. prof. Jussi Jäntti, VTT Synthetic Biology Group, Espoo
“Novel genetic tools for engineering of eukaryotic microbes”Host: Päivi Koskinen
Dentalia, Dent 3, Lemminkäisenkatu 2, Turku
Henna-Maria Uusitupa, University of Turku
“Breastmilk and gut microbiota development”Host: Eveliina Munukka
PharmaCity Auditorium, Itäinen Pitkäkatu 4B, Turku
Professor Anne Ridley, King´s College London, UK
“Rho GTPases: signalling in cell migration”Host: Päivi Koskinen
Turku Centre for Biotechnology, 5th floor seminar room, BioCity B-staircase, Tykistökatu 6, Turku
Speaker: Adam Byron, Edinburgh Cancer Research UK Centre, University of Edinburgh, UK
“Integrative analyses of adhesion signalling networks to identify new cancer targets”
Speaker: Adam Byron, Edinburgh Cancer Research UK Centre, University of Edinburgh, UK
#September
Presidentti auditorium, Mauno Conference Center, BioCity, Tykistökatu 6, Turku
Dr. Sophie Rousseaux, INSERM, Université Grenoble Alpes, Institut Albert Bonniot, Grenoble, France
“Cell identity loss in cancer: a source of new biomarker and therapeutic targets”Host: Noora Kotaja